Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Fudan Miao"'
Autor:
Erika N. Scott, Galen E. B. Wright, Britt I. Drögemöller, Jafar S. Hasbullah, Erandika P. Gunaretnam, Fudan Miao, Amit P. Bhavsar, Fei Shen, Bryan P. Schneider, Bruce C. Carleton, Colin J. D. Ross
Publikováno v:
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-10 (2021)
Abstract Anthracyclines are highly effective chemotherapeutic agents; however, their clinical utility is limited by severe anthracycline-induced cardiotoxicity (ACT). Genome-wide association studies (GWAS) have uncovered several genetic variants asso
Externí odkaz:
https://doaj.org/article/ef67d46dd6034a2687778555b536d940
Autor:
Britt I. Drögemöller, Galen E.B. Wright, Jessica Trueman, Kaitlyn Shaw, Michelle Staub, Shahnaz Chaudhry, Fudan Miao, Michelle Higginson, Gabriella S.S. Groeneweg, James Brown, Laura A. Magee, Simon D. Whyte, Nicholas West, Sonia M. Brodie, Geert ’t Jong, Sara Israels, Howard Berger, Shinya Ito, Shahrad R. Rassekh, Shubhayan Sanatani, Colin J.D. Ross, Bruce C. Carleton
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 148, Iss , Pp 112684- (2022)
Background: Ondansetron is a highly effective antiemetic for the treatment of nausea and vomiting. However, this medication has also been associated with QT prolongation. Pharmacogenomic information on therapeutic response to ondansetron exists, but
Externí odkaz:
https://doaj.org/article/c4294f7b02a8413280155b30a5305cc8
Autor:
Jafar S Hasbullah, Erika N Scott, Amit P Bhavsar, Erandika P Gunaretnam, Fudan Miao, Hesham Soliman, Bruce C Carleton, Colin J D Ross
Publikováno v:
PLoS ONE, Vol 17, Iss 11, p e0276541 (2022)
The effectiveness of anthracycline chemotherapeutics (e.g., doxorubicin) is limited by anthracycline-induced cardiotoxicity (ACT). A nonsynonymous variant (S427L) in the retinoic acid receptor-γ (RARG) gene has been associated with ACT. This variant
Externí odkaz:
https://doaj.org/article/aab2c73896e040bcaf32a205127ff72f
Autor:
Braydon L. Burgess, Sean A. McIsaac, Kathryn E. Naus, Jeniffer Y. Chan, Gavin H.K. Tansley, Jing Yang, Fudan Miao, Colin J.D. Ross, Miranda van Eck, Michael R. Hayden, William van Nostrand, Peter St. George-Hyslop, David Westaway, Cheryl L. Wellington
Publikováno v:
Neurobiology of Disease, Vol 24, Iss 1, Pp 114-127 (2006)
Dietary or pharmacological manipulation of plasma lipids markedly influences amyloid deposition in animal models of Alzheimer’s Disease (AD). However, it is not known whether baseline plasma lipids in AD models differ from wild-type littermates thr
Externí odkaz:
https://doaj.org/article/4ad336a58d3b4986907f61b50a42f26c
Autor:
Susanne M. Clee, Nagat Bissada, Fudan Miao, Li Miao, A. David Marais, Howard E. Henderson, Pieternel Steures, Janet McManus, Bruce McManus, Renee C. LeBoeuf, John J.P. Kastelein, Michael R. Hayden
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 4, Pp 521-531 (2000)
Lipoprotein lipase (LPL) is a key enzyme in lipoprotein metabolism, and has been hypothesized to exert either pro- or anti-atherogenic effects, depending on its localization. Decreased plasma LPL activity is associated with the high triglyceride (TG)
Externí odkaz:
https://doaj.org/article/a365ed31b6cf4f43864defa640172edd
Autor:
Jafar S. Hasbullah, Amit P. Bhavsar, Britt I. Drögemöller, Fei Shen, Bruce Carleton, Erika N. Scott, Erandika P. Gunaretnam, Fudan Miao, Galen E.B. Wright, Colin J. D. Ross, Bryan P. Schneider
Publikováno v:
NPJ Genomic Medicine
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-10 (2021)
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-10 (2021)
Anthracyclines are highly effective chemotherapeutic agents; however, their clinical utility is limited by severe anthracycline-induced cardiotoxicity (ACT). Genome-wide association studies (GWAS) have uncovered several genetic variants associated wi
Autor:
Simon W. Rabkin, Fudan Miao, Jiri Frohlich, David Cassiman, Jennifer A. Collins, Singh N. Sadananda, Michael R. Hayden, Clara D.M. van Karnebeek, Liam R. Brunham, Bryan Sayson, Martin H. Kang, Sylvia Stockler, Lin-Hua Zhang
Publikováno v:
JIMD Reports ISBN: 9783662448625
Tangier disease is a rare, autosomal recessive disorder caused by mutations in the ABCA1 gene and is characterized by near absence of plasma high-density lipoprotein cholesterol, accumulation of cholesterol in multiple tissues, peripheral neuropathy,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5065aaff5c7c7e04339ef7a34f33876f
https://doi.org/10.1007/8904_2014_348
https://doi.org/10.1007/8904_2014_348
Autor:
Janet E. Wilson McManus, Nagat Bissada, Susanne M. Clee, John J.P. Kastelein, Michael R. Hayden, Howard E. Henderson, A. David Marais, Pieternel Steures, Li Miao, Renee C. LeBoeuf, Fudan Miao, Bruce M. McManus
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 4, Pp 521-531 (2000)
Lipoprotein lipase (LPL) is a key enzyme in lipoprotein metabolism, and has been hypothesized to exert either pro- or anti-atherogenic effects, depending on its localization. Decreased plasma LPL activity is associated with the high triglyceride (TG)
Autor:
Liam R. Brunham, G.K. Hovingh, P. J. Lansberg, Michael R. Hayden, Johan Wouter Jukema, Cedric J. Carter, Lin-Hua Zhang, Anton F. H. Stalenhoef, Colin J. D. Ross, Henk Visscher, John J. P. Kastelein, Bruce Carleton, Fudan Miao
Publikováno v:
Pharmacogenomics Journal, 12, 233-7
pharmacogenomics journal, 12(3), 233-237. Nature Publishing Group
Pharmacogenomics Journal, 12, 3, pp. 233-7
pharmacogenomics journal, 12(3), 233-237. Nature Publishing Group
Pharmacogenomics Journal, 12, 3, pp. 233-7
Statins reduce cardiovascular morbidity and mortality in appropriately selected patients. However, statin-associated myopathy is a significant risk associated with these agents. Recently, variation in the SLCO1B1 gene was reported to predict simvasta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03ecfb0e7536ceb5462623a21ceb7bcb
https://hdl.handle.net/1887/99007
https://hdl.handle.net/1887/99007
Autor:
Kathryn E. Naus, William E. Van Nostrand, Fudan Miao, Colin J. D. Ross, Peter St George-Hyslop, Jeniffer Chan, Gavin Tansley, Sean A. McIsaac, David Westaway, Jing Yang, Miranda Van Eck, Michael R. Hayden, Cheryl L. Wellington, Braydon L. Burgess
Publikováno v:
Neurobiology of Disease, Vol 24, Iss 1, Pp 114-127 (2006)
Dietary or pharmacological manipulation of plasma lipids markedly influences amyloid deposition in animal models of Alzheimer's Disease (AD). However, it is not known whether baseline plasma lipids in AD models differ from wild-type littermates throu