Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Fruma Yehiely"'
Autor:
Fruma Yehiely, Paul Bamborough, Maria Da Costa, Billie J. Perry, Gopal Thinakaran, Fred E. Cohen, George A. Carlson, Stanley B. Prusiner
Publikováno v:
Neurobiology of Disease, Vol 3, Iss 4, Pp 339-355 (1997)
Prion diseases are disorders of protein conformation that produce neurodegeneration in humans and animals. Studies of transgenic (Tg) mice indicate that a factor designated protein X is involved in the conversion of the normal cellular prion protein
Externí odkaz:
https://doaj.org/article/88c5f85e9c5644c783be20cde95711f4
Autor:
Fruma Yehiely, Paul Bamborough, Maria Da Costa, Billie J. Perry, Gopal Thinakaran, Fred E. Cohen, George A. Carlson, Stanley B. Prusiner
Publikováno v:
Neurobiology of Disease, Vol 10, Iss 1, Pp 67-68 (2002)
Externí odkaz:
https://doaj.org/article/a53344cae47d4386b6978aed2bdc6b86
Publikováno v:
Cancer Biology & Therapy. 9:825-831
The current therapy of cancer fails to completely and exclusively target tumor cells. An ideal target for cancer therapy should be expressed exclusively in tumor cells and contribute to tumorigenesis. Targeting such a candidate gene would cause cell
Publikováno v:
Journal of Interferon & Cytokine Research. 29:645-656
The GAGE family of highly related tumor antigens is expressed in a variety of tumors. This albeit silent gene expression resulted in resistance of cells to various apoptotic agents such as Fas, interferon-gamma, Taxol, or gamma-radiation. We now repo
Autor:
Robert W. Mahley, Carsten Korth, Charles J. Epstein, Patrick Tremblay, Fred E. Cohen, Darlene Groth, Gültekin Tamgüney, Lennart Mucke, Pauline M. Rudd, Karen H. Ashe, Karl H. Weisgraber, Jan Sap, George A. Carlson, Eric Rubinstein, Kurt Giles, Ina Tesseur, Pamela Stanley, Xiaoping Yang, Richard C. Moore, William A. Kuziel, Raymond A. Dwek, Michael P. Lisanti, Fruma Yehiely, Tony Wyss-Coray, Tracey Dawson Cruz, Claude Boucheix, David V. Glidden, Jörg Tatzelt, Jackob Moskovitz, Holger Wille, Stanley B. Prusiner, Pierre Lessard, Nobuyo Maeda
Publikováno v:
Journal of General Virology. 89:1777-1788
Prion diseases are caused by conversion of a normally folded, non-pathogenic isoform of the prion protein (PrPC) to a misfolded, pathogenic isoform (PrPSc). Prion inoculation experiments in mice expressing homologous PrPCmolecules on different geneti
Autor:
Gamze Karaca, Vincent L. Cryns, Leslie K. Diaz, Feng Chen, Dmitry Turbin, Elizabeth L. Wiley, Michael E. Werner, Charles M. Perou, Joseph R. Evans, Fruma Yehiely, Meiling Lu, Torsten O. Nielsen, Jose V. Moyano
Publikováno v:
Journal of Clinical Investigation. 116:261-270
Recent gene profiling studies have identified a new breast cancer subtype, the basal-like group, which expresses genes characteristic of basal epithelial cells and is associated with poor clinical outcomes. However, the genes responsible for the aggr
Publikováno v:
Cell Cycle. 3:1606-1611
We have previously demonstrated that overexpression of Cell Death Inhibiting RNA (CDIR), a portion of the 3'untranslated region (UTR) of KIAA0425, inhibits Interferon-gamma (IFN-gamma) induced apoptosis in HeLa cells (Shchors et al., J Biol Chem 2002
Publikováno v:
Cancer Biology & Therapy. 1:379-386
Attractive targets for cancer therapy are gene products whose inactivation is not detrimental in essential tissues. The GAGE family of Cancer/Testis Antigens is a group of appealing candidates for cancer therapy since they are expressed in a wide var
Autor:
Paul Bamborough, Frederick Cohen, Fruma Yehiely, Stanley B. Prusiner, Maria Da Costa, Gopal Thinakaran, Billie J. Perry, George A. Carlson
Publikováno v:
Neurobiology of Disease, Vol 3, Iss 4, Pp 339-355 (1997)
Neurobiology of Disease, Vol 10, Iss 1, Pp 67-68 (2002)
Neurobiology of Disease, Vol 10, Iss 1, Pp 67-68 (2002)
Prion diseases are disorders of protein conformation that produce neurodegeneration in humans and animals. Studies of transgenic (Tg) mice indicate that a factor designated protein X is involved in the conversion of the normal cellular prion protein
Autor:
Fred E. Cohen, Paul Bamborough, Fruma Yehiely, Glenn C. Telling, Stanley B. Prusiner, Holger Wille
Publikováno v:
Cold Spring Harbor Symposia on Quantitative Biology. 61:495-509