Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Fukang Yang"'
Publikováno v:
ACS Omega, Vol 6, Iss 3, Pp 2276-2283 (2021)
Externí odkaz:
https://doaj.org/article/88fd5dcbbe5d472487114e71a058765a
Publikováno v:
IEEE Transactions on Knowledge and Data Engineering. :1-14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8cf19eb02cb713d5686d09be7a831f2
https://doi.org/10.1109/tkde.2023.3243239
https://doi.org/10.1109/tkde.2023.3243239
Publikováno v:
Nucleic Acids in Medicinal Chemistry and Chemical Biology. :113-131
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd767740270378fae577bfd2268ee883
https://doi.org/10.1002/9781119692799.ch4
https://doi.org/10.1002/9781119692799.ch4
Publikováno v:
Polymer Composites. 43:9054-9066
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac92c96fdb1a048373390bd9749ec543
https://doi.org/10.1002/pc.27083
https://doi.org/10.1002/pc.27083
Autor:
Cullen L. Cavallaro, Merrill L. Davies, E. Scott Priestley, Fukang Yang, Chandan L. Barhate, Yong Zhang, Harold N. Weller, G. Greg Zipp, Andrew F. Donnell, Regina Black, Yingru Zhang, Ling Li
Publikováno v:
Chemical communications (Cambridge, England). 57(84)
In recent years, successful assay miniaturization has enabled the exploration of synthesis scale reduction in pharmaceutical discovery. Miniaturization of pharmaceutical synthesis and purification allows a reduction in material consumption and shorte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee291c401f71b21201f45f5a630f5e1a
https://pubmed.ncbi.nlm.nih.gov/34608906
https://pubmed.ncbi.nlm.nih.gov/34608906
Publikováno v:
INFOCOM
Points-of-interest (POIs) recommendation plays a vital role by introducing unexplored POIs to consumers and has drawn extensive attention from both academia and industry. Existing POI recommender systems usually learn latent vectors to represent both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::117e2e81ff83a0b812f1b64786d44439
https://doi.org/10.1109/infocom42981.2021.9488726
https://doi.org/10.1109/infocom42981.2021.9488726
Autor:
Alicia Ng, Andrea McClure, Chiehying Chang, Fukang Yang, Hyunsoo Park, Yong-Jin Wu, Jason M. Guernon, Jianliang Shi, John E. Macor, Charles F. Albright, Ramkumar Rajamani, Michael K. Ahlijanian, Lorin A. Thompson, Jeremy H. Toyn, Lawrence B. Snyder, Hal A. Lewis, Dan Camac
Publikováno v:
ACS Medicinal Chemistry Letters. 7:271-276
By targeting the flap backbone of the BACE1 active site, we discovered 6-dimethylisoxazole-substituted biaryl aminothiazine 18 with 34-fold improved BACE1 inhibitory activity over the lead compound 1. The cocrystal structure of 18 bound to the active
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b111313cde46f71e7929dfe2b01832d
https://doi.org/10.1021/acsmedchemlett.5b00432
https://doi.org/10.1021/acsmedchemlett.5b00432
Autor:
Xiaoliang Zhuo, Xiaohua Stella Huang, Benjamin M. Johnson, Andrew P. Degnan, Yue-Zhong Shu, Fukang Yang, Hong Huang, Lawrence B. Snyder
Publikováno v:
Drug Metabolism and Disposition. 43:578-589
A recent medicinal chemistry campaign to identify positive allosteric modulators (PAMs) of metabotropic glutamate receptor subtype 5 (mGluR5) led to the discovery of potent compounds featuring an oxazolidinone structural core flanked by biaryl acetyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc6a35aa479c877911ebe060df6e3085
https://doi.org/10.1124/dmd.114.061879
https://doi.org/10.1124/dmd.114.061879
Autor:
Mendi A. Higgins, Jianliang Shi, Lawrence R. Marcin, Yong-Jin Wu, Jason M. Guernon, Fukang Yang, Lorin A. Thompson, Lawrence B. Snyder
Publikováno v:
Tetrahedron Letters. 55:2134-2137
A series of β-disubstituted N-sulfinyl β-amino isoxazolyl ketones has been prepared by addition of tert-butanesulfinyl ketimines with the n-BuLi-generated enolates of isoxazolyl methyl ketones.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::293c93c3d5dffa2f2afa9596a1316b52
https://doi.org/10.1016/j.tetlet.2014.02.053
https://doi.org/10.1016/j.tetlet.2014.02.053
Autor:
Donald R. O'Boyle, Anjaneya Chimalakonda, Benjamin M. Johnson, Lavoie Rico, Alain Martel, James Clint A, Denis R. St. Laurent, Julie A. Lemm, Van N. Nguyen, David R. Langley, Henry S. Wong, Fukang Yang, Robert A. Fridell, Deon Daniel H, Juliang Zhu, Glenn H. Cantor, Lawrence B. Snyder, Jeffrey L. Romine, Makonen Belema, Lopez Omar D, Kenneth S. Santone, Carol Bachand, Goodrich Jason, Ruediger Edward H, Richard J. Colonno, Stephen P. Adams, Nicholas A. Meanwell, Min Gao, Aberra Fura, Lawrence G. Hamann, Dawn D. Parker, Jay O. Knipe
Publikováno v:
Journal of Medicinal Chemistry. 57:2013-2032
The biphenyl derivatives 2 and 3 are prototypes of a novel class of NS5A replication complex inhibitors that demonstrate high inhibitory potency toward a panel of clinically relevant HCV strains encompassing genotypes 1-6. However, these compounds ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccb09c433565e97a1989a67acd31dde3
https://doi.org/10.1021/jm401836p
https://doi.org/10.1021/jm401836p