Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Discovery and Optimization of 4-(8-(3-Fluorophenyl)-1,7-naphthyridin-6-yl)transcyclohexanecarboxylic Acid, an Improved PDE4 Inhibitor for the Treatment of Chronic Obstructive Pulmonary Disease (COPD).

Autor: Press NJ; Novartis Institutes for Biomedical Research , Wimblehurst Road, Horsham, West Sussex RH12 5AB, U.K., Taylor RJ; Novartis Institutes for Biomedical Research , Wimblehurst Road, Horsham, West Sussex RH12 5AB, U.K., Fullerton JD; Novartis Institutes for Biomedical Research , Wimblehurst Road, Horsham, West Sussex RH12 5AB, U.K., Tranter P; Novartis Institutes for Biomedical Research , Wimblehurst Road, Horsham, West Sussex RH12 5AB, U.K., McCarthy C; Novartis Institutes for Biomedical Research , Wimblehurst Road, Horsham, West Sussex RH12 5AB, U.K., Keller TH; Novartis Institutes for Biomedical Research , Wimblehurst Road, Horsham, West Sussex RH12 5AB, U.K., Arnold N; Novartis Institutes for Biomedical Research , Wimblehurst Road, Horsham, West Sussex RH12 5AB, U.K., Beer D; Novartis Institutes for Biomedical Research , Wimblehurst Road, Horsham, West Sussex RH12 5AB, U.K., Brown L; Novartis Institutes for Biomedical Research , Wimblehurst Road, Horsham, West Sussex RH12 5AB, U.K., Cheung R; Novartis Institutes for Biomedical Research , Wimblehurst Road, Horsham, West Sussex RH12 5AB, U.K., Christie J; Novartis Institutes for Biomedical Research , Wimblehurst Road, Horsham, West Sussex RH12 5AB, U.K., Denholm A; Novartis Institutes for Biomedical Research , Wimblehurst Road, Horsham, West Sussex RH12 5AB, U.K., Haberthuer S; Novartis Institutes for Biomedical Research , Wimblehurst Road, Horsham, West Sussex RH12 5AB, U.K., Hatto JD; Novartis Institutes for Biomedical Research , Wimblehurst Road, Horsham, West Sussex RH12 5AB, U.K., Keenan M; Novartis Institutes for Biomedical Research , Wimblehurst Road, Horsham, West Sussex RH12 5AB, U.K., Mercer MK; Novartis Institutes for Biomedical Research , Wimblehurst Road, Horsham, West Sussex RH12 5AB, U.K., Oakman H; Novartis Institutes for Biomedical Research , Wimblehurst Road, Horsham, West Sussex RH12 5AB, U.K., Sahri H; Novartis Institutes for Biomedical Research , Wimblehurst Road, Horsham, West Sussex RH12 5AB, U.K., Tuffnell AR; Novartis Institutes for Biomedical Research , Wimblehurst Road, Horsham, West Sussex RH12 5AB, U.K., Tweed M; Novartis Institutes for Biomedical Research , Wimblehurst Road, Horsham, West Sussex RH12 5AB, U.K., Trifilieff A; Novartis Institutes for Biomedical Research , Wimblehurst Road, Horsham, West Sussex RH12 5AB, U.K.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2015 Sep 10; Vol. 58 (17), pp. 6747-52. Date of Electronic Publication: 2015 Aug 28.

Potent and selective xanthine-based inhibitors of phosphodiesterase 5.

Autor: Arnold NJ; Novartis Institutes of Biomedical Research, Horsham Research Centre, Wimblehurst Road, Horsham, West Sussex RH12 5AB, UK., Arnold R, Beer D, Bhalay G, Collingwood SP, Craig S, Devereux N, Dodds M, Dunstan AR, Fairhurst RA, Farr D, Fullerton JD, Glen A, Gomez S, Haberthuer S, Hatto JD, Howes C, Jones D, Keller TH, Leuenberger B, Moser HE, Muller I, Naef R, Nicklin PA, Sandham DA, Turner KL, Tweed MF, Watson SJ, Zurini M

Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2007 Apr 15; Vol. 17 (8), pp. 2376-9. Date of Electronic Publication: 2006 Nov 10.

The choice of in-hospital or alternative birth environment as related to the concept of control.

Autor: Fullerton JD

Publikováno v: Journal of nurse-midwifery [J Nurse Midwifery] 1982 Mar-Apr; Vol. 27 (2), pp. 17-22.