Cell Senescence-Related Pathways Are Enriched in Breast Cancer Patients With Late Toxicity After Radiotherapy and Low Radiation-Induced Lymphocyte Apoptosis.

Autor: Aguado-Flor E; Hereditary Cancer Genetics Group, Vall d'Hebron Institute of Oncology (VHIO), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain., Fuentes-Raspall MJ; Radiation Oncology Department, Santa Creu i Sant Pau Hospital, Barcelona, Spain., Gonzalo R; Statistics and Bioinformatics Unit, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain., Alonso C; Medical Oncology Department, Santa Creu i Sant Pau Hospital, Barcelona, Spain., Ramón Y Cajal T; Medical Oncology Department, Santa Creu i Sant Pau Hospital, Barcelona, Spain., Fisas D; Medical Oncology Department, Santa Creu i Sant Pau Hospital, Barcelona, Spain., Seoane A; Medical Physics Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain., Sánchez-Pla Á; Statistics and Bioinformatics Unit, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.; Genetics, Microbiology and Statistics Department, Universitat de Barcelona, Barcelona, Spain., Giralt J; Radiation Oncology Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.; Radiation Oncology Group, Vall d'Hebron Institute of Oncology (VHIO), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain., Díez O; Hereditary Cancer Genetics Group, Vall d'Hebron Institute of Oncology (VHIO), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.; Area of Clinical and Molecular Genetics, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain., Gutiérrez-Enríquez S; Hereditary Cancer Genetics Group, Vall d'Hebron Institute of Oncology (VHIO), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.

Publikováno v: Frontiers in oncology [Front Oncol] 2022 May 24; Vol. 12, pp. 825703. Date of Electronic Publication: 2022 May 24 (Print Publication: 2022).

Individual patient data meta-analysis shows a significant association between the ATM rs1801516 SNP and toxicity after radiotherapy in 5456 breast and prostate cancer patients.

Autor: Andreassen CN; Department of Experimental Clinical Oncology, Aarhus University Hospital, Denmark. Electronic address: nicolaj@oncology.au.dk., Rosenstein BS; Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, USA., Kerns SL; Department of Radiation Oncology, University of Rochester Medical Center, USA; Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, USA., Ostrer H; Departments of Pathology and Pediatrics, Albert Einstein College of Medicine, New York, USA., De Ruysscher D; Department of Radiotherapy (Maastro Clinic), Maastricht University Medical Center, The Netherlands., Cesaretti JA; Southpoint Cancer Center, Jacksonville, USA., Barnett GC; Department of Oncology, Cambridge University Hospitals NHS Foundation Trust, UK; Centre for Cancer Genetic Epidemiology, Strangeways Research Laboratory, University of Cambridge, UK., Dunning AM; Department of Oncology, Cambridge University Hospitals NHS Foundation Trust, UK; Centre for Cancer Genetic Epidemiology, Strangeways Research Laboratory, University of Cambridge, UK., Dorling L; Centre for Cancer Genetic Epidemiology, Strangeways Research Laboratory, University of Cambridge, UK., West CML; Institute of Cancer Sciences, University of Manchester, The Christie NHS Foundation Trust, UK., Burnet NG; Department of Oncology, Cambridge University Hospitals NHS Foundation Trust, UK., Elliott R; Department of Oncology, Cambridge University Hospitals NHS Foundation Trust, UK., Coles C; Department of Oncology, Cambridge University Hospitals NHS Foundation Trust, UK., Hall E; Clinical Trials & Statistics Unit (ICR-CTSU), The Institute of Cancer Research, London, UK., Fachal L; Fundacion Publica Galega de Medicina Xenomica-SERGAS, Grupo de Medicina Xenomica-USC, IDIS, CIBERER, Santiago de Compostela, Spain., Vega A; Fundacion Publica Galega de Medicina Xenomica-SERGAS, Grupo de Medicina Xenomica-USC, IDIS, CIBERER, Santiago de Compostela, Spain., Gómez-Caamaño A; Department of Radiation Oncology, Complexo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain., Talbot CJ; Department of Genetics, University of Leicester, UK., Symonds RP; Department of Cancer Studies, University of Leicester, UK., De Ruyck K; Department of Basic Medical Sciences, Ghent University, Belgium., Thierens H; Department of Basic Medical Sciences, Ghent University, Belgium., Ost P; Department of Radiotherapy, Ghent University Hospital, Belgium., Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany; University Cancer Center Hamburg, University (UCCH), University Medical Center Hamburg-Eppendorf, Germany., Seibold P; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Popanda O; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany., Overgaard M; Department of Experimental Clinical Oncology, Aarhus University Hospital, Denmark., Dearnaley D; The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, London, UK., Sydes MR; MRC Clinical Trials Unit at UCL, London, UK., Azria D; Department of Radiation Oncology and Medical Physics, Institut regional du Cancer Montpellier, France., Koch CA; Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada., Parliament M; Department of Oncology, Cross Cancer Institute, University of Alberta, Edmonton, Canada., Blackshaw M; Department of Oncology, Cross Cancer Institute, University of Alberta, Edmonton, Canada., Sia M; Department of Radiation Oncology, British Columbia Cancer Agency Abbotsford Clinic, Canada., Fuentes-Raspall MJ; Department of Radiation Oncology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain., Ramon Y Cajal T; Medical Oncology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain., Barnadas A; Medical Oncology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain., Vesprini D; Department of Radiation Oncology, Sunnybrook Health Sciences Centre, Toronto, Canada., Gutiérrez-Enríquez S; Oncogenetics Group, Vall d'Hebron Institute of Oncology (VHIO), Universitat Autònoma de Barcelona, Spain., Mollà M; Department of Radiation Oncology, Vall d'Hebron University Hospital, Barcelona, Spain., Díez O; Oncogenetics Group, Vall d'Hebron Institute of Oncology (VHIO), Area of Clinical and Molecular Genetics, Vall d'Hebron University Hospital, Barcelona, Spain., Yarnold JR; The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, London, UK., Overgaard J; Department of Experimental Clinical Oncology, Aarhus University Hospital, Denmark., Bentzen SM; Greenebaum Cancer Center and Department of Epidemiology & Public Health, University of Maryland School of Medicine, Baltimore, USA., Alsner J; Department of Experimental Clinical Oncology, Aarhus University Hospital, Denmark.

Publikováno v: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology [Radiother Oncol] 2016 Dec; Vol. 121 (3), pp. 431-439. Date of Electronic Publication: 2016 Jul 18.

Individual patient data meta-analysis shows no association between the SNP rs1800469 in TGFB and late radiotherapy toxicity.

Autor: Barnett GC; Cambridge University Hospital NHS Foundation Trust, UK. gillbarnett@doctors.org.uk, Elliott RM, Alsner J, Andreassen CN, Abdelhay O, Burnet NG, Chang-Claude J, Coles CE, Gutiérrez-Enríquez S, Fuentes-Raspall MJ, Alonso-Muñoz MC, Kerns S, Raabe A, Symonds RP, Seibold P, Talbot CJ, Wenz F, Wilkinson J, Yarnold J, Dunning AM, Rosenstein BS, West CM, Bentzen SM

Publikováno v: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology [Radiother Oncol] 2012 Dec; Vol. 105 (3), pp. 289-95. Date of Electronic Publication: 2012 Nov 28.

[Locoregional recurrences after conservative treatment of breast cancer stage I-II].

Autor: Fuentes Raspall MJ; Oncología Radioterápica. Hospital de la Santa Creu i Sant Pau. Barcelona. Spain. mfuentesr@hsp.santpau.es, Piedrafita Serra E, Isern Verdum J, Alonso Muñoz C, Ojeda González B, Gómez Gómez A, Llauradó Ollé A, Duarte Pires D, Lerma Puertas E, Craven-Bartle Lamote De Grignon J, López López A, Trias Folch M

Publikováno v: Medicina clinica [Med Clin (Barc)] 2002 Feb 16; Vol. 118 (5), pp. 161-5.