Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Fuad Gahnem"'
Specific prorenin/renin binding (ProBP) Identification and characterization of a novel membrane site
Autor:
Jean E. Sealey, Lufei Hu, Tina Pitarresi, Fuad Gahnem, Daniel F. Catanzaro, Thomas N. Lavin, John H. Laragh
Publikováno v:
American Journal of Hypertension. 9:491-495
Renin can be detected in cardiovascular and other tissues but it disappears after bilateral nephrectomy indicating that tissues can take up or bind renal renin from the circulation. If renin uptake is the result of specific binding, plasma prorenin m
Publikováno v:
American Journal of Hypertension. 7:899-904
Publikováno v:
American Journal of Hypertension. 5:495-501
Human renin can cleave rat angiotensinogen, yet infusion of human renin into rats causes only a modest increase in blood pressure. We therefore investigated whether there is a factor in rat plasma which inhibits human renin activity. The addition of
Autor:
Jean E. Sealey, M J Camargo, Gary D. James, Daniel F. Catanzaro, Wallace G. Campbell, Fuad Gahnem, John H. Laragh
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 27(5)
Abstract We measured plasma prorenin and renin levels, renal renin mRNA, renal anti-renin and anti–prorenin-prosequence immunoreactivity, and blood pressure in maturing Brookhaven Dahl salt-sensitive (Dahl S) and salt-resistant (Dahl R) rats during
Publikováno v:
Scopus-Elsevier
Prorenin can be converted to renin by limited proteolysis with trypsin. In the current study we compared conditions for activation of human renal and ovarian prorenin and cat renal prorenin with either liquid-phase trypsin or trypsin bound to sepharo
Autor:
N. Von Lutterotti, J.-M. Halimi, Jean E. Sealey, Fuad Gahnem, John H. Laragh, Speranza Rubattu, Wallace G. Campbell
Publikováno v:
Scopus-Elsevier
A greater renin system is proposed. Evidence is presented that a greater renin system exists that has both vasodilator and vasoconstrictor properties. Vasodilator activity is induced by prorenin, vasoconstrictor activity by renin. Our model is based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab0935ff85e7e9906d5e1d1b64f8e03e
http://hdl.handle.net/11573/423290
http://hdl.handle.net/11573/423290
Publikováno v:
American Journal of Hypertension. 10:14A
Publikováno v:
Journal of Hypertension. 13:27
Publikováno v:
Journal of Hypertension. 13:91
Objective : Data concerning the effect of angiotensin II (Ang II) on plasma angiotensinogen levels are conflicting. Although Ang II is reported to stimulate the biosynthesis of angiotensinogen, plasma angiotensinogen is often depleted by renin when t