Výsledky vyhledávání - "Froukje L Ubels"

Effect of Roux-en-Y gastric bypass on the bioavailability of metoprolol from immediate and controlled release tablets: a single oral dose study before and after surgery

Autor: Herman J. Woerdenbag, Marloes Emous, Jan A Apers, Bob Wilffert, Eric N. van Roon, Erik Totté, Jacquelien T. M. Wanders, Henderik W. Frijlink, E. Christiaan Boerma, Froukje L Ubels, Blessing Odigie, Jan Peter Yska

Publikováno v: Eur J Hosp Pharm
European Journal of Hospital Pharmacy: Science and Practice, 27(E1). BMJ PUBLISHING GROUP

Objective Roux-en-Y gastric bypass (RYGB) surgery induces major changes in the gastrointestinal tract that may alter the pharmacokinetics of orally administered drugs. Results from pharmacokinetic studies are sparse. This study aimed to investigate t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90725a0309d4dd863e75cfa00fdacb7d
https://europepmc.org/articles/PMC7147559/

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Redistribution of blood volume in Type I diabetes

Autor: Froukje L. Ubels, J. H. J. Muntinga, AJ Smit, Thera P. Links, Klaas Hoogenberg, W. D. Reitsma, Robin P. F. Dullaart

Publikováno v: Diabetologia. 44:429-432

Aims/hypothesis. Impaired activity of endothelium-derived nitric oxide in Type I (insulin-dependent) diabetes mellitus will cause an increased vascular tone. Considering the lower production of nitric oxide in veins than in arteries, an impaired acti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c007e748fc09dd168107d553c46267f
https://doi.org/10.1007/s001250051639

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Is glycogen storage disease 1a associated with atherosclerosis?

Autor: Joris P. J. Slaets, Froukje L. Ubels, Andries J. Smit, Jan Peter Rake, G. Peter A. Smit

Publikováno v: European Journal of Pediatrics, 161, S62-S64. SPRINGER

Deficiency of microsomal glucose-6-phosphatase in liver and kidney leads to glycogen storage disease type 1a (GSD 1a). Notwithstanding intensive dietary therapy, moderate to severe dyslipidaemia and microalbuminuria, both known atherosclerotic risk f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6550d6270dd094d8868643f07109c026
https://research.rug.nl/en/publications/a76c1c57-b6b0-4fd7-83df-761d8f5669e7

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Effects of initial and long-term lipid-lowering therapy on vascular wall characteristics

Autor: Andries J. Smit, J. H. J. Muntinga, W. D. Reitsma, Froukje L. Ubels, Jasper J. van Doormaal

Publikováno v: Atherosclerosis. 154(1)

Several studies have demonstrated the beneficial effects of 3 hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors on vascular properties, but little is known about treatment intensification. We compared patients in whom statins were st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f29fffbbfe2df0c54bf138aaca09c676
https://pubmed.ncbi.nlm.nih.gov/11137095

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Carotid intima-media thickness: influence of drug treatment and clinical implications

Autor: Andries J. Smit, Froukje L. Ubels, WF Terpstra

Publikováno v: The Netherlands journal of medicine. 55(4)

With B-mode ultrasound measurements of the intima-media thickness (IMT) of the carotid arterial wall (asymptomatic) atherosclerosis can be detected. In this article several studies are reviewed in which IMT was used as a surrogate endpoint to assess

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dbc265bed9a54eef75b4273eb7ed9a3
https://pubmed.ncbi.nlm.nih.gov/10555436

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Walking training for intermittent claudication in diabetes

Autor: Froukje L. Ubels, Andries J. Smit, Thera P. Links, Wj Sluiter, W D Reitsma

Publikováno v: Diabetes care. 22(2)

OBJECTIVE: Walking training (WT) is an established treatment for patients with intermittent claudication (IC). Abnormalities specific to diabetes, such as a relative preponderance of distal lesions and the contribution of microcirculatory disease, mi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6568956845b4b7caca3ef49703df9e1
https://pubmed.ncbi.nlm.nih.gov/10333933

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Alterations in cortisol metabolism in insulin-dependent diabetes mellitus: relationship with metabolic control and estimated blood volume and effect of angiotensin-converting enzyme inhibition

Autor: J. H. J. Muntinga, John J. Pratt, Klaas Hoogenberg, B.G. Wolthers, Andries J. Smit, Wim J. Sluiter, Froukje L. Ubels, Robin P. F. Dullaart

Publikováno v: The Journal of clinical endocrinology and metabolism. 80(10)

11 beta-Hydroxysteroid dehydrogenase (11 beta HSD) catalyzes the interconversion of cortisol and its inactive metabolite, cortisone, and protects the mineralocorticoid receptor from activation by cortisol. Sodium and fluid retention is a well documen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::884e52b99f7f7bc7750d8bb409bf0bf5
https://pubmed.ncbi.nlm.nih.gov/7559888

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