Precision-guided treatment in high-risk pediatric cancers.

Autor: Lau LMS; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, New South Wales, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, New South Wales, Australia.; Kids Cancer Centre, Sydney Children's Hospital, Sydney, New South Wales, Australia., Khuong-Quang DA; Children's Cancer Centre, Royal Children's Hospital, Melbourne, Victoria, Australia.; Department of Paediatrics, Murdoch Children's Research Institute, University of Melbourne, Melbourne, Victoria, Australia., Mayoh C; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, New South Wales, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, New South Wales, Australia., Wong M; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, New South Wales, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, New South Wales, Australia., Barahona P; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, New South Wales, Australia., Ajuyah P; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, New South Wales, Australia., Senapati A; Kids Cancer Centre, Sydney Children's Hospital, Sydney, New South Wales, Australia., Nagabushan S; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, New South Wales, Australia.; Kids Cancer Centre, Sydney Children's Hospital, Sydney, New South Wales, Australia., Sherstyuk A; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, New South Wales, Australia., Altekoester AK; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, New South Wales, Australia., Fuentes-Bolanos NA; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, New South Wales, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, New South Wales, Australia.; Kids Cancer Centre, Sydney Children's Hospital, Sydney, New South Wales, Australia., Yeung V; Kids Cancer Centre, Sydney Children's Hospital, Sydney, New South Wales, Australia., Sullivan A; Oncology Services Group, Children's Health Queensland Hospital & Health Service, Brisbane, Queensland, Australia., Omer N; Oncology Services Group, Children's Health Queensland Hospital & Health Service, Brisbane, Queensland, Australia.; Frazer Institute, Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia., Diamond Y; Children's Cancer Centre, Royal Children's Hospital, Melbourne, Victoria, Australia., Jessop S; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, New South Wales, Australia.; Michael Rice Centre for Haematology and Oncology, Women's and Children's Hospital, Adelaide, South Australia, Australia., Battaglia L; Children's Cancer Centre, Monash Children's Hospital, Melbourne, Victoria, Australia., Zhukova N; Children's Cancer Centre, Monash Children's Hospital, Melbourne, Victoria, Australia.; Centre for Cancer Research, Hudson Institute of Medical Research, Melbourne, Victoria, Australia.; Department of Paediatrics, School of Clinical Sciences at Monash Health, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Victoria, Australia., Cui L; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, New South Wales, Australia., Lin A; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, New South Wales, Australia., Gifford AJ; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, New South Wales, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, New South Wales, Australia.; Anatomical Pathology, NSW Health Pathology, Prince of Wales Hospital, Sydney, New South Wales, Australia., Fleuren EDG; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, New South Wales, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, New South Wales, Australia., Dalla-Pozza L; Cancer Centre for Children, The Children's Hospital at Westmead, Sydney, New South Wales, Australia., Moore AS; Oncology Services Group, Children's Health Queensland Hospital & Health Service, Brisbane, Queensland, Australia., Khaw SL; Children's Cancer Centre, Royal Children's Hospital, Melbourne, Victoria, Australia.; Department of Paediatrics, Murdoch Children's Research Institute, University of Melbourne, Melbourne, Victoria, Australia., Eisenstat DD; Children's Cancer Centre, Royal Children's Hospital, Melbourne, Victoria, Australia.; Department of Paediatrics, Murdoch Children's Research Institute, University of Melbourne, Melbourne, Victoria, Australia., Gottardo NG; Department of Paediatric and Adolescent Oncology and Haematology, Perth Children's Hospital, Perth, Western Australia, Australia.; Telethon Kids Cancer Centre, Telethon Kids Institute, University of Western Australia, Perth, Western Australia, Australia., Wood PJ; Children's Cancer Centre, Monash Children's Hospital, Melbourne, Victoria, Australia.; Centre for Cancer Research, Hudson Institute of Medical Research, Melbourne, Victoria, Australia.; Department of Paediatrics, School of Clinical Sciences at Monash Health, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Victoria, Australia., Tapp H; Michael Rice Centre for Haematology and Oncology, Women's and Children's Hospital, Adelaide, South Australia, Australia., Alvaro F; Children's Cancer and Blood Disorders, John Hunter Children's Hospital, University of Newcastle, Newcastle, New South Wales, Australia., McCowage G; Cancer Centre for Children, The Children's Hospital at Westmead, Sydney, New South Wales, Australia., Nicholls W; Oncology Services Group, Children's Health Queensland Hospital & Health Service, Brisbane, Queensland, Australia.; Frazer Institute, Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia., Hansford JR; Children's Cancer Centre, Royal Children's Hospital, Melbourne, Victoria, Australia.; Department of Paediatrics, Murdoch Children's Research Institute, University of Melbourne, Melbourne, Victoria, Australia.; Michael Rice Centre for Haematology and Oncology, Women's and Children's Hospital, Adelaide, South Australia, Australia.; Department of Paediatrics, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Victoria, Australia.; South Australia Health and Medical Research Institute, Adelaide, South Australia, Australia.; South Australian immunoGENomics Cancer Institute, University of Adelaide, Adelaide, South Australia, Australia., Manoharan N; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, New South Wales, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, New South Wales, Australia.; Kids Cancer Centre, Sydney Children's Hospital, Sydney, New South Wales, Australia., Kotecha RS; Department of Paediatric and Adolescent Oncology and Haematology, Perth Children's Hospital, Perth, Western Australia, Australia.; Telethon Kids Cancer Centre, Telethon Kids Institute, University of Western Australia, Perth, Western Australia, Australia.; Curtin Medical School, Curtin University, Perth, Western Australia, Australia., Mateos MK; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, New South Wales, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, New South Wales, Australia.; Kids Cancer Centre, Sydney Children's Hospital, Sydney, New South Wales, Australia., Lock RB; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, New South Wales, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, New South Wales, Australia.; UNSW Centre for Childhood Cancer Research, UNSW Sydney, Sydney, New South Wales, Australia., Tyrrell V; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, New South Wales, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, New South Wales, Australia., Haber M; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, New South Wales, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, New South Wales, Australia., Trahair TN; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, New South Wales, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, New South Wales, Australia.; Kids Cancer Centre, Sydney Children's Hospital, Sydney, New South Wales, Australia., Cowley MJ; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, New South Wales, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, New South Wales, Australia., Ekert PG; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, New South Wales, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, New South Wales, Australia.; Department of Paediatrics, Murdoch Children's Research Institute, University of Melbourne, Melbourne, Victoria, Australia.; Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Marshall GM; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, New South Wales, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, New South Wales, Australia.; Kids Cancer Centre, Sydney Children's Hospital, Sydney, New South Wales, Australia., Ziegler DS; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, New South Wales, Australia. d.ziegler@unsw.edu.au.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, New South Wales, Australia. d.ziegler@unsw.edu.au.; Kids Cancer Centre, Sydney Children's Hospital, Sydney, New South Wales, Australia. d.ziegler@unsw.edu.au.

Publikováno v: Nature medicine [Nat Med] 2024 Jul; Vol. 30 (7), pp. 1913-1922. Date of Electronic Publication: 2024 Jun 06.

Protocol for a comprehensive prospective cohort study of trio-based whole-genome sequencing for underlying cancer predisposition in paediatric and adolescent patients newly diagnosed with cancer: the PREDICT study.

Autor: Fuentes Bolanos NA; Kids Cancer Centre, Sydney Children's Hospitals Network Randwick, Randwick, New South Wales, Australia.; Children's Cancer Institute, Lowy Cancer Centre, UNSW, Randwick, New South Wales, Australia., Padhye B; Cancer Centre for Children, The Children's Hospital at Westmead, Westmead, New South Wales, Australia bhavna.padhye@health.nsw.gov.au.; Kids Research, Children's Cancer Research Unit, The Children's Hospital at Westmead, Westmead, New South Wales, Australia., Daley M; Children's Cancer Institute, Lowy Cancer Centre, UNSW, Randwick, New South Wales, Australia., Hunter J; Behavioural Sciences Unit, Kids Cancer Centre, Randwick, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales, Sydney, New South Wales, Australia., Hetherington K; School of Women's and Children's Health, University of New South Wales, Sydney, New South Wales, Australia.; Behavioural Sciences Unit, Sydney Children's Hospital Randwick, Randwick, New South Wales, Australia., Warby M; Children's Cancer Institute, Lowy Cancer Centre, UNSW, Randwick, New South Wales, Australia.; Hereditary Cancer Centre, Prince of Wales Hospital Nelune Comprehensive Cancer Centre - NCCC, Randwick, New South Wales, Australia., Courtney E; Kids Cancer Centre, Sydney Children's Hospitals Network Randwick, Randwick, New South Wales, Australia.; Children's Cancer Institute, Lowy Cancer Centre, UNSW, Randwick, New South Wales, Australia., Kirk J; Familial Cancer Service, Westmead Hospital, Westmead, New South Wales, Australia.; Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia., Josephi-Taylor S; Department of Clinical Genetics, The Children's Hospital at Westmead, Westmead, New South Wales, Australia.; Discipline of Genomic Medicine, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia., Chen Y; Kids Research, Children's Cancer Research Unit, The Children's Hospital at Westmead, Westmead, New South Wales, Australia., Alvaro F; Paediatric Oncology Service, John Hunter Children's Hospital, Hunter Region Mail Centre, New South Wales, Australia., Barlow-Stewart K; Children's Cancer Institute, Lowy Cancer Centre, UNSW, Randwick, New South Wales, Australia.; Behavioural Sciences Unit, Kids Cancer Centre, Randwick, New South Wales, Australia., Wong-Erasmus M; Children's Cancer Institute, Lowy Cancer Centre, UNSW, Randwick, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales, Sydney, New South Wales, Australia., Barahona P; Children's Cancer Institute, Lowy Cancer Centre, UNSW, Randwick, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales, Sydney, New South Wales, Australia., Ajuyah P; Children's Cancer Institute, Lowy Cancer Centre, UNSW, Randwick, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales, Sydney, New South Wales, Australia., Altekoester AK; Children's Cancer Institute, Lowy Cancer Centre, UNSW, Randwick, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales, Sydney, New South Wales, Australia., Tyrrell VJ; Children's Cancer Institute, Lowy Cancer Centre, UNSW, Randwick, New South Wales, Australia., Lau LMS; Kids Cancer Centre, Sydney Children's Hospitals Network Randwick, Randwick, New South Wales, Australia.; Children's Cancer Institute, Lowy Cancer Centre, UNSW, Randwick, New South Wales, Australia., Wakefield C; Behavioural Sciences Unit, Kids Cancer Centre, Randwick, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales, Sydney, New South Wales, Australia., Sylvester D; Kids Research, Children's Cancer Research Unit, The Children's Hospital at Westmead, Westmead, New South Wales, Australia., Tucker K; Kids Cancer Centre, Sydney Children's Hospitals Network Randwick, Randwick, New South Wales, Australia.; Hereditary Cancer Centre, Prince of Wales Hospital Nelune Comprehensive Cancer Centre - NCCC, Randwick, New South Wales, Australia., Pinese M; Children's Cancer Institute, Lowy Cancer Centre, UNSW, Randwick, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales, Sydney, New South Wales, Australia., Dalla Pozza L; Cancer Centre for Children, The Children's Hospital at Westmead, Westmead, New South Wales, Australia., O'Brien TA; Kids Cancer Centre, Sydney Children's Hospitals Network Randwick, Randwick, New South Wales, Australia.

Publikováno v: BMJ open [BMJ Open] 2023 May 30; Vol. 13 (5), pp. e070082. Date of Electronic Publication: 2023 May 30.