Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Fujio, OKAMOTO"'
Autor:
Kimiko Ohgi, Hiroshi Kajiya, Kazuko Goto-T, Fujio Okamoto, Yasunori Yoshinaga, Koji Okabe, Ryuji Sakagami
Publikováno v:
Lipids in Health and Disease, Vol 17, Iss 1, Pp 1-9 (2018)
Abstract Background Lectin-like oxidized low-density-lipoprotein receptor 1 (Lox-1) is the receptor for oxidized low-density lipoprotein (oxLDL), a mediator in dyslipidemia. Toll-like receptor (TLR)-2 and − 4 are receptors of lipopolysaccharide (LP
Externí odkaz:
https://doaj.org/article/6ebd97ca2b7543728e04aefb55f1641b
Autor:
Masashi Shin, Aya Matsushima, Hiroshi Kajiya, Fujio Okamoto, Kayoko Ogata, Kyoko Oka, Hayato Ohshima, John D. Bartlett, Koji Okabe
Publikováno v:
European Journal of Oral Sciences. 131
Autor:
Masashi Shin, Shihomi Mori, Toshihide Mizoguchi, Atsushi Arai, Hiroshi Kajiya, Fujio Okamoto, John D. Bartlett, Masayuki Matsushita, Nobuyuki Udagawa, Koji Okabe
Publikováno v:
Bone. 166
Transient receptor potential melastatin-subfamily member 7 (TRPM7) is a bifunctional protein containing a kinase fused to an ion channel permeated with cations, including Ca
Autor:
Masao Ozaki, Koji Okabe, Fujio Okamoto, Tomoyuki Tsumuraya, Hiroshi Kajiya, Kayoko Ogata, Masashi Shin, Masayuki Matsushita, Kyoko Oka, Chiaki Katagiri
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Scientific Reports
Scientific Reports
Transient receptor potential melastatin-7 (TRPM7) is a bi-functional protein containing a kinase domain fused to an ion channel. TRPM7 is highly expressed in ameloblasts during tooth development. Here we show that TRPM7 kinase-inactive knock-in mutan
Autor:
Y. Yoshinaga, Ryuji Sakagami, Fujio Okamoto, Koji Okabe, Hiroshi Kajiya, Kazuko Goto-T, Kimiko Ohgi
Publikováno v:
Lipids in Health and Disease, Vol 17, Iss 1, Pp 1-9 (2018)
Lipids in Health and Disease
Lipids in Health and Disease
Background Lectin-like oxidized low-density-lipoprotein receptor 1 (Lox-1) is the receptor for oxidized low-density lipoprotein (oxLDL), a mediator in dyslipidemia. Toll-like receptor (TLR)-2 and − 4 are receptors of lipopolysaccharide (LPS) from P
Autor:
Koji Okabe, Tetsuomi Nemoto, Kazuko Toh-Goto, Shuji Nakayana, Hiroshi Kajiya, Keiichiro Kimachi, Fujio Okamoto
Publikováno v:
Cell Calcium. 48:260-269
The receptor activator of NFκB ligand (RANKL) induces Ca(2+) oscillations and activates the Nuclear Factor of Activated T cells 1 (NFATc1) during osteoclast differentiation (osteoclastogenesis). Ca(2+) oscillations are an important trigger signal fo
Autor:
Fujio Okamoto, Hiroshi Kajiya, Teruo Tanaka, Koji Okabe, Momono Yoshikawa, Shinichi Uchida, Mizuho A. Kido, Sei Sasaki, Kazuko Toh
Publikováno v:
American Journal of Physiology-Cell Physiology. 294:C693-C701
ClC-7 Cl− channels expressed in osteoclasts are important for bone resorption since it has been shown that disruption of the ClCN7 gene in mice leads to severe osteopetrosis. We have previously reported that Cl− currents recorded from mouse osteo
Publikováno v:
Endocrinology. 148:2116-2125
The plasma membrane Na(+)/Ca(2+) exchanger (NCX) is a bidirectional transporter that mediates the exchange of Na(+) for Ca(2+) depending on the electrochemical gradients. Mammalian NCXs form a multigene family comprising NCX1, NCX2, and NCX3 isoforms
Publikováno v:
Journal of Bone and Mineral Research. 21:984-992
To assess the role of Cl− transport during osteoclastic bone resorption, we studied the expression and function of K+/Cl− co-transporters (KCCs). KCC1 and chloride channel-7 were found to be expressed in mouse osteoclasts. The KCC inhibitor, R(+)
Publikováno v:
Bone. 36:267-275
Periodontitis, an inflammatory disorder of the supporting tissue of teeth, is one of the most common infectious diseases in humans. Periodontal pathogens promote inflammatory cytokines such as interleukin-1 (IL-1) and prostaglandin E2 (PGE2), resulti