Zobrazeno 1 - 10
of 208
pro vyhledávání: '"Fritz Krombach"'
Autor:
Vittorio Fortino, Pia Anneli Sofia Kinaret, Michele Fratello, Angela Serra, Laura Aliisa Saarimäki, Audrey Gallud, Govind Gupta, Gerard Vales, Manuel Correia, Omid Rasool, Jimmy Ytterberg, Marco Monopoli, Tiina Skoog, Peter Ritchie, Sergio Moya, Socorro Vázquez-Campos, Richard Handy, Roland Grafström, Lang Tran, Roman Zubarev, Riitta Lahesmaa, Kenneth Dawson, Katrin Loeschner, Erik Husfeldt Larsen, Fritz Krombach, Hannu Norppa, Juha Kere, Kai Savolainen, Harri Alenius, Bengt Fadeel, Dario Greco
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Nanomaterials have a range of potential applications, however, toxicity remains a concern, limiting application and requiring extensive testing. Here, the authors report on a predictive framework made using a range of tests linking materials properti
Externí odkaz:
https://doaj.org/article/cd868a81e9ec4d95b4b5c073cf9197e3
Autor:
Bernd Uhl, Laura AMittmann, Julian Dominik, Roman Hennel, Bojan Smiljanov, Florian Haring, Johanna BSchaubächer, Constanze Braun, Lena Padovan, Robert Pick, Martin Canis, Christian Schulz, Matthias Mack, Ewgenija Gutjahr, Peter Sinn, Jörg Heil, Katja Steiger, Sandip M Kanse, Wilko Weichert, Markus Sperandio, Kirsten Lauber, Fritz Krombach, Christoph A Reichel
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 6, Pp n/a-n/a (2021)
Abstract High intratumoral levels of urokinase‐type plasminogen activator (uPA)‐plasminogen activator inhibitor‐1 (PAI‐1) heteromers predict impaired survival and treatment response in early breast cancer. The pathogenetic role of this protei
Externí odkaz:
https://doaj.org/article/4c70973c2a744ff8b94cdcdb9b282bf8
Autor:
Gabriele Zuchtriegel, Bernd Uhl, Robert Pick, Michaela Ramsauer, Julian Dominik, Laura A. Mittmann, Martin Canis, Sandip Kanse, Markus Sperandio, Fritz Krombach, Christoph A. Reichel
Publikováno v:
Haematologica, Vol 106, Iss 10 (2020)
The recruitment of neutrophils from the microvasculature to the site of injury or infection represents a key event in the inflammatory response. Vitronectin (VN) is a multifunctional macromolecule abundantly present in blood and extracellular matrix.
Externí odkaz:
https://doaj.org/article/8d9ad4479b9e45e684bcfe0a8b6d74ae
Autor:
Koustav Ganguly, Dariusch Ettehadieh, Swapna Upadhyay, Shinji Takenaka, Thure Adler, Erwin Karg, Fritz Krombach, Wolfgang G. Kreyling, Holger Schulz, Otmar Schmid, Tobias Stoeger
Publikováno v:
Particle and Fibre Toxicology, Vol 14, Iss 1, Pp 1-17 (2017)
Abstract Background The death toll associated with inhaled ambient particulate matter (PM) is attributed mainly to cardio-vascular rather than pulmonary effects. However, it is unclear whether the key event for cardiovascular impairment is particle t
Externí odkaz:
https://doaj.org/article/0ff2c684a8854b1d88d863f13e13f576
Autor:
Stephanie Hirn, Nadine Haberl, Kateryna Loza, Matthias Epple, Wolfgang G. Kreyling, Barbara Rothen-Rutishauser, Markus Rehberg, Fritz Krombach
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 5, Iss 1, Pp 2440-2449 (2014)
Precision-cut lung slices (PCLS) are an established ex vivo alternative to in vivo experiments in pharmacotoxicology. The aim of this study was to evaluate the potential of PCLS as a tool in nanotoxicology studies. Silver (Ag-NPs) and zinc oxide (ZnO
Externí odkaz:
https://doaj.org/article/99327795fc3d403a9759f6c5dbc9cb9f
Autor:
Sebastian Ahlberg, Alexandra Antonopulos, Jörg Diendorf, Ralf Dringen, Matthias Epple, Rebekka Flöck, Wolfgang Goedecke, Christina Graf, Nadine Haberl, Jens Helmlinger, Fabian Herzog, Frederike Heuer, Stephanie Hirn, Christian Johannes, Stefanie Kittler, Manfred Köller, Katrin Korn, Wolfgang G. Kreyling, Fritz Krombach, Jürgen Lademann, Kateryna Loza, Eva M. Luther, Marcelina Malissek, Martina C. Meinke, Daniel Nordmeyer, Anne Pailliart, Jörg Raabe, Fiorenza Rancan, Barbara Rothen-Rutishauser, Eckart Rühl, Carsten Schleh, Andreas Seibel, Christina Sengstock, Lennart Treuel, Annika Vogt, Katrin Weber, Reinhard Zellner
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 5, Iss 1, Pp 1944-1965 (2014)
PVP-capped silver nanoparticles with a diameter of the metallic core of 70 nm, a hydrodynamic diameter of 120 nm and a zeta potential of −20 mV were prepared and investigated with regard to their biological activity. This review summarizes the phys
Externí odkaz:
https://doaj.org/article/9ff9b4c808fe4650a9603784c6b22761
Autor:
Nadine Haberl, Stephanie Hirn, Alexander Wenk, Jörg Diendorf, Matthias Epple, Blair D. Johnston, Fritz Krombach, Wolfgang G. Kreyling, Carsten Schleh
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 4, Iss 1, Pp 933-940 (2013)
Silver nanoparticles (AgNP) are among the most promising nanomaterials, and their usage in medical applications and consumer products is growing rapidly. To evaluate possible adverse health effects, especially to the lungs, the current study focused
Externí odkaz:
https://doaj.org/article/4308fd00125344619caa36dc08835715
Autor:
Gabriele Zuchtriegel, Bernd Uhl, Daniel Puhr-Westerheide, Michaela Pörnbacher, Kirsten Lauber, Fritz Krombach, Christoph Andreas Reichel
Publikováno v:
PLoS Biology, Vol 14, Iss 5, p e1002459 (2016)
Effective immune responses require the directed migration of leukocytes from the vasculature to the site of injury or infection. How immune cells "find" their site of extravasation remains largely obscure. Here, we identified a previously unrecognize
Externí odkaz:
https://doaj.org/article/f5795824501c4e4ea51d294bc8cf3df4
Autor:
Christoph A Reichel, Maximilian E T Hessenauer, Kerstin Pflieger, Markus Rehberg, Sandip M Kanse, Stefan Zahler, Fritz Krombach, Alexander Berghaus, Sebastian Strieth
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0116883 (2015)
Rapid fibrovascularization is a prerequisite for successful biomaterial engraftment. In addition to their well-known roles in fibrinolysis, urokinase-type plasminogen activator (uPA) and tissue plasminogen activator (tPA) or their inhibitor plasminog
Externí odkaz:
https://doaj.org/article/e481b81df87b4b4e82b831b0194ae9d9
Autor:
Christoph A Reichel, Max Lerchenberger, Bernd Uhl, Markus Rehberg, Nina Berberich, Stefan Zahler, Matthias P Wymann, Fritz Krombach
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17229 (2011)
Clinical trials revealed beneficial effects of the broad-spectrum serine protease inhibitor aprotinin on the prevention of ischemia-reperfusion (I/R) injury. The underlying mechanisms remained largely unclear. Using in vivo microscopy on the cremaste
Externí odkaz:
https://doaj.org/article/9f20a55c123c4dfeae4eefe5ebad8b90