Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Fuguo Wu"'
Autor:
Todd McLaughlin, Jinli Wang, Liyun Jia, Fuguo Wu, Yaqin Wang, Joshua J. Wang, Xiuqian Mu, Sarah X. Zhang
Publikováno v:
Cells, Vol 12, Iss 12, p 1558 (2023)
p58IPK is a multifaceted endoplasmic reticulum (ER) chaperone and a regulator of eIF2α kinases involved in a wide range of cellular processes including protein synthesis, ER stress response, and macrophage-mediated inflammation. Systemic deletion of
Externí odkaz:
https://doaj.org/article/48ecd1f9bfd44090a3e71d17a4fe9acc
Autor:
Fuguo Wu, Jonathan E. Bard, Julien Kann, Donald Yergeau, Darshan Sapkota, Yichen Ge, Zihua Hu, Jie Wang, Tao Liu, Xiuqian Mu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Atoh7 is essential for retinal ganglion cell (RGC) genesis. Here the authors perform scRNAseq on embryonic mouse retina and conclude that Atoh7 defines a transitional state and that other factors also participate in establishing the RGC lineage.
Externí odkaz:
https://doaj.org/article/6e196bf549b6423fb0b29df0f5c27a2e
Autor:
Sriganesh Ramachandra Rao, Lara A. Skelton, Fuguo Wu, Agnieszka Onysk, Grzegorz Spolnik, Witold Danikiewicz, Mark C. Butler, Delores A. Stacks, Liliana Surmacz, Xiuqian Mu, Ewa Swiezewska, Steven J. Pittler, Steven J. Fliesler
Publikováno v:
iScience, Vol 23, Iss 6, Pp 101198- (2020)
Summary: Dehydrodolichyl diphosphate synthase (DHDDS) catalyzes the committed step in dolichol synthesis. Recessive mutations in DHDDS cause retinitis pigmentosa (RP59), resulting in blindness. We hypothesized that rod photoreceptor-specific ablation
Externí odkaz:
https://doaj.org/article/81a55c7b9d8749cbbf5fd2924ed7aa4e
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92105 (2014)
Precise regulation of gene expression during biological processes, including development, is often achieved by combinatorial action of multiple transcription factors. The mechanisms by which these factors collaborate are largely not known. We have sh
Externí odkaz:
https://doaj.org/article/2f17c8aad587459fb8a304bdb40b0273
Autor:
Zhang, Todd McLaughlin, Jinli Wang, Liyun Jia, Fuguo Wu, Yaqin Wang, Joshua J. Wang, Xiuqian Mu, Sarah X.
Publikováno v:
Cells; Volume 12; Issue 12; Pages: 1558
p58IPK is a multifaceted endoplasmic reticulum (ER) chaperone and a regulator of eIF2α kinases involved in a wide range of cellular processes including protein synthesis, ER stress response, and macrophage-mediated inflammation. Systemic deletion of
Autor:
Yichen Ge, Xushen Chen, Nan Nan, Jonathan Bard, Fuguo Wu, Donald Yergeau, Tao Liu, Jie Wang, Xiuqian Mu
How the diverse neural cell types emerge from multipotent neural progenitor cells during central nervous system development remains poorly understood. Recent scRNA-seq studies have delineated the developmental trajectories of individual neural cell t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c461d9c5fd8c73efd64093b4750381f
https://doi.org/10.1101/2022.03.05.483140
https://doi.org/10.1101/2022.03.05.483140
Publikováno v:
Dev Dyn
Background During development, all retinal cell types arise from retinal progenitor cells (RPCs) in a step-wise fashion. Atoh7 and Pou4f2 mark, and function in, two phases of retinal ganglion cell (RGC) genesis; Atoh7 functions in a subpopulation of
Autor:
Leo Speidel, Omer Gokcumen, Shigeki Nakagome, Qihui Zhu, Laura G. Reinholdt, Fuguo Wu, Gary A. Churchill, Nancy J. Hall, Yoko Satta, Neil A. Hanchard, Skyler Resendez, Natasha C. Lie, G. Ekin Atilla-Gokcumen, Apoorva J Pradhan, Charles Lee, Xiuqian Mu, Marie Saitou
Publikováno v:
Science Advances
Description
The evolutionary history of a common genetic variant is linked to its sex-specific effect on response to nutritional stress.
The common deletion of the third exon of the growth hormone receptor gene (GHRd3) in humans is associat
The evolutionary history of a common genetic variant is linked to its sex-specific effect on response to nutritional stress.
The common deletion of the third exon of the growth hormone receptor gene (GHRd3) in humans is associat
Autor:
Tadeusz J. Kaczynski, Tao Liu, Martin R Turner, Fuguo Wu, Louise S. Matheson, Jie Wang, Xiuqian Mu
Both transcriptional and post-transcriptional regulation of gene expression play significant roles in diverse biological processes, but little is known about how post-transcriptional regulation impacts retinal development. Here we report our study of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cb915a2edc421cf89d5884f922ce8fa
https://doi.org/10.1101/2020.12.15.422926
https://doi.org/10.1101/2020.12.15.422926
Autor:
Mark C. Butler, Sriganesh Ramachandra Rao, Delores A. Stacks, Agnieszka Onysk, Fuguo Wu, Liliana Surmacz, Lara A. Skelton, Xiuqian Mu, Steven J. Fliesler, Ewa Swiezewska, Witold Danikiewicz, Steven J. Pittler, Grzegorz Spólnik
Publikováno v:
iScience, Vol 23, Iss 6, Pp 101198-(2020)
iScience
iScience
Summary Dehydrodolichyl diphosphate synthase (DHDDS) catalyzes the committed step in dolichol synthesis. Recessive mutations in DHDDS cause retinitis pigmentosa (RP59), resulting in blindness. We hypothesized that rod photoreceptor-specific ablation