Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Fu-Lian Gong"'
Autor:
Lei Wang, Yu-jie Wang, Rong Wang, Fu-lian Gong, Yu-huan Shi, Sheng-nan Li, Pan-pan Chen, Yong-fang Yuan
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Background Recent research shows that tumor-associated macrophages (TAMs) are the primary consumers of glucose in tumor tissue, surpassing that of tumor cells. Our previous studies revealed that inhibiting glucose uptake impairs the survival
Externí odkaz:
https://doaj.org/article/3ee77fc037254e95ba7254caf62d6d68
Publikováno v:
Acta Pharmacol Sin
Large amounts of tumor-associated macrophages (TAM), which are predominately localized in hypoxia area of the tumor tissue, are associated with the malignant progression of the tumor. In the present study, we investigated the inhibitory effects of mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fdc3c111d6bc0ca00cc414452d66bae
https://doi.org/10.1038/s41401-021-00748-8
https://doi.org/10.1038/s41401-021-00748-8
Publikováno v:
JOURNAL OF CELLULAR BIOCHEMISTRY
Angiogenesis and vasculogenic mimicry (VM) are the main causes of tumor metastasis and recurrence. In this study, we investigated the antiangiogenesis and anti-VM formation of a novel microtubule depolymerizing agent, DHPAC, as well as combretastatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03538689fd5bb56a5dd3ad611bb87161
Autor:
Yan-Na Cheng, Xiao-Xia Yang, Yi-Fan Dang, Shao-Hui Yang, Fu-Lian Gong, Xiu-Li Guo, Xiao-Ning Jiang
Publikováno v:
Journal of drug targeting. 29(3)
Insulin resistance promotes the occurrence of liver cancer and decreases its chemosensitivity. Rosiglitazone (ROSI), a thiazolidinedione insulin sensitiser, could be used for diabetes with insulin resistance and has been reported to show anticancer e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88259117c64d0c15ccdb637a789c9767
https://pubmed.ncbi.nlm.nih.gov/33115283
https://pubmed.ncbi.nlm.nih.gov/33115283
Publikováno v:
Chemico-Biological Interactions. 296:162-170
Rosiglitazone (ROSI), a member of thiazolidinediones (TZDs) which act as high-affinity agonists of the nuclear receptor peroxisome-proliferator-activated receptor-γ (PPARγ), is clinically used as an antidiabetic drug which could attenuate the insul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fac6e2bdba5755e0e7833bdcd9fdbb6c
https://doi.org/10.1016/j.cbi.2018.09.019
https://doi.org/10.1016/j.cbi.2018.09.019
Autor:
Hui-Hui Zhang, Ying Zhang, Hong-Yuan Wang, Zhen-Ning Lu, Lu-Gang Yu, Yan-Na Cheng, Fu-Lian Gong, Xiu-Li Guo, Zhao-Peng Liu
Publikováno v:
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
Multidrug resistance (MDR) is one of major obstacles to effective chemotherapeutic treatment of cancer. This study showed that DHPAC, 2-(6-ethoxy-3-(3-ethoxyphenylamino) -1-methyl-1,4-dihydroindeno[1,2-c]pyrazol-7-yloxy) acetamide, a novel compound t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fda2d603c4df3ffef7d13b78b3dd1619
https://doi.org/10.1016/j.biocel.2017.10.012
https://doi.org/10.1016/j.biocel.2017.10.012
Publikováno v:
Chemico-biological interactions. 309
Galectin-3 (Gal-3), the only chimeric lectin of the galectin family, affects numerous biological processes and seems to be involved in different physiological and pathophysiological conditions, such as tumor development, invasion and metastasis as we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d44788a02fb3928180c30a8a4569ebb0
https://pubmed.ncbi.nlm.nih.gov/31228468
https://pubmed.ncbi.nlm.nih.gov/31228468
Autor:
Fu-Lian Gong, Xiu-Li Guo, Xiao-Xia Yang, Ying-Shuang Li, Lin Zhao, Lei Wang, Xinke Zhang, Lu-Gang Yu
Publikováno v:
Biochemical Pharmacology
Tumor-associated macrophages (TAMs) have been shown to be associated with poor prognosis of cancer and are predominately localized in the hypoxia regions of tumor. We demonstrated in this study that hypoxia increases the synthesis and secretion of ga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::381d18d70d88b459214dba90c01fe6a4
https://doi.org/10.1016/j.bcp.2020.114113
https://doi.org/10.1016/j.bcp.2020.114113
Publikováno v:
Molecular Carcinogenesis
Hepatocellular carcinoma (HCC) has poor prognosis due to the advanced disease stages by the time it is diagnosed, high recurrence rates and metastasis. In the present study, we investigated the effects of metformin (a safe anti-diabetic drug) and cur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28613d0aeb0a036090b63cf429e99667
https://pubmed.ncbi.nlm.nih.gov/28833603
https://pubmed.ncbi.nlm.nih.gov/28833603