Pathological response following neoadjuvant immune checkpoint inhibitors in patients with hepatocellular carcinoma: a cross-trial, patient-level analysis.

Autor: D'Alessio A; Division of Cancer, Department of Surgery and Cancer, Imperial College London, London, UK., Stefanini B; Division of Cancer, Department of Surgery and Cancer, Imperial College London, London, UK; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy., Blanter J; Department of Medicine, Division of Hematology-Oncology, Tisch Cancer Institute, Mount Sinai Hospital, New York, NY, USA., Adegbite B; Department of Medicine, Division of Hematology-Oncology, Tisch Cancer Institute, Mount Sinai Hospital, New York, NY, USA., Crowley F; Department of Medicine, Division of Hematology-Oncology, Tisch Cancer Institute, Mount Sinai Hospital, New York, NY, USA., Yip V; Barts and The London HPB Centre, Barts Health NHS Trust, London, UK., Slater S; Department of Medical Oncology, Barts Health NHS Trust, London, UK., Fulgenzi CAM; Division of Cancer, Department of Surgery and Cancer, Imperial College London, London, UK., Celsa C; Division of Cancer, Department of Surgery and Cancer, Imperial College London, London, UK; Gastroenterology and Hepatology Unit, Department of Health Promotion, Mother & Child Care, Internal Medicine & Medical Specialties, University of Palermo, Palermo, Italy., Manfredi GF; Division of Cancer, Department of Surgery and Cancer, Imperial College London, London, UK; Department of Translational Medicine, Università del Piemonte Orientale 'A. Avogadro', Novara, Italy., Pai M; Division of Surgery, Department of Surgery and Cancer, Imperial College London, London, UK., Goldin RD; Department of Digestive Diseases, Imperial College London, St Mary's Hospital, London, UK., Ward SC; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Fiel MI; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Shu DH; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Su YY; National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan; Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Department of Internal Medicine, Kaohsiung Medical University Hospital and Center for Cancer Research, Kaohsiung Medical University, Kaohsiung, Taiwan., Cortellini A; Division of Cancer, Department of Surgery and Cancer, Imperial College London, London, UK; Operative Research Unit of Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, and Department of Medicine and Surgery, Universitá Campus Bio-Medico di Roma, Rome, Italy., Baretti M; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Anders R; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Yarchoan M; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Hsu C; Department of Medical Oncology, National Taiwan University Cancer Center, Taipei, Taiwan; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan., Marron TU; Department of Medicine, Division of Hematology-Oncology, Tisch Cancer Institute, Mount Sinai Hospital, New York, NY, USA., Pinato DJ; Division of Cancer, Department of Surgery and Cancer, Imperial College London, London, UK; Department of Translational Medicine, Università del Piemonte Orientale 'A. Avogadro', Novara, Italy. Electronic address: david.pinato@imperial.ac.uk.

Publikováno v: The Lancet. Oncology [Lancet Oncol] 2024 Nov; Vol. 25 (11), pp. 1465-1475. Date of Electronic Publication: 2024 Oct 19.

Delivering adjuvant and neoadjuvant treatments in the early stages of hepatocellular carcinoma.

Autor: Stefanini B; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, London, UK.; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy., Manfredi GF; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, London, UK.; Division of Internal Medicine, Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy., D'Alessio A; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, London, UK.; Division of Oncology, Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy., Fulgenzi CAM; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, London, UK., Awosika N; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, London, UK., Celsa C; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, London, UK.; Section of Gastroenterology and Hepatology, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, PROMISE, University of Palermo, Palermo, Italy., Pirisi M; Division of Internal Medicine, Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy., Rigamonti C; Division of Internal Medicine, Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy., Burlone M; Division of Internal Medicine, Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy., Vincenzi F; Division of Internal Medicine, Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy., Minisini R; Division of Internal Medicine, Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy., Gennari A; Division of Oncology, Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy., Yip V; Barts and the London HPB Centre, Royal London Hospital, Whitechapel, UK., Slater S; Barts and the London HPB Centre, Royal London Hospital, Whitechapel, UK., El-Shakankery K; Edinburgh Cancer Centre, Western General Hospital, NHS Lothian, Edinburgh, UK., Jain A; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, London, UK., Tovoli F; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.; Division of Internal Medicine, Hepatobiliary and Immunoallergic Diseases, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Piscaglia F; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.; Division of Internal Medicine, Hepatobiliary and Immunoallergic Diseases, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Spalding D; Hepatobiliary Surgery, Imperial College London and Imperial College NHS Trust, Hammersmith Hospital, London, UK., Pai M; Hepatobiliary Surgery, Imperial College London and Imperial College NHS Trust, Hammersmith Hospital, London, UK., Pinato DJ; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, London, UK.; Division of Oncology, Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy.

Publikováno v: Expert review of gastroenterology & hepatology [Expert Rev Gastroenterol Hepatol] 2024 Oct; Vol. 18 (10), pp. 647-660. Date of Electronic Publication: 2024 Oct 22.

Hepatic decompensation is the major driver of mortality in patients with HCC treated with atezolizumab plus bevacizumab: The impact of successful antiviral treatment.

Autor: Celsa C; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, London, UK.; Gastroenterology and Hepatology Unit, Department of Health Promotion, Mother & Child Care, Internal Medicine & Medical Specialties, University of Palermo, Palermo, Italy., Cabibbo G; Gastroenterology and Hepatology Unit, Department of Health Promotion, Mother & Child Care, Internal Medicine & Medical Specialties, University of Palermo, Palermo, Italy., Fulgenzi CAM; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, London, UK., Battaglia S; Department of Economics Business and Statistics, University of Palermo, Palermo, Italy., Enea M; Department of Health Promotion, Mother & Child Care, Internal Medicine & Medical Specialties, University of Palermo, Palermo, Italy., Scheiner B; Department of Internal Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria., D'Alessio A; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, London, UK.; Department of Translational Medicine, Università Del Piemonte Orientale, Novara, Italy., Manfredi GF; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, London, UK.; Department of Translational Medicine, Università Del Piemonte Orientale, Novara, Italy., Stefanini B; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, London, UK.; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy., Nishida N; Department of Gastroenterology and Hepatology, Kindai University, Osaka, Japan., Galle PR; Department of Internal Medicine I, University Medical Center Mainz, Mainz, Germany., Schulze K; Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Wege H; Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Ciccia R; Gastroenterology and Hepatology Unit, Department of Health Promotion, Mother & Child Care, Internal Medicine & Medical Specialties, University of Palermo, Palermo, Italy., Hsu WF; Department of Internal Medicine, Center for Digestive Medicine, China Medical University Hospital, Taichung, Taiwan., Vivaldi C; Translational Research and New Technologies in Medicine and Surgery, Unit of Medical Oncology 2, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy., Wietharn B; Department of Medicine, Division of Medical Oncology, Kansas University Cancer Center, Kansas City, Kansas, USA., Lin RP; Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Taoyuan, Taiwan., Pirozzi A; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.; Medical Oncology and Hematology Unit, Humanitas Cancer Center, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy., Pressiani T; Medical Oncology and Hematology Unit, Humanitas Cancer Center, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy., Dalbeni A; Section of General Medicine C, Medicine Department, University of Verona and University and Hospital Trust (AOUI) of Verona, Verona, Italy.; Liver Unit, Medicine Department, University of Verona and University and Hospital Trust (AOUI) of Verona, Verona, Italy., Natola LA; Liver Unit, Medicine Department, University of Verona and University and Hospital Trust (AOUI) of Verona, Verona, Italy., Auriemma A; Section of Innovation Biomedicine-Oncology Area, Department of Engineering for Innovation Medicine (DIMI), University of Verona and University and Hospital Trust (AOUI) of Verona, Verona, Italy., Rigamonti C; Department of Translational Medicine, Università Del Piemonte Orientale, Novara, Italy., Burlone M; Department of Translational Medicine, Università Del Piemonte Orientale, Novara, Italy., Parisi A; Department of Oncology, Università Politecnica delle Marche, Azienda Ospedaliero-Universitaria delle Marche, Ancona, Italy., Huang YH; Department of Medicine, Healthcare and Services Center, Taipei Veterans General Hospital, Taipei, Taiwan.; Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.; Department of Medicine, Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan., Lee PC; Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.; Department of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan., Ang C; Department of Medicine, Division of Hematology/Oncology, Tisch Cancer Institute, Mount Sinai Hospital, New York, New York, USA., Marron TU; Medical Oncology, Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea., Pinter M; Department of Internal Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria., Cheon J; Medical Oncology, Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea., Phen S; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Singal AG; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Gampa A; Section of Gastroenterology, Hepatology & Nutrition, The University of Chicago Medicine, Chicago, Illinois, USA., Pillai A; Section of Gastroenterology, Hepatology & Nutrition, The University of Chicago Medicine, Chicago, Illinois, USA., Roehlen N; Department of Medicine II (Gastroenterology, Hepatology, Endocrinology and Infectious Diseases), Freiburg University Medical Center, University of Freiburg, Freiburg, Germany., Thimme R; Department of Medicine II (Gastroenterology, Hepatology, Endocrinology and Infectious Diseases), Freiburg University Medical Center, University of Freiburg, Freiburg, Germany., Vogel A; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.; Longo Family Chair in Liver Cancer Research, Division of Gastroenterology and Hepatology, Department of Medicine, Toronto General Hospital, Medical Oncology, Princess Margaret Cancer Centre, Schwartz Reisman Liver Research Centre, Toronto, Canada., Soror N; Department of Internal Medicine, Medical Oncology/TSET Phase 1 Program, Stephenson Cancer Center, University of Oklahoma, Oklahoma City, Oklahoma, USA., Ulahannan S; Department of Internal Medicine, Medical Oncology/TSET Phase 1 Program, Stephenson Cancer Center, University of Oklahoma, Oklahoma City, Oklahoma, USA., Sharma R; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, London, UK., Sacerdoti D; Liver Unit, Medicine Department, University of Verona and University and Hospital Trust (AOUI) of Verona, Verona, Italy., Pirisi M; Department of Translational Medicine, Università Del Piemonte Orientale, Novara, Italy., Rimassa L; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.; Medical Oncology and Hematology Unit, Humanitas Cancer Center, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy., Lin CY; Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Taoyuan, Taiwan., Saeed A; Department of Medicine, Division of Hematology & Oncology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Masi G; Translational Research and New Technologies in Medicine and Surgery, Unit of Medical Oncology 2, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy., Schönlein M; Department of Oncology, Hematology and Bone Marrow Transplantation with Section of Pneumology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., von Felden J; Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Kudo M; Department of Gastroenterology and Hepatology, Kindai University, Osaka, Japan., Cortellini A; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, London, UK.; Operative Research Unit of Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, Roma, Italy., Chon HJ; Medical Oncology, Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea., Cammà C; Gastroenterology and Hepatology Unit, Department of Health Promotion, Mother & Child Care, Internal Medicine & Medical Specialties, University of Palermo, Palermo, Italy., Pinato DJ; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, London, UK.; Department of Translational Medicine, Università Del Piemonte Orientale, Novara, Italy.

Publikováno v: Hepatology (Baltimore, Md.) [Hepatology] 2024 Jul 19. Date of Electronic Publication: 2024 Jul 19.

The Hammersmith Score Optimises Patient Selection and Predicts for Overall Survival in Early-Phase Cancer Trial Participants Independent of Tumour Burden.

Autor: Korolewicz JA; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, UK., Scheiner B; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, UK.; Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria., Fulgenzi CAM; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, UK.; Department of Medical Oncology, University Campus Bio-Medico of Rome, Roma, Italy., D'Alessio A; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, UK.; Department of Translational Medicine, Università del Piemonte Orientale (UPO), Novara, Italy., Cortellini A; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, UK.; Operative Research Unit of Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, Roma, Italy., Pascual C; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, UK., Mehan A; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, UK., Partridge S; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, UK., Gujral DM; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, UK., Mohammed W; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, UK., Mohammed O; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, UK., Grzesiak A; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, UK., Booker L; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, UK., Cleator S; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, UK., Pokrovska T; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, UK., Saleem W; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, UK., Rackie J; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, UK., Needham Y; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, UK., Krell J; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, UK., McNeish I; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, UK., Tookman L; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, UK., Park WE; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, UK., Asif M; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, UK., Evans JS; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, UK., Pinato DJ; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, UK.; Department of Translational Medicine, Università del Piemonte Orientale (UPO), Novara, Italy.

Publikováno v: Chemotherapy [Chemotherapy] 2024 Apr 27, pp. 1-7. Date of Electronic Publication: 2024 Apr 27.

Characteristics and outcomes of immunotherapy-related liver injury in patients with hepatocellular carcinoma versus other advanced solid tumours.

Autor: Celsa C; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, W120HS London, UK; Gastroenterology and Hepatology Unit, Department of Health Promotion, Mother & Child Care, Internal Medicine & Medical Specialties, University of Palermo, Italy., Cabibbo G; Gastroenterology and Hepatology Unit, Department of Health Promotion, Mother & Child Care, Internal Medicine & Medical Specialties, University of Palermo, Italy., Fulgenzi CAM; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, W120HS London, UK; Operative Research Unit of Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, 200 - 00128 Roma, Italy., Scheiner B; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, W120HS London, UK; Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria., D'Alessio A; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, W120HS London, UK; Division of Oncology, Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy., Manfredi GF; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, W120HS London, UK; Division of Oncology, Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy., Nishida N; Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka, Japan., Ang C; Department of Medicine, Division of Hematology/Oncology, Tisch Cancer Institute, Mount Sinai Hospital, New York, NY, USA., Marron TU; Department of Medicine, Division of Hematology/Oncology, Tisch Cancer Institute, Mount Sinai Hospital, New York, NY, USA., Saeed A; Department of Medicine, Division of Hematology & Oncology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Wietharn B; Department of Medicine, Division of Medical Oncology, Kansas University Cancer Center, Kansas City, Kansas, USA., Pinter M; Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria., Cheon J; Medical Oncology, Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, South Korea., Huang YH; Healthcare and Services Center, Taipei Veterans General Hospital, Taipei, Taiwan; Division of Gastroenterology and Hepatology, Taipei Veterans General Hospital, Taipei, Taiwan; Institute of Clinical Medicine, Faculty of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan., Lee PC; Division of Gastroenterology and Hepatology, Taipei Veterans General Hospital, Taipei, Taiwan; Faculty of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan., Phen S; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Gampa A; Section of Gastroenterology, Hepatology & Nutrition, the University of Chicago Medicine 5841 S. Maryland Ave, 60637 Chicago, IL, USA., Pillai A; Unit of Medical Oncology 2, Azienda Ospedaliero- Universitaria Pisana, Pisa, Italy., Vivaldi C; Scuola Superiore Sant'Anna Pisa, interdisciplinary research center 'Health Science', Pisa, Italy., Salani F; Unit of Medical Oncology 2, Azienda Ospedaliero- Universitaria Pisana, Pisa, Italy; Scuola Superiore Sant'Anna Pisa, interdisciplinary research center 'Health Science', Pisa, Italy., Masi G; Unit of Medical Oncology 2, Azienda Ospedaliero- Universitaria Pisana, Pisa, Italy., Roehlen N; Department of Medicine II (Gastroenterology, Hepatology, Endocrinology and Infectious Diseases), Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Thimme R; Department of Medicine II (Gastroenterology, Hepatology, Endocrinology and Infectious Diseases), Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Vogel A; Hannover Medical School, Hannover, Germany; Longo Family Chair in Liver Cancer Research, Division of Gastroenterology and Hepatology, Toronto General Hospital, Medical Oncology, Princess Margaret Cancer Centre, Schwartz Reisman Liver Research Centre, Toronto, Canada., Schönlein M; Department of Oncology, Hematology and Bone Marrow Transplantation with Section of Pneumology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., von Felden J; Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Schulze K; Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Wege H; Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Galle PR; University Medical Center Mainz, Department of Internal Medicine I, Mainz, Germany., Kudo M; Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka, Japan., Rimassa L; Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20072 Pieve Emanuele, Milan, Italy; Medical Oncology and Hematology Unit, Humanitas Cancer Center, IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, Milan, Italy., Singal AG; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA., El Tomb P; Medical Oncology/TSET Phase 1 Program, Stephenson Cancer Center, University of Oklahoma, Oklahoma City., Ulahannan S; Medical Oncology/TSET Phase 1 Program, Stephenson Cancer Center, University of Oklahoma, Oklahoma City., Parisi A; Department of Oncology, Università Politecnica delle Marche, Azienda Ospedaliero-Universitaria delle Marche, 60126 Ancona, Italy., Chon HJ; Medical Oncology, Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, South Korea., Hsu WF; Center for Digestive Medicine, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan., Stefanini B; Department of Medical and Surgical Sciences, University of Bologna, Italy., Verzoni E; SS. Oncologia Genitourinaria, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy., Giusti R; Medical Oncology Unit, Sant'Andrea Hospital, Roma, Italy., Veccia A; Medical Oncology, Santa Chiara Hospital, Trento, Italy., Catino A; Medical Thoracic Oncology Unit, IRCCS Istituto Tumori 'Giovanni Paolo II', Bari, Italy., Aprile G; Department of Oncology, San Bortolo General Hospital, Vicenza, Italy., Guglielmini PF; SC Oncologia, AO SS Antonio e Biagio e C. Arrigo, Alessandria, Italy., Di Napoli M; UC Oncologia Medica Uro-Ginecologica, Istituto Nazionale Tumori 'Fondazione G. Pascale', IRCCS, Napoli, Italy., Ermacora P; Dipartimento di Oncologia, Presidio Ospedaliero Universitario Santa Maria della Misericordia, Azienda sanitaria universitaria Integrata Friuli Centrale, Udine, Italy., Antonuzzo L; Medical Oncology Unit, University Hospital Careggi, Firenze, Italy., Rossi E; Medical Oncology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy., Verderame F; Oncology Department, Ospedali Riuniti Villa Sofia Cervello, Palermo, Italy., Zustovich F; UOC Oncologia di Belluno, Dipartimento di Oncologia Clinica, AULSS 1 Dolomiti, Ospedale S.Martino, Belluno, Italy., Ficorella C; Department of Biotechnological and Applied Clinical Sciences, St Salvatore Hospital, University of L'Aquila, L'Aquila, Italy., Di Pietro FR; U.O.C. Oncologia, Istituto Dermopatico dell'Immacolata IDI-IRCCS, Roma, Italy., Battelli N; UOC Oncologia, Ospedale Generale Provinciale di Macerata, ASUR Marche Area Vasta 3, Macerata, Italy., Negrini G; Medical Oncology Unit, Papa Giovanni XXIII Hospital, Bergamo, Italy., Grossi F; Medical Oncology Department, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Bordonaro R; Medical Oncology Unit, ARNAS Garibaldi, Catania, Italy., Pipitone S; Medical Oncology Unit, University Hospital of Modena e Reggio Emilia, Italy., Banzi M; Medical Oncology Unit, AUSL-IRCCS of Reggio Emilia, Reggio Emilia, Italy., Ricciardi S; Medical Oncology, San Camillo Forlanini Hospital, Roma, Italy., Laera L; Medical Oncology, Ospedale Generale Regionale F Miulli, Acquaviva delle Fonti, Puglia, Italy., Russo A; Dipartimento di Discipline Chirurgiche, Oncologiche e Stomatologiche, Università degli Studi di Palermo, Palermo, Italy., De Giorgi U; Department of Medical Oncology, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy., Cavanna L; Oncologia Medica, ASL di Piacenza, Piacenza, Italy., Sorarù M; Medical Oncology, Camposampiero Hospital, AULSS 6 Euganea, Padova, Italy., Montesarchio V; UOC Oncologia, Ospedale Monaldi, Azienda Ospedaliera Specialistica dei Colli, Napoli, Italy., Bordi P; Medical Oncology Unit, Medicine and Surgery Department, University of Parma, Parma, Italy., Brunetti L; Operative Research Unit of Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, 200 - 00128 Roma, Italy., Pinto C; Medical Oncology Unit, AUSL-IRCCS of Reggio Emilia, Reggio Emilia, Italy., Bersanelli M; Medical Oncology Unit, Medicine and Surgery Department, University of Parma, Parma, Italy., Cammà C; Gastroenterology and Hepatology Unit, Department of Health Promotion, Mother & Child Care, Internal Medicine & Medical Specialties, University of Palermo, Italy., Cortellini A; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, W120HS London, UK; Operative Research Unit of Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, 200 - 00128 Roma, Italy., Pinato DJ; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, W120HS London, UK; Division of Oncology, Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy. Electronic address: david.pinato@imperial.ac.uk.

Publikováno v: Journal of hepatology [J Hepatol] 2024 Mar; Vol. 80 (3), pp. 431-442. Date of Electronic Publication: 2023 Nov 15.