Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Fu-Ming Zhou"'
Publikováno v:
Neurobiology of Disease, Vol 181, Iss , Pp 106096- (2023)
Striatal medium spiny neurons (MSNs) and striatal dopamine (DA) innervation are profoundly important for brain function such as motor control and cognition. A widely accepted theory posits that striatal DA loss causes (or leads to) MSN dendritic atro
Externí odkaz:
https://doaj.org/article/27c63f48dede4474963f0bc2b546522e
Autor:
John I. Broussard, Kechun Yang, Amber T. Levine, Theodoros Tsetsenis, Daniel Jenson, Fei Cao, Isabella Garcia, Benjamin R. Arenkiel, Fu-Ming Zhou, Mariella De Biasi, John A. Dani
Publikováno v:
Cell Reports, Vol 14, Iss 8, Pp 1930-1939 (2016)
Dopamine release during reward-driven behaviors influences synaptic plasticity. However, dopamine innervation and release in the hippocampus and its role during aversive behaviors are controversial. Here, we show that in vivo hippocampal synaptic pla
Externí odkaz:
https://doaj.org/article/34ca68778ca14e4ca0897cfb9bf77e84
Publikováno v:
Frontiers in Neural Circuits, Vol 12 (2018)
Dopamine (DA) profoundly stimulates motor function as demonstrated by the hypokinetic motor symptoms in Parkinson's disease (PD) and by the hyperkinetic motor side effects during dopaminergic treatment of PD. Dopamine (DA) receptor-bypassing, optogen
Externí odkaz:
https://doaj.org/article/9adeb46c15884698b647aaab31877481
Autor:
Yuhan Wang, Fu-Ming Zhou
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Dopamine (DA) is required for motor function in vertebrate animals including humans. The striatum, a key motor control center, receives a dense DA innervation and express high levels of DA D1 receptors (D1Rs) and D2 receptors (D2Rs). Other brain area
Externí odkaz:
https://doaj.org/article/ab5551b57319413f8a3e4fdb5c560675
Publikováno v:
Frontiers in Aging Neuroscience, Vol 9 (2017)
Epidemiological studies indicate that physical activity and exercise may reduce the risk of developing Parkinson's disease (PD), and clinical observations suggest that physical exercise can reduce the motor symptoms in PD patients. In experimental an
Externí odkaz:
https://doaj.org/article/842f999152244412a123b643089dff5c
Autor:
Ling Chen, Rajendra Raghow, Xing-Lin Tan, Geng Lin, Fu-Ming Zhou, Xingyong Chen, Andy Y. Shih, Francesca-Fang Liao, Wei Zheng
Publikováno v:
The American Journal of Pathology. 191:1932-1945
Age-related cerebral small-vessel disease (CSVD) is a major cause of stroke and dementia. Despite a widespread acceptance of small-vessel arteriopathy, lacunar infarction, diffuse white matter injury, and cognitive impairment as four cardinal feature
Autor:
Xingyong Chen, Ling Chen, Geng Lin, Zhengjun Wang, Mahesh C. Kodali, Mingqi Li, Huimin Chen, Sarah G. Lebovitz, Tyler C. Ortyl, Lexiao Li, Saifudeen Ismael, Purnima Singh, Kafait U. Malik, Tauheed Ishrat, Fu-Ming Zhou, Wei Zheng, Francesca-Fang Liao
Publikováno v:
Molecular psychiatry. 27(11)
Vascular cognitive impairment and dementia (VCID) is the second most common form of dementia after Alzheimer’s disease (AD). Currently, the mechanistic insights into the evolution and progression of VCID remain elusive. White matter change represen
Autor:
Qian Wang, Fu-Ming Zhou
Publikováno v:
Neuropharmacology. 148:229-243
Adenosine A2a receptors (A2aRs) are highly and selectively expressed in D2-medium spiny neurons (D2-MSNs) that also express a high level of dopamine D2 receptors (D2Rs). However, it was not established how A2aR activity affects D2-MSN excitability, l
Autor:
Fu-Ming Zhou
Constituting over 90% of the striatal neuronal population, medium spiny neurons (MSNs) are the projection neurons of the striatum. A distinct feature of MSNs is their rich dendritic spines, in which cortical and thalamic glutamatergic synaptic inputs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::265350fea7953408538cef75faf7aacb
https://doi.org/10.1016/b978-0-12-815950-7.00025-4
https://doi.org/10.1016/b978-0-12-815950-7.00025-4