Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Fujiang Xu"'
Autor:
Hailiang Zhang, Lin Bai, Xin-Qiang Wu, Xi Tian, Jinwen Feng, Xiaohui Wu, Guo-Hai Shi, Xiaoru Pei, Jiacheng Lyu, Guojian Yang, Yang Liu, Wenhao Xu, Aihetaimujiang Anwaier, Yu Zhu, Da-Long Cao, Fujiang Xu, Yue Wang, Hua-Lei Gan, Meng-Hong Sun, Jian-Yuan Zhao, Yuanyuan Qu, Dingwei Ye, Chen Ding
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract The tyrosine kinase inhibitor (TKI) Sunitinib is one the therapies approved for advanced renal cell carcinoma. Here, we undertake proteogenomic profiling of 115 tumors from patients with clear cell renal cell carcinoma (ccRCC) undergoing Sun
Externí odkaz:
https://doaj.org/article/8ad4bac66f634f059938ad9349903086
Autor:
Lingling Li, Dongxian Jiang, Qiao Zhang, Hui Liu, Fujiang Xu, Chunmei Guo, Zhaoyu Qin, Haixing Wang, Jinwen Feng, Yang Liu, Weijie Chen, Xue Zhang, Lin Bai, Sha Tian, Subei Tan, Chen Xu, Qi Song, Yalan Liu, Yunshi Zhong, Tianyin Chen, Pinghong Zhou, Jian-Yuan Zhao, Yingyong Hou, Chen Ding
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-28 (2023)
The progression of oesophageal squamous cell carcinoma (ESCC) from early to advanced stages requires comprehensive molecular characterisation. Here, the authors perform a proteogenomics analysis of ESCC patient samples across nine histopathological s
Externí odkaz:
https://doaj.org/article/4ad8acd2bf5b4a42988ddd5497c071cd
Autor:
Yuanyuan Qu, Xiaohui Wu, Aihetaimujiang Anwaier, Jinwen Feng, Wenhao Xu, Xiaoru Pei, Yu Zhu, Yang Liu, Lin Bai, Guojian Yang, Xi Tian, Jiaqi Su, Guo-Hai Shi, Da-Long Cao, Fujiang Xu, Yue Wang, Hua-Lei Gan, Shujuan Ni, Meng-Hong Sun, Jian-Yuan Zhao, Hailiang Zhang, Dingwei Ye, Chen Ding
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The molecular landscape of microphthalmia transcription factor family translocation renal cell carcinoma tumours remain to be characterised. Here, the authors perform proteogenomic analysis and reveal dysregulation of DNA repair, mTOR signalling and
Externí odkaz:
https://doaj.org/article/4e50108bebe8484ab0baed3796691570
Autor:
Yan Li, Chen Xu, Bing Wang, Fujiang Xu, Fahan Ma, Yuanyuan Qu, Dongxian Jiang, Kai Li, Jinwen Feng, Sha Tian, Xiaohui Wu, Yunzhi Wang, Yang Liu, Zhaoyu Qin, Yalan Liu, Jing Qin, Qi Song, Xiaolei Zhang, Akesu Sujie, Jie Huang, Tianshu Liu, Kuntang Shen, Jian-Yuan Zhao, Yingyong Hou, Chen Ding
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-26 (2022)
The mechanisms of resistance to therapy in gastric cancer remain to be explored. Here, proteomic profiling of 206 tumour tissues from patients treated with chemotherapy and anti-HER2-based therapy results in the identification of four molecular subty
Externí odkaz:
https://doaj.org/article/ace1bc4044db4255a59978634df01a76
Autor:
Ning Xu, Zhenmei Yao, Guoguo Shang, Dingwei Ye, Haixing Wang, Hailiang Zhang, Yuanyuan Qu, Fujiang Xu, Yunzhi Wang, Zhaoyu Qin, Jiajun Zhu, Fan Zhang, Jinwen Feng, Sha Tian, Yang Liu, Jianyuan Zhao, Jun Hou, Jianming Guo, Yingyong Hou, Chen Ding
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-39 (2022)
Abstract Background Urothelial carcinoma (UC) is the most common pathological type of bladder cancer, a malignant tumor. However, an integrated multi-omics analysis of the Chinese UC patient cohort is lacking. Methods We performed an integrated multi
Externí odkaz:
https://doaj.org/article/2f796f7d0cd448f991d646bb58de08b7
Autor:
Yuanyuan Qu, Jinwen Feng, Xiaohui Wu, Lin Bai, Wenhao Xu, Lingli Zhu, Yang Liu, Fujiang Xu, Xuan Zhang, Guojian Yang, Jiacheng Lv, Xiuping Chen, Guo-Hai Shi, Hong-Kai Wang, Da-Long Cao, Hang Xiang, Lingling Li, Subei Tan, Hua-Lei Gan, Meng-Hong Sun, Jiange Qiu, Hailiang Zhang, Jian-Yuan Zhao, Dingwei Ye, Chen Ding
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Clear cell renal cell carcinoma is an aggressive form of renal cancer, with differences in genomic mutations reported between Western and Eastern populations. In this study, the authors have compiled proteogenomic analysis of Chinese ccRCC to reveal
Externí odkaz:
https://doaj.org/article/b754924c3216474d8048ad77495d3428
Publikováno v:
Cancers, Vol 15, Iss 1, p 169 (2022)
Background: In the past decade, immunotherapy has been widely used in the treatment of various tumors, such as PD-1/PD-L1 inhibitors. Although clear cell renal cell carcinoma (ccRCC) has been shown to be sensitive to immunotherapy, it is effective on
Externí odkaz:
https://doaj.org/article/12a51b4c87ff4dff8f8127008cf4741b
Autor:
Yan Li, Chen Xu, Bing Wang, Fujiang Xu, Fahan Ma, Yuanyuan Qu, Dongxian Jiang, Kai Li, Jinwen Feng, Sha Tian, Xiaohui Wu, Yunzhi Wang, Yang Liu, Zhaoyu Qin, Yalan Liu, Jing Qin, Qi Song, Xiaolei Zhang, Akesu Sujie, Jie Huang, Tianshu Liu, Kuntang Shen, Jian-Yuan Zhao, Yingyong Hou, Chen Ding
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/97e94549b1ea42768620b141e9ee8141
Autor:
Jian Ma, Kun Chang, Jingtao Peng, Qing Shi, Hualei Gan, Kun Gao, Kai Feng, Fujiang Xu, Hailiang Zhang, Bo Dai, Yao Zhu, Guohai Shi, Yijun Shen, Yiping Zhu, Xiaojian Qin, Yao Li, Pingzhao Zhang, Dingwei Ye, Chenji Wang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-13 (2018)
Abstract Background Next-generation sequencing of the exome and genome of prostate cancers has identified numerous genetic alterations. SPOP (Speckle-type POZ Protein) is one of the most frequently mutated genes in primary prostate cancer, suggesting
Externí odkaz:
https://doaj.org/article/80d327e9cf0c497a9424b47a8fb0bd7f
Autor:
Lin Bai, Hou Yingyong, Qiao Zhang, Jian-Yuan Zhao, Dan Shen, Xue Zhang, Yang Liu, Sha Tian, Chen Ding, Hui Liu, Lingling Li, Fujiang Xu, Haixing Wang, Weijie Chen, Pinghong Zhou, Chen Xu, Dongxian Jiang, Jinwen Feng, Qi Song, Yalan Liu, Zhaoyu Qin, Subei Tan, Yun-Shi Zhong, T. Chen
Publikováno v:
Nature Communications. 14
Esophageal squamous cell carcinoma (ESCC) is malignant while the carcinogenesis is still unclear. Here, we perform a comprehensive multi-omics analysis of 786 trace-tumor-samples from 154 ESCC patients, covering 9 histopathological stages and 3 phase