Optimization of a cardiomyocyte model illuminates role of increased I Na,L in repolarization reserve.

Autor: Fullerton KE; Physiology, Biophysics and Systems Biology Program, Weill Cornell Graduate School of Medical Sciences, New York, New York, United States.; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, New York, United States., Clark AP; Department of Biomedical Engineering, Cornell University, Ithaca, New York, United States., Krogh-Madsen T; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, New York, United States.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, New York, United States., Christini DJ; Department of Physiology and Pharmacology, SUNY Downstate Health Sciences University, Brooklyn, New York, United States.

Publikováno v: American journal of physiology. Heart and circulatory physiology [Am J Physiol Heart Circ Physiol] 2024 Feb 01; Vol. 326 (2), pp. H334-H345. Date of Electronic Publication: 2023 Dec 01.