Design and Synthesis of 2,3- trans-Proline Analogues as Ligands for Ionotropic Glutamate Receptors and Excitatory Amino Acid Transporters.

Autor: Poulie CBM; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences , University of Copenhagen , Copenhagen 2100 , Denmark., Alcaide A; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences , University of Copenhagen , Copenhagen 2100 , Denmark., Krell-Jørgensen M; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences , University of Copenhagen , Copenhagen 2100 , Denmark., Larsen Y; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences , University of Copenhagen , Copenhagen 2100 , Denmark., Astier E; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences , University of Copenhagen , Copenhagen 2100 , Denmark., Bjørn-Yoshimoto WE; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences , University of Copenhagen , Copenhagen 2100 , Denmark., Yi F; Department of Biomedical and Pharmaceutical Sciences, Center for Structural and Functional Neuroscience, and Center for Biomolecular Structure and Dynamics , University of Montana , Missoula , Montana 59812 , United States., Syrenne JT; Department of Biomedical and Pharmaceutical Sciences, Center for Structural and Functional Neuroscience, and Center for Biomolecular Structure and Dynamics , University of Montana , Missoula , Montana 59812 , United States., Storgaard M; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences , University of Copenhagen , Copenhagen 2100 , Denmark., Nielsen B; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences , University of Copenhagen , Copenhagen 2100 , Denmark., Frydenvang KA; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences , University of Copenhagen , Copenhagen 2100 , Denmark., Jensen AA; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences , University of Copenhagen , Copenhagen 2100 , Denmark., Hansen KB; Department of Biomedical and Pharmaceutical Sciences, Center for Structural and Functional Neuroscience, and Center for Biomolecular Structure and Dynamics , University of Montana , Missoula , Montana 59812 , United States., Pickering DS; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences , University of Copenhagen , Copenhagen 2100 , Denmark., Bunch L; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences , University of Copenhagen , Copenhagen 2100 , Denmark.

Publikováno v: ACS chemical neuroscience [ACS Chem Neurosci] 2019 Jun 19; Vol. 10 (6), pp. 2989-3007. Date of Electronic Publication: 2019 May 24.