Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Fu-Ning Hsu"'
Autor:
Xiao-Jun Xie, Fu-Ning Hsu, Xinsheng Gao, Wu Xu, Jian-Quan Ni, Yue Xing, Liying Huang, Hao-Ching Hsiao, Haiyan Zheng, Chenguang Wang, Yani Zheng, Alus M Xiaoli, Fajun Yang, Sarah E Bondos, Jun-Yuan Ji
Publikováno v:
PLoS Biology, Vol 13, Iss 7, p e1002207 (2015)
The steroid hormone ecdysone and its receptor (EcR) play critical roles in orchestrating developmental transitions in arthropods. However, the mechanism by which EcR integrates nutritional and developmental cues to correctly activate transcription re
Externí odkaz:
https://doaj.org/article/97aa8fbd824044d7bdd28701d7559ceb
Autor:
Tianyi Zhang, Yang Liao, Fu-Ning Hsu, Robin Zhang, Jennifer S Searle, Xun Pei, Xuan Li, Hyung Don Ryoo, Jun-Yuan Ji, Wei Du
Publikováno v:
PLoS Genetics, Vol 10, Iss 5, p e1004357 (2014)
Inactivation of the Rb tumor suppressor can lead to increased cell proliferation or cell death depending on specific cellular context. Therefore, identification of the interacting pathways that modulate the effect of Rb loss will provide novel insigh
Externí odkaz:
https://doaj.org/article/402f5da463074edd92b2497e837e5a38
Autor:
Fu-Ning Hsu, Xiao-Jun Xie, Xiao Li, Mengmeng Liu, Rajitha-Udakara-Sampath Hemba-Waduge, Jun-Yuan Ji, Xinsheng Gao, Wu Xu
Publikováno v:
Developmental Biology. 444:62-70
The complex interplay between genetic and environmental factors, such as diet and lifestyle, defines the initiation and progression of multifactorial diseases, including cancer, cardiovascular and metabolic diseases, and neurological disorders. Given
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0caf4b2f4842bfa4c8f5054b3119e515
https://doi.org/10.1016/j.ydbio.2018.10.001
https://doi.org/10.1016/j.ydbio.2018.10.001
Autor:
Fu-Ning Hsu
Publikováno v:
Adaptive Medicine. 10:34-42
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5c861fd6e4f83f2a870fd272d6c02a8
https://doi.org/10.4247/am.2018.abi198
https://doi.org/10.4247/am.2018.abi198
Autor:
Tsung-Ying Yang, Hsin Yi Wang, G. M. Shazzad Hossain Prince, Fu-Ning Hsu, Chih Ho Lai, Muhammet Oner, Ching Han Yu, Mei Chih Chen, Chieh-Lin Jerry Teng, Eugene Lin, Kun Yuan Chiu, Chia Herng Yue, Jer Tsong Hsieh, Ho Lin
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 16, p 3881 (2019)
International Journal of Molecular Sciences, Vol 20, Iss 16, p 3881 (2019)
Cyclin-dependent kinase 5 (CDK5) is a unique member of the cyclin-dependent kinase family. CDK5 is activated by binding with its regulatory proteins, mainly p35, and its activation is essential in the development of the central nervous system (CNS) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58901d58ba8a79a6c9a2a66b64c78da4
http://europepmc.org/articles/PMC6720211
http://europepmc.org/articles/PMC6720211
Autor:
Tianyi Zhang, Mengmeng Liu, Xiao-Jun Xie, Xun Pei, Fu-Ning Hsu, Xinsheng Gao, Wei Du, Jun-Yuan Ji, Xiao Li, Yang Liao
Publikováno v:
Proceedings of the National Academy of Sciences. 114
Deregulated Wnt signaling and altered lipid metabolism have been linked to obesity, diabetes, and various cancers, highlighting the importance of identifying inhibitors that can modulate Wnt signaling and aberrant lipid metabolism. We have establishe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::509ca2f7f45a3668375051e0e1c3538e
https://doi.org/10.1073/pnas.1621048114
https://doi.org/10.1073/pnas.1621048114
A developmental genetic analysis of the lysine demethylase KDM2 mutations in Drosophila melanogaster
Autor:
Wu Xu, Xinjie Ren, Xiao-Jun Xie, Fu-Ning Hsu, Jian-Quan Ni, Jun-Yuan Ji, Xinsheng Gao, Yani Zheng
Publikováno v:
Mechanisms of Development. 133:36-53
Post-translational modification of histones plays essential roles in the transcriptional regulation of genes in eukaryotes. Methylation on basic residues of histones is regulated by histone methyltransferases and histone demethylases, and misregulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a663767224d301890dee2d23679c33b
https://doi.org/10.1016/j.mod.2014.06.003
https://doi.org/10.1016/j.mod.2014.06.003
Autor:
Kuan Chia Lin, Pei Chi Li, Fu-Ning Hsu, Eugene Lin, Ho Lin, Mei Chih Chen, Jer Tsong Hsieh, Ming Ching Chiang, Yu Ting Peng
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 305:E975-E986
Cyclin-dependent kinase 5 (Cdk5) is known to regulate prostate cancer metastasis. Our previous results indicated that Cdk5 activates androgen receptor (AR) and supports prostate cancer growth. We also found that STAT3 is a target of Cdk5 in promoting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7faed69fc4c7bb50405d2eef8003506c
https://doi.org/10.1152/ajpendo.00615.2012
https://doi.org/10.1152/ajpendo.00615.2012
Autor:
Beihua Kong, Jun-Yuan Ji, Jie Zhou, Xiao-Jun Xie, Chenguang Wang, Sankar Addya, Fu-Ning Hsu, Tao Jiang, Weihua Li, Cunzhong Yuan, Yanhong Tai, Weiting Gu, Lifeng Tian
Publikováno v:
Cell Cycle. 12:987-999
CDK8 is either amplified or mutated in a variety of human cancers, and CDK8 functions as an oncoprotein in melanoma and colorectal cancers. Previously, we reported that loss or reduction of CDK8 results in aberrant fat accumulation in Drosophila and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e655ead421dbf594a6bb9853a90629c4
https://doi.org/10.4161/cc.24003
https://doi.org/10.4161/cc.24003
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 300:E902-E908
Androgen ablation therapy is the most common strategy for suppressing prostate cancer progression; however, tumor cells eventually escape androgen dependence and progress to an androgen-independent phase. The androgen receptor (AR) plays a pivotal ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a83874ad7185b61971aaeb96a44eced8
https://doi.org/10.1152/ajpendo.00610.2010
https://doi.org/10.1152/ajpendo.00610.2010