Unsynchronized butyrophilin molecules dictate cancer cell evasion of Vγ9Vδ2 T-cell killing.

Autor: Wu Z; Biomedical Pioneering Innovation Center, Peking-Tsinghua Center for Life Sciences, Peking University Genome Editing Research Center, State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, 100871, Beijing, China., Lamao Q; Biomedical Pioneering Innovation Center, Peking-Tsinghua Center for Life Sciences, Peking University Genome Editing Research Center, State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, 100871, Beijing, China., Gu M; Biomedical Pioneering Innovation Center, Peking-Tsinghua Center for Life Sciences, Peking University Genome Editing Research Center, State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, 100871, Beijing, China., Jin X; Biomedical Pioneering Innovation Center, Peking-Tsinghua Center for Life Sciences, Peking University Genome Editing Research Center, State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, 100871, Beijing, China., Liu Y; Biomedical Pioneering Innovation Center, Peking-Tsinghua Center for Life Sciences, Peking University Genome Editing Research Center, State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, 100871, Beijing, China., Tian F; Biomedical Pioneering Innovation Center, Peking-Tsinghua Center for Life Sciences, Peking University Genome Editing Research Center, State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, 100871, Beijing, China., Yu Y; Biomedical Pioneering Innovation Center, Peking-Tsinghua Center for Life Sciences, Peking University Genome Editing Research Center, State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, 100871, Beijing, China., Yuan P; EdiGene Inc., Life Science Park, Changping District, 102206, Beijing, China., Gao S; Center for Precision Medicine Multi-Omics Research, Peking University Health Science Center, Peking University, 100191, Beijing, China., Fulford TS; Department of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, VIC, 3010, Australia., Uldrich AP; Department of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, VIC, 3010, Australia.; Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., Wong CC; State Key Laboratory for Complex, Severe and Rare Diseases, Clinical Research Institute, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Peking-Tsinghua Center for Life Sciences, 100871, Beijing, China. catclw321@126.com., Wei W; Biomedical Pioneering Innovation Center, Peking-Tsinghua Center for Life Sciences, Peking University Genome Editing Research Center, State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, 100871, Beijing, China. wswei@pku.edu.cn.

Publikováno v: Cellular & molecular immunology [Cell Mol Immunol] 2024 Apr; Vol. 21 (4), pp. 362-373. Date of Electronic Publication: 2024 Feb 20.

Expansion of MAIT cells in the combined absence of NKT and γδ-T cells.

Autor: Xu C; Department of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, Australia., Li S; Department of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, Australia., Fulford TS; Department of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, Australia., Christo SN; Department of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, Australia., Mackay LK; Department of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, Australia., Gray DH; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia; Department of Medical Biology, University of Melbourne, Parkville, Australia., Uldrich AP; Department of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, Australia., Pellicci DG; Department of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, Australia; Murdoch Children's Research Institute, Melbourne, Australia; Department of Paediatrics, University of Melbourne, Parkville, Australia. Electronic address: dan.pellicci@mcri.edu.au., I Godfrey D; Department of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, Australia. Electronic address: godfrey@unimelb.edu.au., Koay HF; Department of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, Australia. Electronic address: hf.koay@unimelb.edu.au.

Publikováno v: Mucosal immunology [Mucosal Immunol] 2023 Aug; Vol. 16 (4), pp. 446-461. Date of Electronic Publication: 2023 May 13.

A point-of-care lateral flow assay for neutralising antibodies against SARS-CoV-2.

Autor: Fulford TS; Department of Microbiology and Immunology, University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia., Van H; Burnet Institute, Melbourne, Victoria, Australia., Gherardin NA; Department of Microbiology and Immunology, University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, University of Melbourne, Melbourne, Victoria, Australia., Zheng S; Burnet Institute, Melbourne, Victoria, Australia., Ciula M; Department of Microbiology and Immunology, University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia., Drummer HE; Department of Microbiology and Immunology, University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia; Burnet Institute, Melbourne, Victoria, Australia; Department of Microbiology, Monash University, Australia., Redmond S; Department of Microbiology and Immunology, University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia., Tan HX; Department of Microbiology and Immunology, University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia., Boo I; Burnet Institute, Melbourne, Victoria, Australia., Center RJ; Department of Microbiology and Immunology, University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia; Burnet Institute, Melbourne, Victoria, Australia., Li F; Burnet Institute, Melbourne, Victoria, Australia., Grimley SL; Department of Microbiology and Immunology, University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia., Wines BD; Immune therapies Laboratory, Burnet Institute, Melbourne, VIC, Australia,; Department of Immunology and Pathology, Central Clinical School, Monash University, Melbourne, VIC, Australia; Department of Clinical Pathology, The University of Melbourne, Parkville, VIC, Australia., Nguyen THO; Department of Microbiology and Immunology, University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia., Mordant FL; Department of Microbiology and Immunology, University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia., Ellenberg P; Department of Microbiology and Immunology, University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia., Rowntree LC; Department of Microbiology and Immunology, University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia., Kedzierski L; Department of Microbiology and Immunology, University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia., Cheng AC; Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia., Doolan DL; Australian Institute of Tropical Health & Medicine, James Cook University, Cairns, Queensland, Australia., Matthews G; Kirby Institute, University of NSW, Sydney, NSW, Australia., Bond K; Department of Microbiology and Immunology, University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia; Department of Microbiology, Royal Melbourne Hospital, Melbourne, Australia., Hogarth PM; Immune therapies Laboratory, Burnet Institute, Melbourne, VIC, Australia,; Department of Immunology and Pathology, Central Clinical School, Monash University, Melbourne, VIC, Australia; Department of Clinical Pathology, The University of Melbourne, Parkville, VIC, Australia., McQuilten Z; Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia., Subbarao K; Department of Microbiology and Immunology, University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia; WHO Collaborating Centre for Reference and Research on Influenza at the Peter Doherty Institute for Infection and Immunity., Kedzierska K; Department of Microbiology and Immunology, University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia., Juno JA; Department of Microbiology and Immunology, University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia., Wheatley AK; Department of Microbiology and Immunology, University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia; Melbourne Sexual Health Centre and Department of Infectious Diseases, Alfred Hospital and Central Clinical School, Monash University, Melbourne, Victoria, Australia., Kent SJ; Department of Microbiology and Immunology, University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia; Melbourne Sexual Health Centre and Department of Infectious Diseases, Alfred Hospital and Central Clinical School, Monash University, Melbourne, Victoria, Australia; Australian Research Council Centre for Excellence in Convergent Bio-Nano Science and Technology, University of Melbourne, Melbourne, Victoria, Australia., Williamson DA; Department of Microbiology and Immunology, University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia; Department of Microbiology, Royal Melbourne Hospital, Melbourne, Australia., Purcell DFJ; Department of Microbiology and Immunology, University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia., Anderson DA; Burnet Institute, Melbourne, Victoria, Australia. Electronic address: david.anderson@burnet.edu.au., Godfrey DI; Department of Microbiology and Immunology, University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, University of Melbourne, Melbourne, Victoria, Australia. Electronic address: godfrey@unimelb.edu.au.

Publikováno v: EBioMedicine [EBioMedicine] 2021 Dec; Vol. 74, pp. 103729. Date of Electronic Publication: 2021 Dec 03.

c-Rel Is Required for IL-33-Dependent Activation of ILC2s.

Autor: Zaini A; Infection and Immunity Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, Australia., Fulford TS; Department of Microbiology and Immunology, University of Melbourne, The Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia., Grumont RJ; Infection and Immunity Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, Australia., Runting J; Infection and Immunity Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, Australia., Rodrigues G; Infection and Immunity Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, Australia., Ng J; Infection and Immunity Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, Australia., Gerondakis S; Infection and Immunity Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, Australia., Zaph C; Infection and Immunity Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, Australia., Scheer S; Infection and Immunity Program, Monash Biomedicine Discovery Institute, Clayton, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, Australia.

Publikováno v: Frontiers in immunology [Front Immunol] 2021 Jun 14; Vol. 12, pp. 667922. Date of Electronic Publication: 2021 Jun 14 (Print Publication: 2021).

Butyrophilin 2A1 is essential for phosphoantigen reactivity by γδ T cells.

Autor: Rigau M; Department of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, Victoria 3010, Australia.; University of Bonn, Bonn, Germany.; Australian Research Council Centre of Excellence for Advanced Molecular Imaging at the University of Melbourne, Victoria 3010, Australia., Ostrouska S; Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria 3084, Australia.; School of Cancer Medicine, La Trobe University, Heidelberg, Victoria 3084, Australia., Fulford TS; Department of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, Victoria 3010, Australia., Johnson DN; Department of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, Victoria 3010, Australia.; Australian Research Council Centre of Excellence for Advanced Molecular Imaging at the University of Melbourne, Victoria 3010, Australia., Woods K; Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria 3084, Australia.; School of Cancer Medicine, La Trobe University, Heidelberg, Victoria 3084, Australia.; Ludwig Institute for Cancer Research, Melbourne -Austin Branch, Victoria 3084, Australia., Ruan Z; Department of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, Victoria 3010, Australia.; Australian Research Council Centre of Excellence for Advanced Molecular Imaging at the University of Melbourne, Victoria 3010, Australia., McWilliam HEG; Department of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, Victoria 3010, Australia.; Department of Biochemistry and Molecular Biology at the Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria 3010, Australia., Hudson C; Ludwig Institute for Cancer Research, Melbourne -Austin Branch, Victoria 3084, Australia., Tutuka C; Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria 3084, Australia.; School of Cancer Medicine, La Trobe University, Heidelberg, Victoria 3084, Australia., Wheatley AK; Department of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, Victoria 3010, Australia.; Australian Research Council Centre of Excellence for Convergent Bio-Nano Science and Technology at the University of Melbourne, Victoria 3010, Australia., Kent SJ; Department of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, Victoria 3010, Australia.; Australian Research Council Centre of Excellence for Convergent Bio-Nano Science and Technology at the University of Melbourne, Victoria 3010, Australia., Villadangos JA; Department of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, Victoria 3010, Australia.; Department of Biochemistry and Molecular Biology at the Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria 3010, Australia., Pal B; Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria 3084, Australia.; School of Cancer Medicine, La Trobe University, Heidelberg, Victoria 3084, Australia., Kurts C; University of Bonn, Bonn, Germany., Simmonds J; CSL Limited at the Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria 3010, Australia., Pelzing M; CSL Limited at the Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria 3010, Australia., Nash AD; CSL Limited at the Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria 3010, Australia., Hammet A; CSL Limited at the Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria 3010, Australia., Verhagen AM; CSL Limited at the Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria 3010, Australia., Vairo G; CSL Limited at the Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria 3010, Australia., Maraskovsky E; CSL Limited at the Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria 3010, Australia., Panousis C; CSL Limited at the Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria 3010, Australia., Gherardin NA; Department of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, Victoria 3010, Australia., Cebon J; Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria 3084, Australia.; School of Cancer Medicine, La Trobe University, Heidelberg, Victoria 3084, Australia.; Ludwig Institute for Cancer Research, Melbourne -Austin Branch, Victoria 3084, Australia.; Department of Medicine, The University of Melbourne, Melbourne, Victoria 3010, Australia.; Austin Health, Heidelberg, Victoria 3084, Australia., Godfrey DI; Department of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, Victoria 3010, Australia. auldrich@unimelb.edu.au andreas.behren@onjcri.org.au godfrey@unimelb.edu.au.; Australian Research Council Centre of Excellence for Advanced Molecular Imaging at the University of Melbourne, Victoria 3010, Australia., Behren A; Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria 3084, Australia. auldrich@unimelb.edu.au andreas.behren@onjcri.org.au godfrey@unimelb.edu.au.; School of Cancer Medicine, La Trobe University, Heidelberg, Victoria 3084, Australia.; Ludwig Institute for Cancer Research, Melbourne -Austin Branch, Victoria 3084, Australia.; Department of Medicine, The University of Melbourne, Melbourne, Victoria 3010, Australia., Uldrich AP; Department of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, Victoria 3010, Australia. auldrich@unimelb.edu.au andreas.behren@onjcri.org.au godfrey@unimelb.edu.au.; Australian Research Council Centre of Excellence for Advanced Molecular Imaging at the University of Melbourne, Victoria 3010, Australia.

Publikováno v: Science (New York, N.Y.) [Science] 2020 Feb 07; Vol. 367 (6478). Date of Electronic Publication: 2020 Jan 09.