Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Fui-Teen Chong"'
Autor:
Joo-Leng Low, Dawn Pingxi Lau, Xiaoqian Zhang, Xue-Lin Kwang, Neha Rohatgi, Jane Vin Chan, Fui-Teen Chong, Stephen Qi Rong Wong, Hui-Sun Leong, Matan Thangavelu Thangavelu, Shivaji Rikka, Anders Martin Jacobsen Skanderup, Daniel Shao Weng Tan, Giridharan Periyasamy, Judice Lie Yong Koh, N Gopalakrishna Iyer, Ramanuj DasGupta
Publikováno v:
EBioMedicine, Vol 66, Iss , Pp 103297- (2021)
Externí odkaz:
https://doaj.org/article/efc7e7970bf04a188a2b4cbd40df635d
Autor:
Joo-Leng Low, Dawn Pingxi Lau, Xiaoqian Zhang, Xue-Lin Kwang, Neha Rohatgi, Jane Vin Chan, Fui-Teen Chong, Stephen Qi Rong Wong, Hui-Sun Leong, Matan Thangavelu Thangavelu, Shivaji Rikka, Anders Martin Jacobsen Skanderup, Daniel Shao Weng Tan, Giridharan Periyasamy, Judice Lie Yong Koh, N Gopalakrishna Iyer, Ramanuj DasGupta
Publikováno v:
EBioMedicine, Vol 64, Iss , Pp 103220- (2021)
Background: Overexpression of epidermal growth factor receptor (EGFR), and downstream pathway activation appears to be a common oncogenic driver in the majority of head and neck squamous cell cancers (HNSCCs); yet targeting EGFR for the treatment of
Externí odkaz:
https://doaj.org/article/a859aa922a95418fb03d43002f362811
Autor:
Shumei Chia, Joo-Leng Low, Xiaoqian Zhang, Xue-Lin Kwang, Fui-Teen Chong, Ankur Sharma, Denis Bertrand, Shen Yon Toh, Hui-Sun Leong, Matan T. Thangavelu, Jacqueline S. G. Hwang, Kok-Hing Lim, Thakshayeni Skanthakumar, Hiang-Khoon Tan, Yan Su, Siang Hui Choo, Hannes Hentze, Iain B. H. Tan, Alexander Lezhava, Patrick Tan, Daniel S. W. Tan, Giridharan Periyasamy, Judice L. Y. Koh, N. Gopalakrishna Iyer, Ramanuj DasGupta
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Treatment response in patient-derived models may serve as a biomarker for response in the clinic. Here, the authors use paired patient-derived mouse xenografts and patient-derived primary culture models from head and neck squamous cell carcinomas, in
Externí odkaz:
https://doaj.org/article/7f061de7c66f4a4eb132f00dff006462
Autor:
Hong Sheng Quah, Elaine Yiqun Cao, Lisda Suteja, Constance H. Li, Hui Sun Leong, Fui Teen Chong, Shilpi Gupta, Camille Arcinas, John F. Ouyang, Vivian Ang, Teja Celhar, Yunqian Zhao, Hui Chen Tay, Jerry Chan, Takeshi Takahashi, Daniel S. W. Tan, Subhra K. Biswas, Owen J. L. Rackham, N. Gopalakrishna Iyer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
The molecular mechanisms underlying lymph-node metastasis in head and neck squamous-cell carcinoma remain to be investigated. Here, the authors perform single-cell RNA sequencing of cancer cells and CD8 + T cells and suggest potential mechanisms of i
Externí odkaz:
https://doaj.org/article/38255f69fa6848db9cd30e34bbfaa608
Autor:
Fui Teen Chong, Alvin Wei Tian Ng, Szu-Chi Ho, Daniel Shao-Weng Tan, Willie Yu, N. Gopalakrishna Iyer, Arnoud Boot, Steven G. Rozen
Publikováno v:
Genome Res
Mutational signatures can reveal the history of mutagenic processes that cells were exposed to before and during tumorigenesis. We expect that as-yet-undiscovered mutational processes will shed further light on mutagenesis leading to carcinogenesis.
Autor:
Matan Thangavelu Thangavelu, Hui Min Vivian Teo, Fui Teen Chong, Jonathan R. Clark, Ankur Sharma, Ruta Gupta, Muhammad Hakimullah, Giridharan Periyasamy, Vibhor Kumar, Elaine Yiqun Cao, Xue Lin Kwang, Neeraja Ramakrishnan, Hui Sun Leong, Shumei Chia, N. Gopalakrishna Iyer, Angeline Mei Lin Wong, Xiaoqian Zhang, Ramanuj DasGupta
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Chemo-resistance is one of the major causes of cancer-related deaths. Here we used single-cell transcriptomics to investigate divergent modes of chemo-resistance in tumor cells. We observed that higher degree of phenotypic intra-tumor heterogeneity (
Autor:
Neha Rohatgi, Hui-Sun Leong, Anders Jacobsen Skanderup, Stephen Qi Rong Wong, Giridharan Periyasamy, Matan Thangavelu Thangavelu, Judice Lie Yong Koh, Fui-Teen Chong, Xiaoqian Zhang, Ramanuj DasGupta, N. Gopalakrishna Iyer, Dawn Pingxi Lau, Daniel Shao Weng Tan, Jane Vin Chan, Xue-Lin Kwang, Joo-Leng Low, Shivaji Rikka
Publikováno v:
EBioMedicine
EBioMedicine, Vol 64, Iss, Pp 103220-(2021)
EBioMedicine, Vol 64, Iss, Pp 103220-(2021)
Background Overexpression of epidermal growth factor receptor (EGFR), and downstream pathway activation appears to be a common oncogenic driver in the majority of head and neck squamous cell cancers (HNSCCs); yet targeting EGFR for the treatment of H
Autor:
Nicholas B. Shannon, Manikandan Lakshmanan, Jacqueline S.G. Hwang, Anandhkumar Raju, Kok Hing Lim, Dhivya Dadlani, Daniel Shao-Weng Tan, N. Gopalakrishna Iyer, Hui Sun Leong, Ern Yu Tan, Suhail Ahmed Kabeer Rasheed, Ravisankar Rajarethinam, Thakshayeni Skanthakumar, Vinay Tergaonkar, Paolo Ceppi, Patrick J. Casey, Fui-Teen Chong, Mei Wang
Publikováno v:
Oncogene
Treatment failure in solid tumors occurs due to the survival of specific subpopulations of cells that possess tumor-initiating (TIC) phenotypes. Studies have implicated G protein-coupled-receptors (GPCRs) in cancer progression and the acquisition of
Autor:
Patrick Tan, Giridharan Periyasamy, Matan Thangavelu Thangavelu, Judice L. Y. Koh, Hiang Khoon Tan, Shen Yon Toh, Daniel Shao-Weng Tan, Joo-Leng Low, Yan Su, Ankur Sharma, Thakshayeni Skanthakumar, Jacqueline S.G. Hwang, Alexander Lezhava, Iain Beehuat Tan, Hannes Hentze, Hui-Sun Leong, Shumei Chia, N. Gopalakrishna Iyer, Xue-Lin Kwang, Kok-Hing Lim, Xiaoqian Zhang, Ramanuj DasGupta, Siang Hui Choo, Fui-Teen Chong, Denis Bertrand
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Nature Communications
Nature Communications
Genomics-driven cancer therapeutics has gained prominence in personalized cancer treatment. However, its utility in indications lacking biomarker-driven treatment strategies remains limited. Here we present a “phenotype-driven precision-oncology”
Autor:
Tony Kiat Hon Lim, Chin-Ann Johnny Ong, Fui Teen Chong, Nicholas B. Shannon, Xuan Qiu, Daniel Shao-Weng Tan, Ke Li, Stefan Mueller, Gerald Tay, Jacqueline S.G. Hwang, Khee Chee Soo, Hiang Khoon Tan, Mei Kim Ang, Sze Min Lek, N. Gopalakrishna Iyer, Thakshayeni Skanthakumar, Kelvin K.N. Koh, Ngian-Chye Tan
Publikováno v:
Oncotarget
// Chin-Ann J. Ong 1, 3, * , Nicholas B. Shannon 2, * , Stefan Mueller 3, 7, * , Sze Min Lek 2, * , Xuan Qiu 1 , Fui Teen Chong 4 , Ke Li 2 , Kelvin K.N. Koh 2 , Gerald C.A. Tay 1, 7 , Thakshayeni Skanthakumar 3 , Jacqueline S.G. Hwang 5 , Tony Kiat