Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Frondoside A"'
Autor:
Oladapo F. Fagbohun, Joseph P.M. Hui, Junzeng Zhang, Guangling Jiao, H.P. Vasantha Rupasinghe
Publikováno v:
Food Chemistry Advances, Vol 5, Iss , Pp 100748- (2024)
Response Surface Methodology (RSM) and Artificial Neural Network (ANN) were employed to optimize saponin extraction from North Atlantic Sea cucumber (Cucumaria frondosa). Ultrasonication-assisted ethanol-based extractions were used in a second-order
Externí odkaz:
https://doaj.org/article/43fb2bbd17bf499dab8e09ca8954a995
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Cancer remains the leading cause of death worldwide. In spite of significant advances in targeted and immunotherapeutic approaches, clinical outcomes for cancer remain poor. The aim of the present study was to investigate the potential mechanisms and
Externí odkaz:
https://doaj.org/article/cdef98e9ff934b7585bedbe1b2a7f5de
Akademický článek
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Publikováno v:
Marine Drugs, Vol 21, Iss 5, p 262 (2023)
Frondosides are the major saponins (triterpene glycosides) of the North Atlantic sea cucumber (Cucumaria frondosa). Frondosides possess amphiphilic characteristics due to the presence of various hydrophilic sugar moieties and hydrophobic genin (sapog
Externí odkaz:
https://doaj.org/article/e372eda5c3504a708e93a0f9da137d63
Akademický článek
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Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Oligomeric assembly of Amyloid-β (Aβ) is the main toxic species that contribute to early cognitive impairment in Alzheimer’s patients. Therefore, drugs that reduce the formation of Aβ oligomers could halt the disease progression. In this study,
Externí odkaz:
https://doaj.org/article/b8e6f9adcf194f3d927c5d67789ad4b7
Publikováno v:
Molecules, Vol 26, Iss 16, p 4843 (2021)
Parkinson’s disease (PD) is a currently incurable neurodegenerative disorder characterized by the loss of dopaminergic (DAergic) neurons in the substantia nigra pars compacta and α-synuclein aggregation. Accumulated evidence indicates that the sap
Externí odkaz:
https://doaj.org/article/7407f7abb5da4fd989fb4160453442d5
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Introduction: Lung, breast, and colorectal cancers are the leading causes of cancer-related deaths despite many therapeutic options, including targeted therapy and immunotherapies.Methods: Here, we investigated the impact of PTC-209, a small-molecule
Externí odkaz:
https://doaj.org/article/d4a3ce4901e44ff78fd6414a3b72182f
Publikováno v:
Nutrients; Volume 15; Issue 2; Pages: 378
Bladder cancer is a highly recurrent disease and a common cause of cancer-related deaths worldwide. Despite recent developments in diagnosis and therapy, the clinical outcome of bladder cancer remains poor; therefore, novel anti-bladder cancer drugs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7593de7678c485874805dc990951d405
Publikováno v:
Marine Drugs, Vol 18, Iss 2, p 111 (2020)
Background: The marine-derived triterpenoid frondoside A inhibits the phosphatidylinositol-3-kinase (PI3K) pathway in cancer cells. Because this pathway is also crucially involved in platelet activation, we studied the effect of frondoside A on throm
Externí odkaz:
https://doaj.org/article/a857090e697f47c092fe2064c6fc7c99