Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Fritz Struber"'
Publikováno v:
Organic Process Research & Development. 11:341-345
The manufacturing process for lumefantrine, 2, one of the two active principles in the fixed-dose combination of the antimalarial drug Coartem, was reworked. For the conversion of 2-chloro-1-(2,7-dichloro-9H-fluoren-4-yl)ethanone, 5, to 2-dibutylamin
Autor:
Markus Bänziger, Hans Hirt, Christophe Malan, Kurt Laumen, Troxler Thomas J, Felix Spindler, Jacques Cercus, Fritz Struber
Publikováno v:
Tetrahedron: Asymmetry. 14:3469-3477
The decahydroisoquinoline derivative NVP-ACQ090 is a potent and selective antagonist at the somatostatin sst3 receptor. The original research synthesis of NVP-ACQ090 comprises a main chain of nine linear steps and two side chains of three and steps,
Publikováno v:
The Journal of Organic Chemistry. 64:6252-6256
The templating effect of potassium ions on the ionophore antibiotic X-206 (1) ensured that most of the hydroxy, hemiacetal, and ether groups were involved in encapsulation of the metal atom, which allowed a selective derivatization at the unbound C(2
Publikováno v:
Helvetica Chimica Acta. 81:812-827
The insecticidal polyether antibiotic X-206 (1) complexes potassium ions using nearly all of its O-atoms either for binding to the metal ion or for participation in a H-bonding network which helps to hold X-206 in the ionophoric tertiary structure. T
Autor:
Fritz Struber, Yasuchika Yamaguchi, Tammo Winkler, Kurt Nebel, Anthony Cornelius O'sullivan, Haukur Kristinsson
Publikováno v:
Tetrahedron. 50:6825-6838
The sulfamoylated ribose derivative 8 was prepared on a kilogram scale, and used in conjunction with various heterocycles to prepare a series of natural and unnatural 5-O-sulfamoyl nucleosides ( 10 – 32 ). A modification of the Vorbruggen-Hilbert-J
Autor:
Yasuchika Yamaguchi, Fritz Struber, Tammo Winkler, Haukur Kristinsson, Anthony Cornelius O'sullivan, Kurt Nebel
Publikováno v:
ChemInform. 25
The sulfamoylated ribose derivative 8 was prepared on a kilogram scale, and used in conjunction with various heterocycles to prepare a series of natural and unnatural 5-O-sulfamoyl nucleosides ( 10 – 32 ). A modification of the Vorbruggen-Hilbert-J
Autor:
Fritz Struber, Michael Mutz, Katrin Fiebich, Aldo Hoermann, Alfred Rindlisbacher, Anthony Cornelius O'sullivan
Publikováno v:
Pesticide Science. 55:379-381
The naturally-occurring ionophore X206, originally isolated for its antibacterial activity, also exhibits broad insecticidal and acaricidal activity. This summary reports structure/activity studies with X206 and 34 derivatives as well as mode of acti
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 9(11)
Starting from polystyrene, a simple four-step synthesis of polymer- supported alkyltriazenes (alkyl Me, Et, benzyl) is described. With this syn- thesis, a loading capacity of 2.2 mmol g 1 can be reached. The most prominent application of these polyme
Publikováno v:
Chemistry - A European Journal; Jun2003, Vol. 9 Issue 11, p2582-2588, 7p