Efr3b is essential for social recognition by modulating the excitability of CA2 pyramidal neurons.

Autor: Xiaojie Wei, Jing Wang, Enlu Yang, Yiping Zhang, Qi Qian, Xuekun Li, Fude Huang, Binggui Sun

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America; 1/16/2024, Vol. 121 Issue 3, p1-10, 36p

Hyccin/FAM126A deficiency reduces glial enrichment and axonal sheath, which are rescued by overexpression of a plasma membrane-targeting PI4KIIIα in Drosophila

Autor: Qichao Zhang, Baozhu Zhang, Nastasia.K.H. Lim, Xiao Zhang, Shiquan Meng, Jens R. Nyengaard, Fude Huang, Wen-An Wang

Publikováno v: Zhang, Q, Zhang, B, Lim, N K H, Zhang, X, Meng, S, Nyengaard, J R, Huang, F & Wang, W A 2022, ' Hyccin/FAM126A deficiency reduces glial enrichment and axonal sheath, which are rescued by overexpression of a plasma membrane-targeting PI4KIIIα in Drosophila ', Biochemical and Biophysical Research Communications, vol. 589, pp. 71-77 . https://doi.org/10.1016/j.bbrc.2021.11.106

Hyccin/FAM126A mutations are linked to hypomyelination and congenital cataract disease (HCC), but whether and how Hyccin/FAM126A deficiency causes hypomyelination remains undetermined. This study shows Hyccin/FAM126A expression was necessary for the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef8231b7737fa2d46a0c9bb19c28251a
https://pure.au.dk/portal/da/publications/hyccinfam126a-deficiency-reduces-glial-enrichment-and-axonal-sheath-which-are-rescued-by-overexpression-of-a-plasma-membranetargeting-pi4kiii-in-drosophila(438e2aab-6144-4607-be82-a6f3a6062b49).html

Brain-specific ablation of Efr3a promotes adult hippocampal neurogenesis

Autor: Qi, Qian, Qiuji, Liu, Dongming, Zhou, Hongyu, Pan, Zhiwei, Liu, Fangping, He, Suying, Ji, Dongpi, Wang, Wangxiao, Bao, Xinyi, Liu, Zhaoling, Liu, Heng, Zhang, Xiaoqin, Zhang, Ling, Zhang, Mingkai, Wang, Ying, Xu, Fude, Huang, Benyan, Luo, Binggui, Sun

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 31(5)

Efr3 is a newly identified plasma membrane protein and plays an important role in the phosphoinositide metabolism on the plasma membrane. However, although it is highly expressed in the brain, the functional significance of Efr3 in the brain is not c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::96467bb9733d0582aac182ed7f5195c6
https://pubmed.ncbi.nlm.nih.gov/28193719

Brain-specific ablation of Efr3a promotes adult hippocampal neurogenesis via the brain-derived neurotrophic factor pathway.

Autor: Qi Qian, Qiuji Liu, Dongming Zhou, Hongyu Pan, Zhiwei Liu, Fangping He, Suying Ji, Dongpi Wang, Wangxiao Bao, Xinyi Liu, Zhaoling Liu, Heng Zhang, Xiaoqin Zhang, Ling Zhang, Mingkai Wang, Ying Xu, Fude Huang, Benyan Luo, Binggui Sun

Publikováno v: FASEB Journal; May2017, Vol. 31 Issue 5, p2104-2113, 10p

SH2B1 is Involved in the Accumulation of Amyloid-β42 in Alzheimer's Disease.

Autor: Yijun Shen, Yiling Xia, Shiquan Meng, Nastasia K.H. Lim, Wenan Wang, Fude Huang

Publikováno v: Journal of Alzheimer's Disease; 2017, Vol. 55 Issue 2, p835-847, 13p