Zobrazeno 1 - 10 of 236 pro vyhledávání: '"Frizler M"'
1
Synthesis and preliminary radiopharmacological characterisation of an 11C-labelled azadipeptide nitrile as potential PET tracer for imaging of cysteine cathepsins
Autor: Laube, M., Frizler, M., Wodtke, R., Neuber, C., Belter, B., Kniess, T., Bachmann, M., Gütschow, M., Pietzsch, J., Löser, R.
Publikováno v: Journal of Labelled Compounds and Radiopharmaceuticals 62(2019)8, 448-459
An O-methyltyrosine-containing azadipeptide nitrile was synthesised and investigated for its inhibitory activity towards cathepsins L, S, K and B. Labelling with carbon-11 was accomplished by reaction of the corresponding phenolic precursor with [11C
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4577::21c47044460fb7dd29a66a6e1b84eaca
https://www.hzdr.de/publications/Publ-28661-1
Zobrazit plný text záznamu
3
Einführung einer geänderten Formulierung von Levothyroxin-Tabletten der Firma Merck (Euthyrox®)
Autor: Paesler, J., Frizler, M., Grüger, T.
Publikováno v: Bulletin zur Arzneimittelsicherheit, 2018(3):4-10
Das Bundesinstitut für Arzneimittel und Medizinprodukte (BfArM) hat im Juli 2018 innerhalb eines europäischen Worksharing-Variation-Verfahrens gemeinsam mit den anderen beteiligten EU-Mitgliedstaaten positiv über die geplante Einführung einer ge
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3694::ee3312c374863b429a8dc69ffdbda3e0
https://www.bfarm.de/DE/Aktuelles/Publikationen/Bulletin/Archiv/_node.html#Start
Zobrazit plný text záznamu
5
Active Site Mapping of Human Cathepsin F with Dipeptide Nitrile Inhibitors
Autor: Schmitz, J., Furtmann, N., Ponert, M., Frizler, M., Löser, R., Bartz, U., Bajorath, J., Gütschow, M.
Publikováno v: ChemMedChem 10(2015)8, 1365-1377
The cleavage of the invariant chain is the key event in the trafficking pathway of major histocompatibility complex class II. Cathepsin S constitutes the major processing enzyme of the invariant chain, but cathepsin F acts in macrophages as its funct
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4577::1240d77541d70e7060c1896beb58ed7c
https://www.hzdr.de/publications/Publ-22102-1
Zobrazit plný text záznamu
6
Radiopharmacological characterisation of an 18F-labelled azadipeptide nitrile as novel probe for molecular imaging of the tumour-associated cathepsin activity
Autor: Löser, R., Bergmann, R., Frizler, M., Mosch, B., Steinbach, J., Gütschow, M., Pietzsch, J.
Publikováno v: 20th International Symposium on Radiopharmaceutical Sciences (ISRS), 12.-17.05.2013, Jeju, Korea
Journal of Labelled Compounds and Radiopharmaceuticals 56(2013), S390
Objectives: The molecular processes leading to tumour invasion and metastasis are closely associated with a network of intra- and extracellular proteolysis. A prominent role in this network was assigned to the thioldependent cathepsins [1]. Among thi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9863c04b2d0339b01e1ed385ac2dd5e3
https://www.hzdr.de/publications/Publ-19013-1
Zobrazit plný text záznamu
7
Synthesis and radiopharmacological characterisation of a fluorine-18 labelled azadipeptide nitrile as potential PET Tracer for in vivo imaging of cysteine cathepsins
Autor: Löser, R., Bergmann, R., Frizler, M., Mosch, B., Dombrowski, L., Kuchar, M., Steinbach, J., Gütschow, M., Pietzsch, J.
Publikováno v: ChemMedChem 8(2013), 1330-1344
A fluorinated cathepsin inhibitor based on the azadipeptide nitrile chemotype was prepared and selected for PET tracer development owing to its high affinity for the oncologically relevant cathepsins L, S, K and B. Labelling with fluorine-18 was acco
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4577::243233ff9ae420766239fcbe6e81af01
https://www.hzdr.de/publications/Publ-18783-1
Zobrazit plný text záznamu
8
Akademický článek
Synthesis and preliminary radiopharmacological characterisation of an 11 C-labelled azadipeptide nitrile as potential PET tracer for imaging of cysteine cathepsins.
Autor: Laube M; Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany., Frizler M; Pharmaceutical Institute, Pharmaceutical Chemistry I, Rheinische Friedrich-Wilhelms-Universität, Bonn, Germany., Wodtke R; Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany., Neuber C; Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany., Belter B; Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany., Kniess T; Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany., Bachmann M; Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany., Gütschow M; Pharmaceutical Institute, Pharmaceutical Chemistry I, Rheinische Friedrich-Wilhelms-Universität, Bonn, Germany., Pietzsch J; Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany.; Faculty of Chemistry and Food Chemistry, School of Science, Technische Universität Dresden, Dresden, Germany., Löser R; Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany.; Faculty of Chemistry and Food Chemistry, School of Science, Technische Universität Dresden, Dresden, Germany.
Publikováno v: Journal of labelled compounds & radiopharmaceuticals [J Labelled Comp Radiopharm] 2019 Jun 30; Vol. 62 (8), pp. 448-459. Date of Electronic Publication: 2019 May 15.
Zobrazit plný text záznamu
9
Akademický článek
Unveiling the Roles of Cysteine Proteinases F and W: From Structure to Pathological Implications and Therapeutic Targets.
Autor: Zdravkova, Kristina1 (AUTHOR) jakovlevak@hotmail.com, Mijanovic, Olja2 (AUTHOR) olja.mijanovic@gmail.com, Brankovic, Ana3 (AUTHOR) ana.brankovic@kpu.edu.rs, Ilicheva, Polina M.4 (AUTHOR) ilichevapm@gmail.com, Jakovleva, Aleksandra5 (AUTHOR) aleksandrajakovleva@hotmail.com, Karanovic, Jelena6 (AUTHOR) jelena.karanovic@imgge.bg.ac.rs, Pualic, Milena7 (AUTHOR) milenamijan@gmail.com, Pualic, Dusan8 (AUTHOR) pualic.d@gmail.com, Rubel, Aleksandr A.9 (AUTHOR) a.rubel@spbu.ru, Savvateeva, Lyudmila V.10 (AUTHOR) ludmilaslv@yandex.ru, Parodi, Alessandro11 (AUTHOR) aparodi.sechenovuniversity@gmail.com, Zamyatnin Jr., Andrey A.12,13 (AUTHOR) zamyat@belozersky.msu.ru
Publikováno v: Cells (2073-4409). Jun2024, Vol. 13 Issue 11, p917. 18p.
Zobrazit plný text záznamu
10
Akademický článek
Design and Synthesis of Multi-Functional Ligands through Hantzsch Reaction: Targeting Ca 2+ Channels, Activating Nrf2 and Possessing Cathepsin S Inhibitory, and Antioxidant Properties.
Autor: Pachón-Angona, Irene1,2 (AUTHOR) mjoset@ucm.es, Bernard, Paul J.1 (AUTHOR) paul.bernard@univ-fcomte.fr, Simakov, Alexey3 (AUTHOR) aleksei.simakov@univ-fcomte.fr, Maj, Maciej4 (AUTHOR) maciej.maj@umlub.pl, Jozwiak, Krzysztof4 (AUTHOR) krzysztof.jozwiak@umlub.pl, Novotna, Anna5 (AUTHOR) novo.anna21@gmail.com, Lemke, Carina5 (AUTHOR) wirtzcarina01@gmail.com, Gütschow, Michael5 (AUTHOR) guetschow@uni-bonn.de, Martin, Helene3 (AUTHOR) helene.martin@univ-fcomte.fr, Oset-Gasque, María-Jesús2,6 (AUTHOR), Contelles, José-Marco7,8 (AUTHOR) iqoc21@iqog.csic.es, Ismaili, Lhassane1 (AUTHOR) iqoc21@iqog.csic.es
Publikováno v: Pharmaceutics. Jan2024, Vol. 16 Issue 1, p121. 14p.
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje