Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Fuiboon Kai"'
Autor:
Elliot C Woods, FuiBoon Kai, J Matthew Barnes, Kayvon Pedram, Michael W Pickup, Michael J Hollander, Valerie M Weaver, Carolyn R Bertozzi
Publikováno v:
eLife, Vol 6 (2017)
Metastasis depends upon cancer cell growth and survival within the metastatic niche. Tumors which remodel their glycocalyces, by overexpressing bulky glycoproteins like mucins, exhibit a higher predisposition to metastasize, but the role of mucins in
Externí odkaz:
https://doaj.org/article/57d15b33b0224ade94a986318753f5e6
Publikováno v:
Molecular Biology of the Cell
Molecular Biology of the Cell, 2022, 33 (14), pp.br28. ⟨10.1091/mbc.E22-03-0092⟩
Molecular Biology of the Cell, 2022, 33 (14), pp.br28. ⟨10.1091/mbc.E22-03-0092⟩
International audience; Matrix stiffness and dimensionality have been shown to be major determinants of cell behavior. However, a workflow for examining nanometer-scale responses of the associated molecular machinery is not available. Here, we descri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9de62cb0c702af48ea673cccbfce57ff
https://hal.science/hal-04133460
https://hal.science/hal-04133460
Autor:
FuiBoon Kai, Guanqing Ou, Richard W Tourdot, Connor Stashko, Guido Gaietta, Mark F Swift, Niels Volkmann, Alexandra F Long, Yulong Han, Hector H Huang, Jason J Northey, Andrew M Leidal, Virgile Viasnoff, David M Bryant, Wei Guo, Arun P Wiita, Ming Guo, Sophie Dumont, Dorit Hanein, Ravi Radhakrishnan, Valerie M Weaver
Publikováno v:
The EMBO Journal. 41
Patient-derived organoids and cellular spheroids recapitulate tissue physiology with remarkable fidelity. We investigated how engagement with a reconstituted basement membrane in three dimensions (3D) supports the polarized, stress resilient tissue p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8521c25b6a5f48ddd107629b61e2a968
https://doi.org/10.15252/embj.2021109205
https://doi.org/10.15252/embj.2021109205
Autor:
Jason J. Northey, Yoshihiro Yui, Mary-Kate Hayward, Connor Stashko, FuiBoon Kai, Janna K. Mouw, Dhruv Thakar, Jonathon N. Lakins, Alastair J. Ironside, Susan Samson, Rita A. Mukhtar, E. Shelley Hwang, Valerie M Weaver
Tissue stem-progenitor cell frequency has been implicated in tumor risk and progression. Tissue-specific factors linking stem-progenitor cell frequency to cancer risk and progression remain ill defined. Using a genetically engineered mouse model that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7053cdd0eb2c282edc5d24c5f96a1a8
https://doi.org/10.1101/2022.04.19.487741
https://doi.org/10.1101/2022.04.19.487741
Autor:
Arun P. Wiita, Bryant Dm, Margaret Guo, Guanqing Ou, FuiBoon Kai, Wei Guo, Viasnoff, Sophie Dumont, Dorit Hanein, Ravi Radhakrishnan, Yisu Han, Alexandra F. Long, Hai Huang, Andrew M. Leidal, Valerie M. Weaver, Richard W. Tourdot, Niels Volkmann, Guido Gaietta, Mark F. Swift, Jason J. Northey, Connor Stashko
Primary tissue organoids and cell spheroids recapitulate tissue physiology with remarkable fidelity. We investigated how engagement with a three dimensional laminin-rich extracellular matrix supports the polarized, stress resilient spheroid phenotype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa1e3be97f3b2adb21e8286ebf08cec3
https://doi.org/10.1101/2021.07.14.452329
https://doi.org/10.1101/2021.07.14.452329
Autor:
Jason J. Northey, Yoshihiro Yui, Mary-Kate Hayward, Connor Stashko, FuiBoon Kai, Janna Mouw, Dhruv Thakar, Jonathon Lakins, Alastair Ironside, Susan Samson, Rita Mukhtar, E. Shelley Hwang, Valerie Weaver
Publikováno v:
Cancer Research. 82:LB021-LB021
Tissue stem-progenitor cell frequency has been implicated in tumor risk and progression. Tissue-specific factors linking stem-progenitor cell frequency to cancer risk and progression remain ill defined. Using a genetically engineered mouse model that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dd9b81042e82751c479abd5670073f0
https://doi.org/10.1158/1538-7445.am2022-lb021
https://doi.org/10.1158/1538-7445.am2022-lb021
Autor:
Matthew G. Rubashkin, Guanqing Ou, David J. Odde, Michael W. Davidson, Alexander R. Dunn, J. Matthew Barnes, Xin Ye, Jan Lammerding, Emily Bell, Alexandra L. McGregor, Louis S. Prahl, Christopher C. DuFort, Valerie M. Weaver, Steven Tan, Jonathan N. Lakins, Alice C. Chang, FuiBoon Kai, Armen H. Mekhdjian, Laralynne Przybyla, Luke Cassereau, Michael W. Pickup
Publikováno v:
Molecular Biology of the Cell
Molecular biology of the cell, vol 28, iss 11
Molecular biology of the cell, vol 28, iss 11
Mammary tumor cells adopt a basal-like phenotype when invading through a dense, stiffened, 3D matrix. These cells exert higher integrin-mediated traction forces, consistent with a physical motor-clutch model, display an altered molecular organization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fa5ffb4115b47a9324a3c6bf9543f97
http://europepmc.org/articles/PMC5449147
http://europepmc.org/articles/PMC5449147
Publikováno v:
Dev Cell
Developmental cell, vol 49, iss 3
Developmental cell, vol 49, iss 3
The extracellular matrix is perturbed in tumors. The tumor matrix promotes the growth, survival, and invasion of the cancer and modifies fibroblast and immune cell behavior to drive metastasis and impair treatment. Here, we discuss how the tumor matr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b55d80a0d4b2c30a6558500b13898ef
https://europepmc.org/articles/PMC6527347/
https://europepmc.org/articles/PMC6527347/
Autor:
J. Matthew Barnes, FuiBoon Kai, Valerie M. Weaver, Michael J. Hollander, Elliot C. Woods, Carolyn R. Bertozzi, Kayvon Pedram, Michael W. Pickup
Publikováno v:
eLife, Vol 6 (2017)
eLife
eLife
Metastasis depends upon cancer cell growth and survival within the metastatic niche. Tumors which remodel their glycocalyces, by overexpressing bulky glycoproteins like mucins, exhibit a higher predisposition to metastasize, but the role of mucins in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb32a4cee7866f2edcb8d653d8a321de
https://doi.org/10.7554/elife.25752
https://doi.org/10.7554/elife.25752
Autor:
Michael W. Pickup, Michael J. Hollander, J. Matthew Barnes, Carolyn R. Bertozzi, Elliot C. Woods, Valerie M. Weaver, Kayvon Pedram, FuiBoon Kai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbe1fbf1486274afa25ec8b180292b90
https://doi.org/10.7554/elife.25752.021
https://doi.org/10.7554/elife.25752.021