Zobrazeno 1 - 10
of 422
pro vyhledávání: '"Fuhai LI"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 27, Iss , Pp 32-34 (2025)
In this editorial, we summarize the 2023 International Conference on Intelligent Biology and Medicine (ICIBM 2023) conference which was held on July 16–19, 2023 in Tampa, Florida, USA. We then briefly describe the nine research articles included in
Externí odkaz:
https://doaj.org/article/d09fe3e1add345eba670a9a638e8c9f5
Publikováno v:
npj Systems Biology and Applications, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract Complex signaling pathways are believed to be responsible for drug resistance. Drug combinations perturbing multiple signaling targets have the potential to reduce drug resistance. The large-scale multi-omic datasets and experimental drug co
Externí odkaz:
https://doaj.org/article/9d2e9589e46548c9993fa78d2429b546
Publikováno v:
BMC Cardiovascular Disorders, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background Left ventricular thrombus (LVT) is a serious complication after myocardial infarction. However, due to its asymptomatic nature, early detection is challenging. We aimed to explore the differences in clinical correlates of LVT foun
Externí odkaz:
https://doaj.org/article/1ab9fa5863f043f3b322dae7147b24f8
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
Barth syndrome (BTHS) is a rare X-linked recessive genetic disorder characterized by a broad spectrum of clinical features including cardiomyopathy, skeletal myopathy, neutropenia, growth delay, and 3-methylglutaconic aciduria. This disease is caused
Externí odkaz:
https://doaj.org/article/c924f3763e0943468be6416a2682d174
Autor:
Jiarui Feng, Haoran Song, Michael Province, Guangfu Li, Philip R. O. Payne, Yixin Chen, Fuhai Li
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Recently, large-scale scRNA-seq datasets have been generated to understand the complex signaling mechanisms within the microenvironment of Alzheimer’s Disease (AD), which are critical for identifying novel therapeutic targets and precision medicine
Externí odkaz:
https://doaj.org/article/d501505450194e8a8ab745654a7e2de7
Autor:
Lihua Wang, Niko-Petteri Nykänen, Daniel Western, Priyanka Gorijala, Jigyasha Timsina, Fuhai Li, Zhaohua Wang, Muhammad Ali, Chengran Yang, Menghan Liu, William Brock, Marta Marquié, Mercè Boada, Ignacio Alvarez, Miquel Aguilar, Pau Pastor, Agustín Ruiz, Raquel Puerta, Adelina Orellana, Jarod Rutledge, Hamilton Oh, Michael D Greicius, Yann Le Guen, Richard J. Perrin, Tony Wyss-Coray, Angela Jefferson, Timothy J. Hohman, Neill Graff-Radford, Hiroshi Mori, Alison Goate, Johannes Levin, Yun Ju Sung, Carlos Cruchaga
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-25 (2024)
Abstract Triggering receptor expressed on myeloid cells 2 (TREM2) plays a critical role in microglial activation, survival, and apoptosis, as well as in Alzheimer’s disease (AD) pathogenesis. We previously reported the MS4A locus as a key modulator
Externí odkaz:
https://doaj.org/article/7186895a6614490394229c23126dc1de
Autor:
Mengqi Guo, Zongyi Xia, Yefeng Hong, Hongwei Ji, Fuhai Li, Wenheng Liu, Shaohua Li, Hui Xin, Kai Tan, Zhexun Lian
Publikováno v:
Journal of Inflammation, Vol 20, Iss 1, Pp 1-15 (2023)
Abstract Background Diabetes mellitus is one of the causes of poor ventricular remodelling and poor cardiac recovery after myocardial infarction (MI). We previously reported that tissue factor pathway inhibitor-2 (TFPI2) was downregulated in response
Externí odkaz:
https://doaj.org/article/2037813727224ef1a505212da05e61ea
Publikováno v:
AIMS Molecular Science, Vol 10, Iss 3, Pp 153-170 (2023)
Amines are abundant in natural product chemistry and are readily available chemical raw materials. The C-N bonds of amines are difficult to break due to the large C-N bond energy. In recent years, chemists have developed a variety of activation metho
Externí odkaz:
https://doaj.org/article/bd6aa5a7714a4acd818e71e6440b6de0
Publikováno v:
Advances in Civil Engineering, Vol 2024 (2024)
The utilization of recycled aggregate can significantly mitigate the extraction of natural sand and gravel. However, the practical application of recycled aggregate in engineering is impeded by its inherent characteristics, encompassing high water ab
Externí odkaz:
https://doaj.org/article/07494f156f00446c9aafe26c9623dbc3
Autor:
Jiarui Feng, S Peter Goedegebuure, Amanda Zeng, Ye Bi, Ting Wang, Philip Payne, Li Ding, David DeNardo, William Hawkins, Ryan C Fields, Fuhai Li
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 1, p e1011785 (2024)
Single-cell RNA sequencing (scRNA-seq) is a powerful technology to investigate the transcriptional programs in stromal, immune, and disease cells, like tumor cells or neurons within the Alzheimer's Disease (AD) brain or tumor microenvironment (ME) or
Externí odkaz:
https://doaj.org/article/8803c78ee8174e8c9d10b0eabfe098d4