Zobrazeno 1 - 10
of 700
pro vyhledávání: '"Fuchu He"'
Autor:
Qilin Zhang, Ziyan Xu, Rui Han, Yunzhi Wang, Zhen Ye, Jiajun Zhu, Yixin Cai, Fan Zhang, Jiangyan Zhao, Boyuan Yao, Zhaoyu Qin, Nidan Qiao, Ruofan Huang, Jinwen Feng, Yongfei Wang, Wenting Rui, Fuchu He, Yao Zhao, Chen Ding
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-32 (2024)
Abstract Skull-base chordoma is a rare, aggressive bone cancer with a high recurrence rate. Despite advances in genomic studies, its molecular characteristics and effective therapies remain unknown. Here, we conduct integrative genomics, transcriptom
Externí odkaz:
https://doaj.org/article/7058055cd26443cc90edde525ed079e9
Autor:
Yushan Hou, Siqi Wang, Yiming Zhang, Xiaofen Huang, Xiuyuan Zhang, Fuchu He, Chunyan Tian, Aihua Sun
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 5, Pp 4004-4020 (2024)
Alternative splicing has been shown to participate in tumor progression, including hepatocellular carcinoma. The poor prognosis of patients with HCC calls for molecular classification and biomarker identification to facilitate precision medicine. We
Externí odkaz:
https://doaj.org/article/ebfd8a674e9f468480b9e7f0d5982f64
Autor:
Yi Liu, Yun Yang, Wendong Chen, Feng Shen, Linhai Xie, Yingying Zhang, Yuanjun Zhai, Fuchu He, Yunping Zhu, Cheng Chang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Retention time (RT) alignment is a crucial step in liquid chromatography-mass spectrometry (LC-MS)-based proteomic and metabolomic experiments, especially for large cohort studies. The most popular alignment tools are based on warping functi
Externí odkaz:
https://doaj.org/article/2783aa1f69e34985b4922d8751fda521
Autor:
Jiangyan Zhao, Chenxing Ji, Haixia Cheng, Zhen Ye, Boyuan Yao, Ming Shen, Xuefei Shou, Xiang Zhou, Hongying Ye, Zhaoyun Zhang, Hong Chen, Yongfei Wang, Fuchu He, Yao Zhao, Wei Gong, Qilin Zhang, Nidan Qiao
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 9, Iss 6, Pp 488-497 (2023)
Abstract Studies describing the clinical presentation and prognosis of patients with silent PIT1 (pituitary specific transcription factor)‐lineage pituitary neuroendocrine tumors (PitNETs) are rare. We identified patients with positive PIT1 tumor s
Externí odkaz:
https://doaj.org/article/4e9e7b4304b84c23a891cd39b82e0c6b
Autor:
Sha Tian, Dongdong Zhan, Ying Yu, Yunzhi Wang, Mingwei Liu, Subei Tan, Yan Li, Lei Song, Zhaoyu Qin, Xianju Li, Yang Liu, Yao Li, Shuhui Ji, Shanshan Wang, Proteomic Massive Analysis and Quality Control Consortium, Yuanting Zheng, Fuchu He, Jun Qin, Chen Ding
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-31 (2023)
Abstract Background Quantitative proteomics is an indispensable tool in life science research. However, there is a lack of reference materials for evaluating the reproducibility of label-free liquid chromatography-tandem mass spectrometry (LC–MS/MS
Externí odkaz:
https://doaj.org/article/d359ba8b1e6743b780ec31a33c157f8a
Autor:
Wenhao Shi, Yushen Wang, Chen Xu, Yan Li, Sai Ge, Bin Bai, Kecheng Zhang, Yunzhi Wang, Nairen Zheng, Juan Wang, Shiqi Wang, Gang Ji, Jipeng Li, Yongzhan Nie, Wenquan Liang, Xiaosong Wu, Jianxin Cui, Yi Wang, Lin Chen, Qingchuan Zhao, Lin Shen, Fuchu He, Jun Qin, Chen Ding
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
The molecular differences between the two major gastric cancer subtypes diffuse-type gastric cancer (DGC) and intestinaltype gastric cancer (IGC) remain to be investigated. Here, integrated analysis of proteome, phospho-proteome and transcription fac
Externí odkaz:
https://doaj.org/article/b8d7e9eefad24deeb27fe648beb9743f
Autor:
Jingbo Qie, Yang Liu, Yunzhi Wang, Fan Zhang, Zhaoyu Qin, Sha Tian, Mingwei Liu, Kai Li, Wenhao Shi, Lei Song, Mingjun Sun, Yexin Tong, Ping Hu, Tao Gong, Xiaqiong Wang, Yi Huang, Bolong Lin, Xuesen Zheng, Rongbin Zhou, Jie Lv, Changsheng Du, Yi Wang, Jun Qin, Wenjun Yang, Fuchu He, Chen Ding
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-23 (2022)
Macrophage is located in different tissue to serve diverse functions. Here the authors use mass spectrometry and bulk RNA-sequencing to profile 11 mouse macrophage populations from 8 tissues, and combine their de novo data with public datasets to rep
Externí odkaz:
https://doaj.org/article/42aa5c3f294d4fc78c544a437d316019
Autor:
Yexin Tong, Mingjun Sun, Lingli Chen, Yunzhi Wang, Yan Li, Lingling Li, Xuan Zhang, Yumeng Cai, Jingbo Qie, Yanrui Pang, Ziyan Xu, Jiangyan Zhao, Xiaolei Zhang, Yang Liu, Sha Tian, Zhaoyu Qin, Jinwen Feng, Fan Zhang, Jiajun Zhu, Yifan Xu, Wenhui Lou, Yuan Ji, Jianyuan Zhao, Fuchu He, Yingyong Hou, Chen Ding
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-47 (2022)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease with poor prognosis. Proteogenomic characterization and integrative proteomic analysis provide a functional context to annotate genomic abnormalities with prognostic
Externí odkaz:
https://doaj.org/article/3aedf2d3f1e44ba79edc3fe33867e9b0
Autor:
Limin Shang, Yuehui Zhang, Yuchen Liu, Chaozhi Jin, Yanzhi Yuan, Chunyan Tian, Ming Ni, Xiaochen Bo, Li Zhang, Dong Li, Fuchu He, Jian Wang
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 20, Iss 4, Pp 795-807 (2022)
Genome-wide physical protein–protein interaction (PPI) mapping remains a major challenge for current technologies. Here, we reported a high-efficiency BiFC-seq method, yeast-enhanced green fluorescent protein-based bimolecular fluorescence compleme
Externí odkaz:
https://doaj.org/article/e432f4cc46104e6b92fbee44a981d6dc
Autor:
Zhongyang Liu, Honglei Li, Zhaoyu Jin, Yang Li, Feifei Guo, Yangzhige He, Xinyue Liu, Yaning Qi, Liying Yuan, Fuchu He, Dong Li
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 20, Iss 4, Pp 780-794 (2022)
After decades of development, protein and peptide drugs have now grown into a major drug class in the marketplace. Target identification and validation are crucial for the discovery of protein and peptide drugs, and bioinformatics prediction of targe
Externí odkaz:
https://doaj.org/article/eac9ef0bccac4de894acbc5253de0b32