Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Fu-Han Gong"'
Autor:
Fu-Han Gong, Wen-Lin Cheng, Haiping Wang, Maomao Gao, Juan-Juan Qin, Yan Zhang, Xia Li, Xueyong Zhu, Hao Xia, Zhi-Gang She
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 4, Pp 658-669 (2018)
Atherosclerosis is considered to be a chronic inflammatory disease that can lead to severe clinically important cardiovascular events. miR-150 is a small noncoding RNA that significantly enhances inflammatory responses by upregulating endothelial cel
Externí odkaz:
https://doaj.org/article/75be96c32883406c836a526776f56a72
Autor:
Xin Zhang, Jing Li, Juan-Juan Qin, Wen-Lin Cheng, Xueyong Zhu, Fu-Han Gong, Zhigang She, Zan Huang, Hao Xia, Hongliang Li
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 5, Pp 895-906 (2017)
Oncostatin M (OSM) is a secreted cytokine mainly involved in chronic inflammatory and cardiovascular diseases through binding to OSM receptor β (OSMR-β). Recent studies demonstrated that the presence of OSM contributed to the destabilization of ath
Externí odkaz:
https://doaj.org/article/eb71a045aa0943ff879d153f7e18305e
Autor:
Hong Zhi, Fu‐Han Gong, Wen‐Lin Cheng, Kongbo Zhu, Long Chen, Yuyu Yao, Xingzhou Ye, Xue‐Yong Zhu, Hongliang Li
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 12 (2018)
Background Tollip, a well‐established endogenous modulator of Toll‐like receptor signaling, is involved in cardiovascular diseases. The aim of this study was to investigate the role of Tollip in neointima formation and its associated mechanisms.
Externí odkaz:
https://doaj.org/article/38d8460d4e0940198a387eb69e58b828
Autor:
Wen‐Lin Cheng, Yang Yang, Xiao‐Jing Zhang, Junhong Guo, Jun Gong, Fu‐Han Gong, Zhi‐Gang She, Zan Huang, Hao Xia, Hongliang Li
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 2 (2017)
BackgroundDickkopf‐3 (DKK3) is a negative regulator of the Wnt/β‐catenin signaling pathway, which is involved in inflammation. However, little is known about the relationship between DKK3 expression and the progression of atherosclerosis. The ai
Externí odkaz:
https://doaj.org/article/4c86cd104ea24a818138ac8a310601ab
Autor:
Lan, Zhang, Qian-Wei, Huang, Yan-Fen, Pu, Xiao-Qiang, Xiao, Bian-Jing, Song, Xue-Ping, Zhang, Yong-Sheng, Yang, Yu-Song, Zhang, Fu-Han, Gong
Publikováno v:
American Journal of Hypertension. 35:454-461
Background RIP2 is an adaptor protein contributing to the activation of nuclear factor-κB induced by TNF receptor-associated factor (TRAF) and nucleotide oligomerization domain (NOD)-dependent signaling implicated in innate and adaptive immune respo
Autor:
Xi-Lu Chen, Sheng-Ping Chao, Yong-Sheng Yang, Quan Zhang, Xiao-Qiang Xiao, Wen-Lin Cheng, Bian-Jing Song, Fu-Han Gong
Publikováno v:
American Journal of Hypertension. 35:87-95
BACKGROUND MicroRNAs serve as important regulators of the pathogenesis of cardiac hypertrophy. Among them, miR-183 is well documented as a novel tumor suppressor in previous studies, whereas it exhibits a downregulated expression in cardiac hypertrop
Autor:
Fang Zhao, Wen-Lin Cheng, Xi-Lu Chen, Wen-Hao Song, Quan Zhang, Jian-Lei Cao, Ting Yang, Fu-Han Gong
Publikováno v:
Journal of Cardiovascular Pharmacology. 76:237-245
As a receptor for transforming growth factor-β, nodal and activin, activin receptor-like kinase 7 (ALK7) previously acts as a suppressor of tumorigenesis and metastasis, which has emerged to play a key role in cardiovascular diseases. However, the p
Autor:
Li Long, Yong-Sheng Yang, Zhen-lin Shu, Xue-ping Zhang, Xiao-Qiang Xiao, Sheng Huang, Fu-han Gong, Xue-sheng Wang
Publikováno v:
Open Medicine
Open Medicine, Vol 14, Iss 1, Pp 939-944 (2019)
Open Medicine, Vol 14, Iss 1, Pp 939-944 (2019)
Atherosclerosis and chemokines are strongly related, but the role of the chemokine CXCL17 in atherogenesis is still poorly understood. We aim to investigate the serum CXCL17 levels in different stages of patients with coronary heart disease and explo
Autor:
Xueyong Zhu, Yan Zhang, Wen-Lin Cheng, Cheng Zhang, Jingjing Tong, Lihua Zhu, Hao Xia, Juan-Juan Qin, Fu-Han Gong, Zhi-Gang She, Hai-Ping Wang
Publikováno v:
Clinical Science. 132:1199-1213
Background - Mindin, which is a highly conserved ECM protein, has been documented to play pivotal roles in regulating angiogenesis, inflammatory processes and immune responses. The aim of this study was to assess whether mindin contributes to the dev
Autor:
Juan-Juan Qin, Fu-Han Gong, Chun Fang, Zhi-Gang She, Junhong Guo, Zan Huang, Song Tian, Peng Zhang, Zhihua Wang, Hongliang Li, Xueyong Zhu, Wen-Lin Cheng, Jun Gong
Publikováno v:
Circulation. 136:1412-1433
Background: The mechanisms underlying neointima formation remain unclear. Interferon regulatory factors (IRFs), which are key innate immune regulators, play important roles in cardiometabolic diseases. However, the function of IRF4 in arterial resten