Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Fui G. Goh"'
Autor:
David G. Saliba, Andreas Heger, Hayley L. Eames, Spyros Oikonomopoulos, Ana Teixeira, Katrina Blazek, Ariadne Androulidaki, Daniel Wong, Fui G. Goh, Miriam Weiss, Adam Byrne, Manolis Pasparakis, Jiannis Ragoussis, Irina A. Udalova
Publikováno v:
Cell Reports, Vol 8, Iss 5, Pp 1308-1317 (2014)
Interferon Regulatory Factor 5 (IRF5) plays a major role in setting up an inflammatory macrophage phenotype, but the molecular basis of its transcriptional activity is not fully understood. In this study, we conduct a comprehensive genome-wide analys
Externí odkaz:
https://doaj.org/article/62176b6cba9e405491e69a22de5b11c8
Autor:
Alessandra Lanfrancotti, Richard R. Copley, Scott J. P. Thomson, Fui G. Goh, Thomas Krausgruber, Irina A. Udalova
Publikováno v:
Blood; Vol 116
The expression of interferon-β (IFN-β) in virus-infected HeLa cells established a paradigm of multifactorial gene regulation, in which cooperative assembly of transcription factors (TFs) at the composite DNA element (enhanceosome), is central for a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55f6f57ef74f3c89502cd480a86021bd
Autor:
Daniel Wong, Fui G. Goh, Jiannis Ragoussis, Andreas Heger, Spyros Oikonomopoulos, David Saliba, Ariadne Androulidaki, Miriam Weiss, Hayley L. Eames, Katrina Blazek, Adam J. Byrne, Manolis Pasparakis, Ana Teixeira, Irina A. Udalova
Publikováno v:
Cell Reports
Cell Reports, Vol 8, Iss 5, Pp 1308-1317 (2014)
Cell Reports, Vol 8, Iss 5, Pp 1308-1317 (2014)
Summary Interferon Regulatory Factor 5 (IRF5) plays a major role in setting up an inflammatory macrophage phenotype, but the molecular basis of its transcriptional activity is not fully understood. In this study, we conduct a comprehensive genome-wid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b674188da0e63771c13d9e8084db52e0
http://ora.ox.ac.uk/objects/uuid:090364ec-e993-4a83-b0a1-482aa66dd0f8
http://ora.ox.ac.uk/objects/uuid:090364ec-e993-4a83-b0a1-482aa66dd0f8
Autor:
Fui G. Goh, Kim S. Midwood
Publikováno v:
Rheumatology (Oxford, England). 51(1)
RA is a debilitating disorder that manifests as chronic localized synovial and systemic inflammation leading to progressive joint destruction. Recent advances in the molecular basis of RA highlight the role of both the innate and adaptive immune syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c3a5ceea5d911d13a51a5c5be605b1f
https://pubmed.ncbi.nlm.nih.gov/21984766
https://pubmed.ncbi.nlm.nih.gov/21984766
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 184(5)
Inappropriate expression of proinflammatory mediators underpins the pathogenesis of autoimmune disease and tumor metastasis. The extracellular matrix glycoprotein tenascin-C is an endogenous activator of innate immunity that promotes the synthesis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d7b3eb0366a3aedc082f746c9855b84
https://pubmed.ncbi.nlm.nih.gov/20107185
https://pubmed.ncbi.nlm.nih.gov/20107185
Autor:
Scott J. P. Thomson, Thomas Krausgruber, Irina A. Udalova, Sergei V. Kotenko, Helen Banks, Brian M. J. Foxwell, Fui G. Goh
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 106(28)
IFNs lambda1, lambda2, and lambda3, or type III IFNs, are recently identified cytokines distantly related to type I IFNs. Despite an early evolutionary divergence, the 2 types of IFNs display similar antiviral activities, and both are produced primar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35213d1cb0d962d75ad7b5b7c2505d61
https://pubmed.ncbi.nlm.nih.gov/19570999
https://pubmed.ncbi.nlm.nih.gov/19570999
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 512
NF-kappaB plays a pivotal role in immunity and inflammation and is considered to be a promising candidate for drug development. However, global suppression of NF-kappaB may have undesirable side-effects. Our data and the results of others suggest tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dc070c77ac2ac49574c97b81c30ed5eb
https://pubmed.ncbi.nlm.nih.gov/19347272
https://pubmed.ncbi.nlm.nih.gov/19347272
Publikováno v:
Methods in Molecular Biology™ ISBN: 9781603275293
NF-kappaB plays a pivotal role in immunity and inflammation and is considered to be a promising candidate for drug development. However, global suppression of NF-kappaB may have undesirable side-effects. Our data and the results of others suggest tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eec2af496654bbed088f527ea9edcbe
https://doi.org/10.1007/978-1-60327-530-9_4
https://doi.org/10.1007/978-1-60327-530-9_4
