Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Fritz Lauterbach"'
Publikováno v:
Biochemical Pharmacology. 46:1339-1347
Compartmentation of 1-naphthol metabolism was inferred from the metabolite pattern and distribution in the isolated mucosa of guinea pig intestine mounted in a flux chamber (Sund and Lauterbach, Arch Pharmacol Toxicol58: 74–83, 1986). To verify the
Autor:
Fritz Lauterbach, Reidar Bredo Sund
Publikováno v:
Pharmacologytoxicology. 72(2)
As an extension of a previous study on the metabolism of 14C-1-naphthol (1-N) by the isolated guinea pig mucosa (Sund & Lauterbach 1986), the isomeric compound 2-naphthol (2-N, 50-130 nmol/ml) has now been examined. 14C-Labelled drug was added to the
Autor:
Wolf H. Kunau, Fritz Lauterbach
Publikováno v:
FEBS Letters. 94:120-124
Autor:
Fritz Lauterbach, Reidar Bredo Sund
Publikováno v:
Pharmacology & Toxicology. 60:262-268
A previous study (Sund & Lauterbach 1986) in the isolated guinea pig mucosa showed a complex pattern of 1-naphthol (I) metabolism and metabolite (glucuronide = II and sulphate = III) transport in relation to tissue studied (jejunum and colon) and adm
Autor:
Fritz Lauterbach, Klaus Turnheim
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 299:201-205
In anaesthetized guinea pigs N-(3H)methylscopolamine (NMScop), N1-(14C)methylnicotinamide (NMN), and (14C)tetraethylammonium (TEA), administered intravenously, were secreted against a concentration gradient into the lumen of the small intestine. The
Publikováno v:
Biochemical Pharmacology. 26:763-767
In order to localize the previously demonstrated intestinal transport mechanism for quaternary ammonium compounds, counter-transport and efflux experiments were performed with N -methyl-scopolamine (NMScop) on isolated jejunal epithelia of guinea pig
Autor:
Fritz Lauterbach, K. Turnheim
Publikováno v:
Biochemical Pharmacology. 26:99-108
The transepithelial permeation and the cellular uptake of N -methylscopolamine (NMScop), N 1 -methylnicotinamide (NMN), and tetraethylammonium (TEA) were studied in the isolated jejunal mucosa of the guinea pig. (1). The permeation rate, corrected fo
Publikováno v:
Naunyn-Schmiedebergs Archiv f�r Experimentelle Pathologie und Pharmakologie. 247:71-86
Mittels in vitro-Methoden wurden die Veranderungen untersucht, denen die Aldehydgruppe des Strophanthidins und seiner Glykoside im tierischen Stoffwechsel unterliegt. Gewebsschnitte und -homogenate aus Rattenleber reduzieren die 19-Oxo-Cardenolide St
Publikováno v:
Naunyn-Schmiedebergs Archiv für Experimentelle Pathologie und Pharmakologie. 247:391-411
Autor:
Fritz Lauterbach
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 150:146-155
1. 1. The dependence of the penetration of cortisol and convallatoxin (strophanthidin-α- l -rhamnoside) from the site of administration (mucosal or serosal solution) and from the steroid concentration was studied in the perfused small intestine of t