Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Fuat Doymaz"'
Publikováno v:
Principles and Practices of Lyophilization in Product Development and Manufacturing ISBN: 9783031126338
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b17c3c030a660cd6eafb2bb6de9e27b
https://doi.org/10.1007/978-3-031-12634-5_28
https://doi.org/10.1007/978-3-031-12634-5_28
Publikováno v:
Quality by Design for Biopharmaceutical Drug Product Development ISBN: 9781493923151
This chapter provides a guideline for assessing the ability to manufacture homogeneous drug product batches during validation of commercial drug product manufacturing processes that span formulation, fill, and finish steps. A stepwise approach that s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd2d4ec26037adfc2d1f3ea4e5249354
https://doi.org/10.1007/978-1-4939-2316-8_26
https://doi.org/10.1007/978-1-4939-2316-8_26
Autor:
Fuat Doymaz
Publikováno v:
Quality by Design for Biopharmaceutical Drug Product Development ISBN: 9781493923151
This chapter illustrates the concept of multivariate statistical process monitoring (MSPM) with data from a biopharmaceutical drug product lyophilization process. It provides the practitioner with steps needed for pretreatment of the data, modeling,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79360e84ad62c0dff3807ac814235bd8
https://doi.org/10.1007/978-1-4939-2316-8_24
https://doi.org/10.1007/978-1-4939-2316-8_24
Publikováno v:
Industrial & Engineering Chemistry Research. 42:5836-5849
A multivariate statistical regression technique is proposed to address underlying nonlinear correlations among the predictor variables, as well as between the predictor variables and the response variable. The method is based on a neural network arch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e4d75c4a9cad871f107b7dffb99db1e
https://doi.org/10.1021/ie0109051
https://doi.org/10.1021/ie0109051
Publikováno v:
Computers & Chemical Engineering. 25:1549-1559
A robust filtering methodology is proposed that reliably preserves the information encapsulated in a process signal corrupted with noise and outliers. The method is proven to be effective on benchmark examples and implemented successfully in real-tim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6c6b97c92e7d154b7c57febae2fcb43
https://doi.org/10.1016/s0098-1354(01)00718-9
https://doi.org/10.1016/s0098-1354(01)00718-9
Publikováno v:
Journal of Process Control. 11:343-359
An operator support system (OSS) is proposed to reliably retain salient information in a high dimensional and correlated database, to uncover linear and nonlinear correlations among variables, to reconstruct failed/unavailable sensors, and to assess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9569b20d2cfd0028387d6284c8430076
https://doi.org/10.1016/s0959-1524(00)00004-4
https://doi.org/10.1016/s0959-1524(00)00004-4
Publikováno v:
Chemometrics and Intelligent Laboratory Systems. 55:109-123
A novel approach is proposed to isolate sensors that are affected by the root cause of nonconforming operation and to distinguish between failed sensors and process upsets. Systems having multivariate nature can be monitored by building a principal c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c259293d0a9e31bef6dee5337041803a
https://doi.org/10.1016/s0169-7439(00)00126-x
https://doi.org/10.1016/s0169-7439(00)00126-x
Publikováno v:
IFAC Proceedings Volumes. 33:39-44
A novel approach is proposed to isolate the sensors that are affected by the root cause of non-conforming operation and to distinguish between the failed sensors and process upsets. Systems having multivariate nature can be monitored by building a pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b934ddbda6bec772d9ad28bd6ce34201
https://doi.org/10.1016/s1474-6670(17)38515-4
https://doi.org/10.1016/s1474-6670(17)38515-4
Autor:
Jozsef Lango, Jie Jing, Isaac N. Pessah, Bruce D. Hammock, Lili Chen, Bora Inceoglu, Fuat Doymaz
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 100(3)
Scorpion venom is a complex mixture of salts, small molecules, peptides, and proteins. Scorpions employ this valuable tool in several sophisticated ways for subduing prey, deterring predators, and possibly during mating. Here, a subtle but clever str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::851e7375856620b2cf27ce03ade89624
https://pubmed.ncbi.nlm.nih.gov/12552107
https://pubmed.ncbi.nlm.nih.gov/12552107