Výsledky vyhledávání - "Fui Leng Yan"

Akademický článek

Combination therapy with gossypol reveals synergism against gemcitabine resistance in cancer cells with high BCL-2 expression.

Autor: Foong Ying Wong, Natalia Liem, Chen Xie, Fui Leng Yan, Wing Cheong Wong, Lingzhi Wang, Wei-Peng Yong

Publikováno v: PLoS ONE, Vol 7, Iss 12, p e50786 (2012)

Although gemcitabine is highly active in several cancer types, intrinsic and acquired drug resistance remains a major challenge. Overexpression of Bcl-2 has been associated with gemcitabine resistance. The aim of this study is to determine whether go

Externí odkaz: https://doaj.org/article/f5c5027d887e4efabdbe7242f902ef83

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Supplementary Table S1 and Supplementary Figures S1 from ATM Expression Predicts Veliparib and Irinotecan Sensitivity in Gastric Cancer by Mediating P53-Independent Regulation of Cell Cycle and Apoptosis

Autor: Wei Peng Yong, Vaidehi Krishnan, Natalia Liem, Praveen C. Peethala, Fui Leng Yan, Mei Shi Yeo, Shi Hui Tan, Vinod Vijay Subhash

Table S1. Primers used to amplify ATM gene; Figure S1. siRNA knock down of ATM in HGC 27 cells.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aa776843d46e11e58dc84836c9d7968
https://doi.org/10.1158/1535-7163.22508752

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ATM Expression Predicts Veliparib and Irinotecan Sensitivity in Gastric Cancer by Mediating P53-Independent Regulation of Cell Cycle and Apoptosis

Autor: Wei Peng Yong, Shi Hui Tan, Fui Leng Yan, Mei Shi Yeo, Praveen C. Peethala, Natalia Liem, Vaidehi Krishnan, Vinod Vijay Subhash

Publikováno v: Molecular cancer therapeutics. 15(12)

Identification of synthetically lethal cellular targets and synergistic drug combinations is important in cancer chemotherapy as they help to overcome treatment resistance and increase efficacy. The Ataxia Telangiectasia Mutated (ATM) kinase is a nuc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98afed32e6bb1171467d0dba41c6bf52
https://pubmed.ncbi.nlm.nih.gov/27638859

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Loss of Melanoma-associated Antigen-A1 (MAGE-A1) Reverses Docetaxel Resistance and Increases Apoptosis via p53-independent Pathway in Gastric Cancer

Autor: Natalia Liem, Chen Xie, Foong Ying Wong, Fui Leng Yan, Wei Peng Yong

Publikováno v: Journal of Carcinogenesis & Mutagenesis.

Melanoma Associated Antigen (MAGE)-encoding genes have been shown to be aberrantly expressed in various tumour types, and correlate with tumour progression and resistance to docetaxel. The objective of this study was to elucidate the regulatory mecha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8e095302644cb59a0a5aa7abd6787450
https://doi.org/10.4172/2157-2518.s6-006

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Combination Therapy with Gossypol Reveals Synergism against Gemcitabine Resistance in Cancer Cells with High BCL-2 Expression

Autor: Fui Leng Yan, Lingzhi Wang, Wei Peng Yong, Foong Ying Wong, Chen Xie, Natalia Liem, Wing-Cheong Wong

Publikováno v: PLoS ONE
PLoS ONE, Vol 7, Iss 12, p e50786 (2012)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2313c239b4d05f8e2da2e13f36d49260
http://europepmc.org/articles/PMC3514173

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Abstract 4937: Atm expression predicts ABT-888 and CPT-11 sensitivity in gastric cancer cells by mediating p53 independent regulation of cell cycle and apoptosis

Autor: Fui Leng Yan, Shihui Tan, Wei Peng Yong, Vinod Vijayasubhash, Natalia Liem

Publikováno v: Cancer Research. 76:4937-4937

Background: Identification of synthetically lethal cellular targets and synergistic drug combinations are important in cancer chemo therapy as they help to overcome treatment resistance and increase efficacy. The Ataxia Telangiectasia Mutated (ATM) k

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6a791708db50d598ad2de686e774c0cb
https://doi.org/10.1158/1538-7445.am2016-4937

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