Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Fujun Yu"'
Autor:
Zhoufeng Chen, Liuwei Zeng, Zhuoyan Chen, Jun Xu, Xiangting Zhang, Huiya Ying, Yuan Zeng, Fujun Yu MD
Publikováno v:
Technology in Cancer Research & Treatment, Vol 23 (2024)
Hepatocellular carcinoma (HCC), partly because of its complexity and high heterogeneity, has a poor prognosis and an extremely high mortality rate. In this study, mRNA sequencing expression profiles and relevant clinical data of HCC patients were gat
Externí odkaz:
https://doaj.org/article/14c8d4452dbd444e85a80814058ecba6
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-12 (2023)
Abstract Background The triglyceride-glucose (TyG) index was significantly associated with insulin resistance (IR). Several studies have validated the effect of TyG index on cerebrovascular disease. However, the value of TyG index in patients with se
Externí odkaz:
https://doaj.org/article/e8eee28c6a6f4a8d9506c60198e2c0ef
Autor:
Luying Zhao, Jun Xu, Xiangting Zhang, Qian Xu, Kanglei Ying, Weimin Cai, Yinrong Ding, Huiya Ying, Xian Song, Zhuoyan Chen, Liuwei Zeng, Xiao Wu, Ruoru Zhou, Yuan Zeng, Fujun Yu
Publikováno v:
Journal of Functional Foods, Vol 110, Iss , Pp 105872- (2023)
Acetaminophen (APAP) overdose is the leading cause of drug-induced acute liver injury. However, the underlying mechanisms appear to be multifaceted and there are few effective treatments. In this study, we used the 2′-Hydroxycinnamaldehyde (HCA), a
Externí odkaz:
https://doaj.org/article/ea69a974e1564d5e83a1c2d00d3b8e9c
Autor:
Jun Xu, Luying Zhao, Xiangting Zhang, Kanglei Ying, Ruoru Zhou, Weimin Cai, Xiao Wu, Haoran Jiang, Qian Xu, Dan Miao, Yuan Zeng, Fujun Yu
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 262, Iss , Pp 115331- (2023)
Acetaminophen (APAP) overdose has long been considered a major cause of drug-induced liver injury. Ferroptosis is a type of programmed cell death mediated by iron-dependent lipid peroxidation. Endoplasmic reticulum (ER) stress is a systemic response
Externí odkaz:
https://doaj.org/article/fde23ed892c145e792a0cf8600c607f7
Autor:
Dezhao Lin, Zhuoyan Chen, Yuan Zeng, Yinrong Ding, Luying Zhao, Qian Xu, Fujun Yu, Xian Song, Xiaohong Zhu
Publikováno v:
BMC Medical Genomics, Vol 16, Iss 1, Pp 1-12 (2023)
Abstract Background Hepatocellular Carcinoma (HCC) is a common malignant neoplasm with limited treatment options and poor outcomes. Thus, there is an urgent need to find sensitive biomarkers for HCC. Methods Gene expression and clinicopathological in
Externí odkaz:
https://doaj.org/article/0490f793a55f471b8df70fe51edcacc2
Publikováno v:
Cell Death and Disease, Vol 13, Iss 2, Pp 1-3 (2022)
Externí odkaz:
https://doaj.org/article/e8d811ceb3704505869f8aa526a58052
Autor:
Zhuo Lin, Qian Xu, Xian Song, Yuan Zeng, Liuwei Zeng, Luying Zhao, Jun Xu, Dan Miao, Zhuoyan Chen, Fujun Yu
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundHepatocellular carcinoma (HCC) is a life-threatening and refractory malignancy with poor outcome. Genetic mutations are the hallmark of cancer. Thus far, there is no comprehensive prognostic model constructed by mutation-gene transcriptome
Externí odkaz:
https://doaj.org/article/d2d79a2f7ae242009bae344967b81cd6
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 17, Iss , Pp 235-244 (2019)
Small nuclear RNA host gene 7 (SNHG7), a novel long non-coding RNA (lncRNA), acts as an oncogene in cancers. However, whether SNHG7 is involved in hepatic stellate cell (HSC) activation during liver fibrosis is still unclear. In this study, upregulat
Externí odkaz:
https://doaj.org/article/79edd97358c6463d87fb3425dbe5b344
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundHepatocellular carcinoma (HCC) is a highly heterogeneous disease, which makes the prognostic prediction challenging. As part of the active cross-talk between the tumor and the host, inflammatory response in the tumor or its microenvironment
Externí odkaz:
https://doaj.org/article/e5d630d7aa23405da58c129af351ee8f
Publikováno v:
Cellular Physiology and Biochemistry, Vol 46, Iss 1, Pp 82-92 (2018)
Background/Aims: The activation of hepatic stellate cells (HSCs) is considered as a pivotal event in liver fibrosis and epithelial-mesenchymal transition (EMT) process has been reported to be involved in HSC activation. It is known that microRNAs (mi
Externí odkaz:
https://doaj.org/article/c2ac1e4d67f142aa83b69e26ffb8a8f8