Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Fu Kai Hsieh"'
Autor:
Han-Wen Chang, Alexey V. Feofanov, Alexander V. Lyubitelev, Grigory A. Armeev, Elena Y. Kotova, Fu-Kai Hsieh, Mikhail P. Kirpichnikov, Alexey K. Shaytan, Vasily M. Studitsky
Publikováno v:
Cells, Vol 11, Iss 16, p 2475 (2022)
Histone N-terminal tails and their post-translational modifications affect various biological processes, often in a context-specific manner; the underlying mechanisms are poorly studied. Here, the role of individual N-terminal tails of histones H2A/H
Externí odkaz:
https://doaj.org/article/93606d7b46b7459aa3494a6bed92aa5b
Autor:
Elena Y. Kotova, Fu-Kai Hsieh, Han-Wen Chang, Natalia V. Maluchenko, Marie-France Langelier, John M. Pascal, Donal S. Luse, Alexey V. Feofanov, Vasily M. Studitsky
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7107 (2022)
Human poly(ADP)-ribose polymerase-1 (PARP1) is a global regulator of various cellular processes, from DNA repair to gene expression. The underlying mechanism of PARP1 action during transcription remains unclear. Herein, we have studied the role of hu
Externí odkaz:
https://doaj.org/article/7b05caa5d0024687945a868b23e7b4b3
Publikováno v:
International Journal of Biomedicine, Vol 11, Iss Suppl_1, Pp 21-21 (2021)
Background: Nucleosomes are the barriers to transcript elongation by RNA polymerase 2 (Pol 2) in vitro and in vivo. Formation and overcoming the barrier are important for transcription regulation. N-terminal tails of core histones do not affect the i
Externí odkaz:
https://doaj.org/article/228c5869a35d4fb792a60008e7f45878
Autor:
Fu-Kai Hsieh, Sean P. Moran, Alan C. Mullen, Amin Mahpour, Isaac A. Klein, Kaveh Daneshvar, Chan Zhou, Sweta K Gupta, Wenyang Li, Brett M. Cook, Richard A. Young, Arcadia J. Kratkiewicz, Sabrina O L Cancelliere, M. Behfar Ardehali, Joshua V. Pondick, Robert E. Kingston
Publikováno v:
Nat Cell Biol
Cooperation between DNA, RNA and protein regulates gene expression and controls differentiation through interactions that connect regions of nucleic acids and protein domains and through the assembly of biomolecular condensates. Here, we report that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ea0659ff6441def1ba93bf3a3a6692d
https://europepmc.org/articles/PMC8008247/
https://europepmc.org/articles/PMC8008247/
Publikováno v:
Life Science Alliance
Mutations in CHD7 are diagnostic for human CHARGE syndrome. RNAs expressed from the HERVH repeats modulate CHD7 function providing one mechanism for regulation of differentiation of pluripotent cells.
Chd7 encodes an ATP-dependent chromatin remo
Chd7 encodes an ATP-dependent chromatin remo
Publikováno v:
Life Science Alliance; Jan2022, Vol. 5 Issue 1, p1-19, 19p
Publikováno v:
International Journal of Biomedicine, Vol 11, Iss Suppl_1, Pp 21-21 (2021)
Background: Nucleosomes are the barriers to transcript elongation by RNA polymerase 2 (Pol 2) in vitro and in vivo. Formation and overcoming the barrier are important for transcription regulation. N-terminal tails of core histones do not affect the i
Publikováno v:
Methods (San Diego, Calif.).
During transcription along nucleosomal DNA, RNA polymerase II (Pol II) pauses at multiple positions and induces formation of multiple intermediates that aid in maintaining proper chromatin structure. To describe the kinetics of this multiple-step rea
Study of RNA polymerase transcription through nucleosome using the cryo-electron microscopy approach
Autor:
Vasily M. Studitsky, Olga Sokolova, M. G. Karlova, Fu Kai Hsieh, O. I. Volokh, E. S. Trifonova
Publikováno v:
Moscow University Biological Sciences Bulletin. 71:34-38
A promising and reliable method for the analysis of macromolecule structures is capturing images using cryo-electron transmission microscopy and consequently performing three-dimensional reconstructions. In this study, using cryo-electron microscopy,
Publikováno v:
Proceedings of the National Academy of Sciences. 107:11325-11330
Maintenance of the chromatin states and histone modification patterns during transcription is essential for proper gene regulation and cell survival. Histone octamer survives moderate transcription, but is evicted during intense transcription in vivo