Viruses - a major cause of amyloid deposition in the brain.

Autor: Fulop T; Research Center on Aging, Centre Intégré Universitaire de Santé Et Services Sociaux de l'Estrie-Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada.; Department of Medicine, Division of Geriatrics, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada., Ramassamy C; INRS-Centre Armand-Frappier Santé Biotechnologie, Laval, QC, Canada., Lévesque S; CIUSSS de l'Estrie - CHUS, Sherbrooke, QC, Canada.; Département de Microbiologie Et Infectiologie, Faculté de Médecine Et des Sciences de la santé, Université de Sherbrooke, Sherbrooke, QC, Canada., Frost EH; Département de Microbiologie Et Infectiologie, Faculté de Médecine Et des Sciences de la santé, Université de Sherbrooke, Sherbrooke, QC, Canada., Laurent B; Research Center on Aging, Centre Intégré Universitaire de Santé Et Services Sociaux de l'Estrie-Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada.; Department of Biochemistry and Functional Genomics, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada., Lacombe G; Research Center on Aging, Centre Intégré Universitaire de Santé Et Services Sociaux de l'Estrie-Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada.; Department of Medicine, Division of Geriatrics, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada., Khalil A; Research Center on Aging, Centre Intégré Universitaire de Santé Et Services Sociaux de l'Estrie-Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada.; Department of Medicine, Division of Geriatrics, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada., Larbi A; Department of Medicine, Division of Geriatrics, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada., Hirokawa K; Department of Pathology, Institute of Health and Life Science, Tokyo Medical Dental University, Tokyo and Nito-Memory Nakanosogo Hospital, Tokyo, Japan., Desroches M; MathNeuro Team, Inria Sophia Antipolis Méditerranée, Biot, France.; Université Côte d'Azur, Nice, France., Rodrigues S; Ikerbasque, BCAM, the Basque Foundation for Science and BCAM - The Basque Center for Applied Mathematics, Bilbao, Spain., Bourgade K; Research Center on Aging, Centre Intégré Universitaire de Santé Et Services Sociaux de l'Estrie-Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada., Cohen AA; Department of Environmental Health Sciences, Butler Columbia Aging Center, Mailman School of Public Health, Columbia University, New York, NY, USA., Witkowski JM; Department of Pathophysiology, Medical University of Gdansk, Gdansk, Poland.

Publikováno v: Expert review of neurotherapeutics [Expert Rev Neurother] 2023 Jul-Dec; Vol. 23 (9), pp. 775-790. Date of Electronic Publication: 2023 Aug 09.

Interaction Mechanism Between the HSV-1 Glycoprotein B and the Antimicrobial Peptide Amyloid-β.

Autor: Bourgade K; Research Center on Aging, Geriatric Division, Department of Medicine, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada., Frost EH; Department of Microbiology and Infectious diseases, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada., Dupuis G; Department of Biochemistry, Graduate Program in Immunology, Faculty of Medicine and Health Sciences, University of Sherbrooke, Sherbrooke, QC, Canada., Witkowski JM; Department of Pathophysiology, Medical University of Gdansk, Gdansk, Poland., Laurent B; Research Center on Aging, Department of Biochemistry and Functional Genomics, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada., Calmettes C; INRS-Centre Armand-Frappier Santé-biotechnologie, Laval, QC, Canada., Ramassamy C; INRS-Centre Armand-Frappier Santé-biotechnologie, Laval, QC, Canada., Desroches M; MathNeuro Team, Inria Sophia Antipolis Méditerranée, France.; Université Côte d'Azur, Nice, France., Rodrigues S; Ikerbasque, The Basque Foundation for Science, Bilbao, Spain.; BCAM - The Basque Center for Applied Mathematics, Bilbao, Spain., Fülöp T Jr; Research Center on Aging, Geriatric Division, Department of Medicine, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada.

Publikováno v: Journal of Alzheimer's disease reports [J Alzheimers Dis Rep] 2022 Sep 24; Vol. 6 (1), pp. 599-606. Date of Electronic Publication: 2022 Sep 24 (Print Publication: 2022).

Hyperactivation of monocytes and macrophages in MCI patients contributes to the progression of Alzheimer's disease.

Autor: Munawara U; Research Center on Aging, Faculty of Medicine and Health Sciences, University of Sherbrooke, 3001, 12th Avenue North, Sherbrooke, Quebec, J1H 5N4, Canada., Catanzaro M; Research Center on Aging, Faculty of Medicine and Health Sciences, University of Sherbrooke, 3001, 12th Avenue North, Sherbrooke, Quebec, J1H 5N4, Canada.; Department of Drug Sciences, University of Pavia, Pavia, Italy., Xu W; Singapore Immunology Network (SIgN), Agency for Science Technology and Research (A*STAR), Immunos Building, Biopolis, Singapore, Singapore., Tan C; Singapore Immunology Network (SIgN), Agency for Science Technology and Research (A*STAR), Immunos Building, Biopolis, Singapore, Singapore., Hirokawa K; Department of Diagnostic Pathology, Institute of Health and Life Science, Tokyo Med. Dent. University, Tokyo and Nitobe Memorial Nakanosogo Hospital, Tokyo, Japan., Bosco N; Nestlé Research, Nestlé Institute of Health Sciences, Department of Cell Biology, Cellular Metabolism, EPFL Innovation Park, CH-1015, Lausanne, Switzerland., Dumoulin D; Department of Biology, Faculty of Sciences, University of Sherbrooke, Sherbrooke, Quebec, Canada., Khalil A; Research Center on Aging, Faculty of Medicine and Health Sciences, University of Sherbrooke, 3001, 12th Avenue North, Sherbrooke, Quebec, J1H 5N4, Canada., Larbi A; Research Center on Aging, Faculty of Medicine and Health Sciences, University of Sherbrooke, 3001, 12th Avenue North, Sherbrooke, Quebec, J1H 5N4, Canada.; Singapore Immunology Network (SIgN), Agency for Science Technology and Research (A*STAR), Immunos Building, Biopolis, Singapore, Singapore., Lévesque S; Department of Microbiology and Infectiology, Faculty of Medicine and Health Sciences, University of Sherbrooke, Sherbrooke, Quebec, Canada., Ramassamy C; INRS-Centre Armand-Frappier Santé-biotechnologie, Montréal, Québec, Canada., Barron AE; Department of Bioengineering, Stanford School of Medicine, Stanford, California, USA., Cunnane S; Research Center on Aging, Endocrinology Division, Department of Medicine, Faculty of Medicine and Health Sciences, University of Sherbrooke, Sherbrooke, Quebec, Canada., Beauregard PB; Department of Biology, Faculty of Sciences, University of Sherbrooke, Sherbrooke, Quebec, Canada., Bellenger JP; Department of Chemistry, Faculty of Sciences, University of Sherbrooke, Sherbrooke, Quebec, Canada., Rodrigues S; Ikerbasque, The Basque Foundation for Science, Bilbao, Spain. srodrigues@bcamath.org.; Basque Center for Applied Mathematics, Mathematical, Computational and Experimental Neuroscience research group, Alameda de Mazarredo 14, 48009, Bilbao, Bizkaia, Basque-Country, Spain. srodrigues@bcamath.org., Desroches M; MathNeuro Team, Inria Sophia Antipolis Méditerranée, Valbonne, France.; Université Côte d'Azur, Nice, France., Witkowski JM; Department of Pathophysiology, Medical University of Gdansk, Gdansk, Poland., Laurent B; Research Center on Aging, Department of Biochemistry, Faculty of Medicine and Health Sciences, University of Sherbrooke, Sherbrooke, Quebec, Canada., Frost EH; Department of Microbiology and Infectiology, Faculty of Medicine and Health Sciences, University of Sherbrooke, Sherbrooke, Quebec, Canada., Fulop T; Research Center on Aging, Faculty of Medicine and Health Sciences, University of Sherbrooke, 3001, 12th Avenue North, Sherbrooke, Quebec, J1H 5N4, Canada. Tamas.Fulop@Usherbrooke.ca.

Publikováno v: Immunity & ageing : I & A [Immun Ageing] 2021 Jun 21; Vol. 18 (1), pp. 29. Date of Electronic Publication: 2021 Jun 21.

Comprehensive assessment of cellular senescence in intestinal immunity and biologic therapy response in ulcerative colitis.

Autor: Yao, Baojia¹ (AUTHOR), Zhang, Yawei¹ (AUTHOR), Wu, Qiang¹ (AUTHOR), Yao, Hengchang¹ (AUTHOR), Peng, Liangxin¹ (AUTHOR), Jiang, Zhixian¹ (AUTHOR), Yang, Lichao¹ (AUTHOR) ylc0312@163.com, Yuan, Lianwen¹ (AUTHOR) yuanlianwen@csu.edu.cn

Publikováno v: Scientific Reports. 11/15/2024, Vol. 14 Issue 1, p1-20. 20p.

Targeting Cytokine Release Through the Differential Modulation of Nrf2 and NF-κB Pathways by Electrophilic/Non-Electrophilic Compounds.

Autor: Fagiani F; Department of Drug Sciences, Pharmacology Section, University of Pavia, Pavia, Italy.; Scuola Universitaria Superiore IUSS Pavia, Pavia, Italy., Catanzaro M; Department of Drug Sciences, Pharmacology Section, University of Pavia, Pavia, Italy., Buoso E; Department of Drug Sciences, Pharmacology Section, University of Pavia, Pavia, Italy., Basagni F; Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy., Di Marino D; Department of Life and Environmental Sciences, New York-Marche Structural Biology Center (NY-MaSBiC), Polytechnic University of Marche, Ancona, Italy., Raniolo S; Università della Svizzera Italiana (USI), Faculty of Biomedical Sciences, Institute of Computational Science-Center for Computational Medicine in Cardiology, CH-Lugano, Switzerland., Amadio M; Department of Drug Sciences, Pharmacology Section, University of Pavia, Pavia, Italy., Frost EH; Department of Microbiology and Infectiology, Centre de Recherches Cliniques, Faculty of Medicine and Health Sciences, University of Sherbrooke, Sherbrooke, QC, Canada., Corsini E; Department of Environmental Science and Policy, Università degli Studi di Milano, Milan, Italy., Racchi M; Department of Drug Sciences, Pharmacology Section, University of Pavia, Pavia, Italy., Fulop T; Geriatric Division, Department of Medicine, Faculty of Medicine and Health Sciences, Research Center on Aging, University of Sherbrooke, Sherbrooke, QC, Canada., Govoni S; Department of Drug Sciences, Pharmacology Section, University of Pavia, Pavia, Italy., Rosini M; Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy., Lanni C; Department of Drug Sciences, Pharmacology Section, University of Pavia, Pavia, Italy.

Publikováno v: Frontiers in pharmacology [Front Pharmacol] 2020 Aug 14; Vol. 11, pp. 1256. Date of Electronic Publication: 2020 Aug 14 (Print Publication: 2020).