Zobrazeno 1 - 10
of 391
pro vyhledávání: '"Fujun, Li"'
Publikováno v:
Shipin Kexue, Vol 45, Iss 20, Pp 280-289 (2024)
Protein ubiquitination, an important post-translational modification, plays a wide role in the life activities of eukaryotic cells. E3 ubiquitin ligases specifically recognize target proteins in the ubiquitin-proteasome degradation system and play a
Externí odkaz:
https://doaj.org/article/f7f4447229494da3930026e876733108
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-21 (2024)
Abstract Mitochondria, responsible for cellular energy synthesis and signal transduction, intricately regulate diverse metabolic processes, mediating fundamental biological phenomena such as cell growth, aging, and apoptosis. Tumor invasion and metas
Externí odkaz:
https://doaj.org/article/0783d75aa8f64fcdbeba3d2965acf060
Publikováno v:
Shipin Kexue, Vol 45, Iss 12, Pp 315-323 (2024)
The APETALA2/ethylene-responsive factor (AP2/ERF) transcription factor family is one of the largest transcription factor families in plants. Its subfamily members activate or repress the expression of related genes by specifically binding to cis-acti
Externí odkaz:
https://doaj.org/article/0a4ab35c0de84de092f998fa3b5fe869
Publikováno v:
Oncology Reviews, Vol 18 (2024)
Renal cell carcinoma (RCC) is one of the deadliest malignant tumors. Despite significant advances in RCC treatment over the past decade, complete remission is rarely achieved. Consequently, there is an urgent need to explore and develop new therapies
Externí odkaz:
https://doaj.org/article/129bd56d49ee4fe78ead1bcf1b4a8530
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Gene editing of living cells has become a crucial tool in medical research, enabling scientists to address fundamental biological questions and develop novel strategies for disease treatment. This technology has particularly revolutionized a
Externí odkaz:
https://doaj.org/article/72a5f87a160448cb8626c2ded775f7af
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
IntroductionPEDV, Brachyspira hyodysenteriae, and Lawsonia intracellularis, are highly contagious diarrheal pathogens that have caused significant harm to the global swine industry. Co-infections with multiple pathogens are common, making it challeng
Externí odkaz:
https://doaj.org/article/8d9ef091396546c19c12a7676e1406a9
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 8, p 285 (2024)
Background: Glioblastoma (GBM) is a highly aggressive and fast-growing brain tumor, characterized by rapid progression, a very poor prognosis, and a high likelihood of recurrence. Thus, effective new therapeutic targets are urgently needed. Transmemb
Externí odkaz:
https://doaj.org/article/23a1f130de1f478ca03fe71dea22c06f
Autor:
Sibel Ucpinar, Patrick F. Smith, Li Long, Fujun Li, Hui Yan, Jyoti Wadhwa, Katherine A. Chu, Jin Shu, Philip Nunn, Mengyao Li
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 7, Pp 1210-1219 (2023)
Abstract This single‐center, open‐label, non‐randomized, two‐part, phase I study was conducted (1) to evaluate the absolute oral bioavailability of rilzabrutinib 400 mg tablet following an i.v. microtracer dose of ~100 μg [14C]‐rilzabrutin
Externí odkaz:
https://doaj.org/article/e8f901b053fc4c77b57444a1f51b046f
Publikováno v:
Annals of Medicine, Vol 55, Iss 1 (2023)
AbstractObjective To investigate the predictive value of the prognostic nutritional index (PNI) for the effectiveness of infliximab (IFX) in patients with Crohn's disease (CD).Methods All data were retrospectively collected from Xiangya Hospital, Cen
Externí odkaz:
https://doaj.org/article/c8ae3b60704647239efc521c7a29914a
Publikováno v:
Technology in Cancer Research & Treatment, Vol 22 (2023)
With the progress of molecular diagnosis research on non-small cell lung cancer (NSCLC) cells, four identified categories of microRNAs have been found to be related to disease diagnosis, diagnosis of treatment resistance, prediction of prognosis, and
Externí odkaz:
https://doaj.org/article/5bd66364dcc64592a6b1c198951502d0