Tyrosine triple mutated AAV2-BDNF gene therapy in an inner retinal injury model induced by intravitreal injection of N -methyl-D-aspartate (NMDA).

Autor: Shiozawa AL; Department of Biochemistry and Molecular Biology, Nippon Medical School, Tokyo, Japan.; Department of Drug Discovery Research, Teika Pharmaceutical Co., Ltd., Toyama, Japan., Igarashi T; Department of Biochemistry and Molecular Biology, Nippon Medical School, Tokyo, Japan.; Department of Ophthalmology, Nippon Medical School, Tokyo, Japan., Kobayashi M; Department of Biochemistry and Molecular Biology, Nippon Medical School, Tokyo, Japan.; Department of Ophthalmology, Nippon Medical School, Tokyo, Japan., Nakamoto K; Department of Ophthalmology, Nippon Medical School, Tokyo, Japan., Kameya S; Department of Ophthalmology, Nippon Medical School Chiba Hokusoh Hospital, Chiba, Japan., Fujishita S; Department of Drug Discovery Research, Teika Pharmaceutical Co., Ltd., Toyama, Japan., Takahashi H; Department of Ophthalmology, Nippon Medical School, Tokyo, Japan., Okada T; Department of Biochemistry and Molecular Biology, Nippon Medical School, Tokyo, Japan.

Publikováno v: Molecular vision [Mol Vis] 2020 Jun 03; Vol. 26, pp. 409-422. Date of Electronic Publication: 2020 Jun 03 (Print Publication: 2020).

Funiculosin variants and phosphorylated derivatives promote innate immune responses via the Toll-like receptor 4/myeloid differentiation factor-2 complex.

Autor: Okamoto N; From the Department of Immunobiology and Pharmacological Genetics, Graduate School of Medicine and Pharmaceutical Science for Research, University of Toyama, 2630 Sugitani, Toyama-shi, Toyama 930-0194.; the Teika Pharmaceutical Co., Ltd., 1-3-27 Arakawa, Toyama-shi, Toyama 930-0982., Mizote K; the Laboratory of Natural Product Chemistry, Department of Chemistry, School of Science, Osaka University, 1-1 Machikaneyama, Toyonaka, Osaka 560-0043., Honda H; From the Department of Immunobiology and Pharmacological Genetics, Graduate School of Medicine and Pharmaceutical Science for Research, University of Toyama, 2630 Sugitani, Toyama-shi, Toyama 930-0194.; the Toyama Prefectural Institute for Pharmaceutical Research, 17-1 Nakataikouyama, Imizu City, Toyama 939-0363., Saeki A; the Laboratory of Natural Product Chemistry, Department of Chemistry, School of Science, Osaka University, 1-1 Machikaneyama, Toyonaka, Osaka 560-0043., Watanabe Y; From the Department of Immunobiology and Pharmacological Genetics, Graduate School of Medicine and Pharmaceutical Science for Research, University of Toyama, 2630 Sugitani, Toyama-shi, Toyama 930-0194., Yamaguchi-Miyamoto T; the Toyama Prefectural Institute for Pharmaceutical Research, 17-1 Nakataikouyama, Imizu City, Toyama 939-0363., Fukui R; the Division of Innate Immunity, Department of Microbiology and Immunology., Tanimura N; the Division of Innate Immunity, Department of Microbiology and Immunology., Motoi Y; the Division of Innate Immunity, Department of Microbiology and Immunology., Akashi-Takamura S; the Department of Microbiology and Immunology, School of Medicine, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi 480-1195., Kato T; the Teika Pharmaceutical Co., Ltd., 1-3-27 Arakawa, Toyama-shi, Toyama 930-0982., Fujishita S; the Teika Pharmaceutical Co., Ltd., 1-3-27 Arakawa, Toyama-shi, Toyama 930-0982., Kimura T; the Teika Pharmaceutical Co., Ltd., 1-3-27 Arakawa, Toyama-shi, Toyama 930-0982., Ohto U; the Graduate School of Pharmaceutical Sciences, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033., Shimizu T; the Graduate School of Pharmaceutical Sciences, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033., Hirokawa T; the Molecular Profiling Research Center for Drug Discovery, AIST, 2-3-26 Aomi, Koto-ku, Tokyo 135-0064.; the Division of Biomedical Science, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575., Miyake K; the Division of Innate Immunity, Department of Microbiology and Immunology.; the Laboratory of Innate Immunity, Center for Experimental Medicine and Systems Biology, Institute of Medical Science, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639., Fukase K; the Laboratory of Natural Product Chemistry, Department of Chemistry, School of Science, Osaka University, 1-1 Machikaneyama, Toyonaka, Osaka 560-0043., Fujimoto Y; the Japan Science and Technology Agency (JST), PRESTO, 4-1-8 Honcho, Kawaguchi, Saitama 332-0012, Japan., Nagai Y; From the Department of Immunobiology and Pharmacological Genetics, Graduate School of Medicine and Pharmaceutical Science for Research, University of Toyama, 2630 Sugitani, Toyama-shi, Toyama 930-0194, ynagai@med.u-toyama.ac.jp.; the Japan Science and Technology Agency (JST), PRESTO, 4-1-8 Honcho, Kawaguchi, Saitama 332-0012, Japan., Takatsu K; From the Department of Immunobiology and Pharmacological Genetics, Graduate School of Medicine and Pharmaceutical Science for Research, University of Toyama, 2630 Sugitani, Toyama-shi, Toyama 930-0194, takatsuk@med.u-toyama.ac.jp.; the Toyama Prefectural Institute for Pharmaceutical Research, 17-1 Nakataikouyama, Imizu City, Toyama 939-0363.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2017 Sep 15; Vol. 292 (37), pp. 15378-15394. Date of Electronic Publication: 2017 Jul 28.

Methodologies for specific intron and exon RNA localization in cultured cells by haptenized and fluorochromized probes

Autor: Dirks, R.W., van de Rijke, F.M., Fujishita, S., van der Ploeg, M., Raap, A.K.

Publikováno v: Journal of Cell Science; April 1993, Vol. 104 Issue: 4 p1187-1197, 11p

Effect of zwitterionic polymers on wound healing.

Autor: Fujishita S; Department of Applied Chemistry, Graduate School of Science and Engineering, University of Toyama, Japan., Inaba C, Tada S, Gemmei-Ide M, Kitano H, Saruwatari Y

Publikováno v: Biological & pharmaceutical bulletin [Biol Pharm Bull] 2008 Dec; Vol. 31 (12), pp. 2309-15.

Acquired idiopathic generalized anhidrosis with isolated sudomotor neuropathy.

Autor: Miyazoe S; Department of Neurology, Kawatana National Hospital, Nagasaki, Japan., Matsuo H, Ohnishi A, Tajima F, Fujishita S, Ichinose K, Shibuya N

Publikováno v: Annals of neurology [Ann Neurol] 1998 Sep; Vol. 44 (3), pp. 378-81.