Discovery of Small-Molecule Antibiotics against a Unique tRNA-Mediated Regulation of Transcription in Gram-Positive Bacteria.

Autor: Frohlich KM; The RNA Institute and the Department of Biological Sciences, University at Albany - State University of New York, 1400 Washington Avenue, Albany, NY, 12222, USA.; Current address: Regeneron Inc., Rensselaer, NY, USA., Weintraub SF; The RNA Institute and the Department of Biological Sciences, University at Albany - State University of New York, 1400 Washington Avenue, Albany, NY, 12222, USA.; Current address: New York Medical College, Valhalla, NY, USA., Bell JT; The RNA Institute and the Department of Biological Sciences, University at Albany - State University of New York, 1400 Washington Avenue, Albany, NY, 12222, USA.; Current address: Albany Medical College, Center for Physician Assistant Studies, Albany, NY, USA., Todd GC; The RNA Institute and the Department of Biological Sciences, University at Albany - State University of New York, 1400 Washington Avenue, Albany, NY, 12222, USA., Väre VYP; The RNA Institute and the Department of Biological Sciences, University at Albany - State University of New York, 1400 Washington Avenue, Albany, NY, 12222, USA., Schneider R; Department of Biomedical Sciences, School of Public Health, University at Albany - State University of New York, P.O. Box 22002, Albany, NY, 12201, USA., Kloos ZA; The RNA Institute and the Department of Biological Sciences, University at Albany - State University of New York, 1400 Washington Avenue, Albany, NY, 12222, USA.; Division of Infectious Diseases, Wadsworth Center, New York State Department of Health, P.O. Box 22002, Albany, NY, 12201-2002, USA.; Current address: Molecular, Cellular and Developmental Biology, Yale University, West Haven, CT, USA., Tabe ES; Division of Infectious Diseases, Wadsworth Center, New York State Department of Health, P.O. Box 22002, Albany, NY, 12201-2002, USA.; Current address: Albany College of Pharmacy and Health Sciences, Albany, NY, USA., Cantara WA; The RNA Institute and the Department of Biological Sciences, University at Albany - State University of New York, 1400 Washington Avenue, Albany, NY, 12222, USA.; Current address: Chemistry and Biochemistry, Ohio State University, Columbus, OH, USA., Stark CJ; The RNA Institute and the Department of Biological Sciences, University at Albany - State University of New York, 1400 Washington Avenue, Albany, NY, 12222, USA., Onwuanaibe UJ; The RNA Institute and the Department of Biological Sciences, University at Albany - State University of New York, 1400 Washington Avenue, Albany, NY, 12222, USA., Duffy BC; Albany Molecular Research Incorporated, 26 Corporate Circle, Albany, NY, 12203, USA.; Current address: New York State Department of Health, Albany, NY, USA., Basanta-Sanchez M; The RNA Institute and the Department of Biological Sciences, University at Albany - State University of New York, 1400 Washington Avenue, Albany, NY, 12222, USA.; Current address: Waters Corporation, Pleasanton, CA, USA., Kitchen DB; Albany Molecular Research Incorporated, 26 Corporate Circle, Albany, NY, 12203, USA., McDonough KA; Department of Biomedical Sciences, School of Public Health, University at Albany - State University of New York, P.O. Box 22002, Albany, NY, 12201, USA.; Division of Infectious Diseases, Wadsworth Center, New York State Department of Health, P.O. Box 22002, Albany, NY, 12201-2002, USA., Agris PF; The RNA Institute and the Department of Biological Sciences, University at Albany - State University of New York, 1400 Washington Avenue, Albany, NY, 12222, USA.; Current address: Duke University, Medical School, Durham, NC, USA.

Publikováno v: ChemMedChem [ChemMedChem] 2019 Apr 03; Vol. 14 (7), pp. 758-769. Date of Electronic Publication: 2019 Mar 01.

Evidence That Antibiotics Bind to Human Mitochondrial Ribosomal RNA Has Implications for Aminoglycoside Toxicity.

Autor: Hong S; From The RNA Institute and the Department of Biological Sciences, University at Albany, Albany, New York 12222., Harris KA; From The RNA Institute and the Department of Biological Sciences, University at Albany, Albany, New York 12222., Fanning KD; From The RNA Institute and the Department of Biological Sciences, University at Albany, Albany, New York 12222., Sarachan KL; From The RNA Institute and the Department of Biological Sciences, University at Albany, Albany, New York 12222., Frohlich KM; From The RNA Institute and the Department of Biological Sciences, University at Albany, Albany, New York 12222., Agris PF; From The RNA Institute and the Department of Biological Sciences, University at Albany, Albany, New York 12222 pagris@albany.edu.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2015 Jul 31; Vol. 290 (31), pp. 19273-86. Date of Electronic Publication: 2015 Jun 09.

Membrane vesicle production by Chlamydia trachomatis as an adaptive response.

Autor: Frohlich KM; Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center New Orleans, LA, USA., Hua Z; Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center New Orleans, LA, USA ; Department of Neonatology, Ministry of Education Key Laboratory of Child Development and Disorder, The Children's Hospital, Chongqing Medical University Chongqing, China., Quayle AJ; Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center New Orleans, LA, USA., Wang J; Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center New Orleans, LA, USA., Lewis ME; Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center New Orleans, LA, USA., Chou CW; Department of Chemistry, University of Georgia Athens, GA, USA., Luo M; Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center New Orleans, LA, USA., Buckner LR; Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center New Orleans, LA, USA., Shen L; Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center New Orleans, LA, USA.

Publikováno v: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2014 Jun 10; Vol. 4, pp. 73. Date of Electronic Publication: 2014 Jun 10 (Print Publication: 2014).

Altered protein secretion of Chlamydia trachomatis in persistently infected human endocervical epithelial cells.

Autor: Wang J; Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA., Frohlich KM; Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA., Buckner L; Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA., Quayle AJ; Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA., Luo M; Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA., Feng X; Department of Molecular Biology and Biochemistry, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA., Beatty W; Department of Molecular Microbiology, Washington University School of Medicine, St Louis, MO 63110, USA., Hua Z; Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA., Rao X; Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA., Lewis ME; Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA., Sorrells K; Department of Pathology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA., Santiago K; Department of Pathology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA., Zhong G; Department of Microbiology and Immunology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA., Shen L; Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.

Publikováno v: Microbiology (Reading, England) [Microbiology (Reading)] 2011 Oct; Vol. 157 (Pt 10), pp. 2759-2771. Date of Electronic Publication: 2011 Jul 07.