Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Fukiko Kojima"'
Autor:
Ryuichi Sawa, Naoko Kinoshita, Yoshio Nishimura, Fukiko Kojima, Koichi Nakae, Yuzuru Akamatsu, Masayuki Igarashi, Hayamitu Adachi, Yumiko Kubota
Publikováno v:
The Journal of Antibiotics. 63:41-44
Antipain Y, a new antipain analog that inhibits neurotransmitter release from rat dorsal root ganglion neurons
Autor:
Hotta Kunimoto, Yuzuru Akamatsu, Ken-ichiro Kondo, Yoshio Nishimura, Fukiko Kojima, Hayamitsu Adachi, Yoji Umezawa, Keiko Ishino
Publikováno v:
Letters in Drug Design & Discovery. 5:336-339
Autor:
Ken-ichiro Kondo, Hayamitsu Adachi, Fukiko Kojima, Kunimoto Hotta, Keiko Ishino, Yoshio Nishimura, Yoji Umezawa
Publikováno v:
Natural Product Research. 20:361-370
3-Deoxy-D-manno-octulosonate cytidyltransferase (CMP-KDO synthetase) is involved in the biosynthesis of lipopolysaccharide (LPS) which is an essential component of the outer membrane of gram-negative bacteria. New CMP-KDO synthetase inhibitors, 8-sub
Autor:
Akio Nomoto, Fukiko Kojima, Yumiko Kubota, Masayuki Igarashi, Koichi Nakae, Masaki Hatano, Ryuichi Sawa, Ikuko Kurata, Hayamitsu Adachi
Publikováno v:
Journal of Natural Products. 76:720-722
Sacchathridine A (1) was isolated from the fermentation broth of strain Saccharothrix sp. MI559-46F5. The structure was determined as a new naphthoquinone derivative with an acetylhydrazino moiety by a combination of NMR, MS spectral analyses, and ch
Publikováno v:
Bioorganic & Medicinal Chemistry. 8:343-352
An efficient route from D-ribono-gamma-lactone to gem-diamine 1-N-iminosugars of L-fucose-type, a new family of glycosidase inhibitor, has been developed in a formation of a gem-diamine 1-N-iminopyranose ring by the Mitsunobu reaction of an aminal as
Publikováno v:
Bioorganic & Medicinal Chemistry. 7:1241-1246
gem-Diamine 1-N iminosugars of d -glucose-type, a new type of glycosidase inhibitors, have been synthesized from siastatin B, isolated from Streptomyces culture. 2-Trifluoroacetamido-1-N-iminosugar, (2S,3R,4R,5R)-2-trifluoroacetamido-5-hydroxymethylp
Autor:
Manabu Kawada, Yoshio Nishimura, Shuichi Sakamoto, Fukiko Kojima, Hayamitsu Adachi, Isao Momose
Publikováno v:
Biochemical and biophysical research communications. 422(4)
Decalpenic acid is a natural small molecule previously isolated from the fermentation broth of fungi that induces early osteoblastic markers in pluripotent mesenchymal cells. Treatment of mouse pluripotent mesenchymal C3H10T1/2 cells with decalpenic
Publikováno v:
Biological and Pharmaceutical Bulletin. 17:348-351
We investigated the age-dependency of serum levels of 9 kinds of proteases. The results showed that the enzymatic activities corresponding to urokinase, plasmin, and thrombin, all involved in blood clotting and fibrinolysis, were inversely correlated
Autor:
Kunihiro Isse, Takao Wada, Takaaki Aoyagi, Makoto Hamamoto, Mitsuo Ogura, Fukiko Kojima, Takehiko Nagao, Shigeko Harada, Machiko Nagai, Tomio Takeuchi, Kuniaki Tanaka
Publikováno v:
Journal of Clinical Biochemistry and Nutrition. 14:133-139
Previously, we reported protease changes in cerebral tissues, as well as in serum, of patients with Alzheimer-type dementia. In the present study, we investigated enzymatic activities in their cerebrospinal fluid. In the Alzheimer patients the activi
Autor:
Masatoshi Abe, Yoshikazu Takahashi, Yasuhiko Muraoka, Masa Hamada, Akihito Yamaguchi, Shigeko Harada, Tetsuo Akiyama, Tomio Takeuchi, Yoshiko Homma, Hiroshi Naganawa, Takaaki Aoyagi, Ryuichi Sawa, Fukiko Kojima
Publikováno v:
The Journal of Antibiotics. 54:744-746