Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Fuentes-Iglesias A"'
Autor:
Guallar, Diana, Fuentes-Iglesias, Alejandro, Souto, Yara, Ameneiro, Cristina, Freire-Agulleiro, Oscar, Pardavila, Jose Angel, Escudero, Adriana, Garcia-Outeiral, Vera, Moreira, Tiago, Saenz, Carmen, Xiong, Heng, Liu, Dongbing, Xiao, Shidi, Hou, Yong, Wu, Kui, Torrecilla, Daniel, Hartner, Jochen C., Blanco, Miguel G., Lee, Leo J., López, Miguel, Walkley, Carl R., Wang, Jianlong, Fidalgo, Miguel
Publikováno v:
In Cell Stem Cell 6 August 2020 27(2):300-314
Autor:
Jie Lan, Nicholas Rajan, Martin Bizet, Audrey Penning, Nitesh K. Singh, Diana Guallar, Emilie Calonne, Andrea Li Greci, Elise Bonvin, Rachel Deplus, Phillip J. Hsu, Sigrid Nachtergaele, Chengjie Ma, Renhua Song, Alejandro Fuentes-Iglesias, Bouchra Hassabi, Pascale Putmans, Frédérique Mies, Gerben Menschaert, Justin J. L. Wong, Jianlong Wang, Miguel Fidalgo, Bifeng Yuan, François Fuks
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
TET mediated RNA-hydroxymethylation (5hmC) has been detected in mammals, but its physiological role remains unclear. Here the authors map 5hmC during embryonic stem cell (ESC) differentiation and find that Tet-mediated RNA hydroxymethylation reduces
Externí odkaz:
https://doaj.org/article/9305faa1ca904cdba667b6f5f1a6c75f
Autor:
Alejandro Fuentes-Iglesias, Vera Garcia-Outeiral, Jose Angel Pardavila, Jianlong Wang, Miguel Fidalgo, Diana Guallar
Publikováno v:
STAR Protocols, Vol 1, Iss 2, Pp 100093- (2020)
Summary: RNA-binding proteins are key regulators of cell identity and function, which underscores the need for unbiased and versatile protocols to identify and characterize novel protein-RNA interactions. Here, we describe a simple and cost-effective
Externí odkaz:
https://doaj.org/article/66f87f956af94b8b81d07f6132fadaeb
Autor:
Fuentes Iglesias, Alejandro
Whereas RNA editing of adenosine-to-inosine (A-to-I) catalyzed by ADAR proteins is intricately linked to transcriptome structural and functional diversity, how this RNA chemical modification contributes to overriding somatic cell identity during repr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1601::0d4da259b66a16b5475ba786666a3b48
https://hdl.handle.net/10347/30317
https://hdl.handle.net/10347/30317
Akademický článek
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Autor:
Cheng-Jie Ma, Sigrid Nachtergaele, Nitesh Kumar Singh, Nicholas Rajan, Gerben Menschaert, Miguel Fidalgo, Martin Bizet, Jianlong Wang, Bouchra Hassabi, Andrea Li Greci, Elise Bonvin, François Fuks, Pascale Putmans, Emilie Calonne, Bi-Feng Yuan, Diana Guallar, Alejandro Fuentes-Iglesias, Phillip J. Hsu, Renhua Song, Rachel Deplus, Audrey Penning, Justin J.-L. Wong, Jie Lan, Frédérique Mies
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
NATURE COMMUNICATIONS
Nature Communications
Nature communications, 11 (1
NATURE COMMUNICATIONS
Nature Communications
Nature communications, 11 (1
Tet-enzyme-mediated 5-hydroxymethylation of cytosines in DNA plays a crucial role in mouse embryonic stem cells (ESCs). In RNA also, 5-hydroxymethylcytosine (5hmC) has recently been evidenced, but its physiological roles are still largely unknown. He
Autor:
Vikas Malik, Ruge Zang, Alejandro Fuentes-Iglesias, Xin Huang, Dan Li, Miguel Fidalgo, Hongwei Zhou, Jianlong Wang
Publikováno v:
Life Science Alliance. 5:e202201608
Extended pluripotent or expanded potential stem cells (EPSCs) possess superior developmental potential to embryonic stem cells (ESCs). However, the molecular underpinning of EPSC maintenance in vitro is not well defined. We comparatively studied tran
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2454
The reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) has proven to be a powerful system creating new opportunities to interrogate molecular mechanisms controlling cell fate determination. Under standard conditions, the gener
Publikováno v:
Methods in Molecular Biology ISBN: 9781071621189
The reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) has proven to be a powerful system creating new opportunities to interrogate molecular mechanisms controlling cell fate determination. Under standard conditions, the gener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3656b333c40acd314ce569d45a79b92f
https://doi.org/10.1007/7651_2021_354
https://doi.org/10.1007/7651_2021_354
Autor:
Vera Garcia-Outeiral, Cristina Ameneiro, Adriana Escudero, Sonia Mulero-Navarro, Diana Guallar, Alejandro Fuentes-Iglesias, Tiago Moreira, Daniel Torrecilla, Alba Coego, Jose Maria Carvajal-Gonzalez, Miguel Fidalgo
Publikováno v:
Life Science Alliance
Although pluripotent cells lack circadian oscillations, this study reveals a novel function of the master circadian regulator BMAL1 in metabolism and early differentiation of embryonic stem cells.
BMAL1 is essential for the regulation of circadi
BMAL1 is essential for the regulation of circadi