Zobrazeno 1 - 10
of 227
pro vyhledávání: '"Fritz Jänicke"'
Autor:
Christoph Thomssen, Martina Vetter, Eva J. Kantelhardt, Christoph Meisner, Marcus Schmidt, Pierre M. Martin, Florian Clatot, Doris Augustin, Volker Hanf, Daniela Paepke, Wolfgang Meinerz, Gerald Hoffmann, Wolfgang Wiest, Fred C. G. J. Sweep, Manfred Schmitt, Fritz Jänicke, Sibylle Loibl, Gunter von Minckwitz, Nadia Harbeck
Publikováno v:
Cancers, Vol 15, Iss 5, p 1580 (2023)
Background: In node-negative breast cancer (NNBC), a high risk of recurrence is determined by clinico-pathological or tumor-biological assessment. Taxanes may improve adjuvant chemotherapy. Methods: NNBC 3-Europe, the first randomized phase-3 trial i
Externí odkaz:
https://doaj.org/article/a0738e9a40d749a1aadfdd14436190b8
Autor:
Gottfried E. Konecny, Dennis J. Slamon, Gerrit Los, Fritz Jänicke, Nitin Udar, Sugandha Dandekar, Hong-Mei Rong, Natarajan Venkatesan, Victor E. Velculescu, Siân Jones, Boris Winterhoff, Alexandra Meuter, Charles Ginther, Lee Anderson, Judy Dering, Meenal Chalukya, Kanthinh Manivong, Jing Wei Qi, Teodora Kolarova, Christine zu Eulenburg, Maike Ihnen
PDF file - 603K, Supplemental Figure S1: Gene maps of the BRCA1 (A) and BRCA2 (B) CpG islands examined with bisulfite pyrosequencing. Supplemental Figure S2: Anchorage independent growth inhibition at 1μM rucaparib in soft agar. Of the 39 tested ova
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3df54f80fb3880b007f62b7f6bbc31c4
https://doi.org/10.1158/1535-7163.22500252
https://doi.org/10.1158/1535-7163.22500252
Autor:
Gottfried E. Konecny, Dennis J. Slamon, Gerrit Los, Fritz Jänicke, Nitin Udar, Sugandha Dandekar, Hong-Mei Rong, Natarajan Venkatesan, Victor E. Velculescu, Siân Jones, Boris Winterhoff, Alexandra Meuter, Charles Ginther, Lee Anderson, Judy Dering, Meenal Chalukya, Kanthinh Manivong, Jing Wei Qi, Teodora Kolarova, Christine zu Eulenburg, Maike Ihnen
Here, we investigate the potential role of the PARP inhibitor rucaparib (CO-338, formerly known as AG014699 and PF-01367338) for the treatment of sporadic ovarian cancer. We studied the growth inhibitory effects of rucaparib in a panel of 39 ovarian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbeee4da3ffc16ade9b2433aa2b60aae
https://doi.org/10.1158/1535-7163.c.6536409.v1
https://doi.org/10.1158/1535-7163.c.6536409.v1
Autor:
Gottfried E. Konecny, Dennis J. Slamon, Gerrit Los, Fritz Jänicke, Nitin Udar, Sugandha Dandekar, Hong-Mei Rong, Natarajan Venkatesan, Victor E. Velculescu, Siân Jones, Boris Winterhoff, Alexandra Meuter, Charles Ginther, Lee Anderson, Judy Dering, Meenal Chalukya, Kanthinh Manivong, Jing Wei Qi, Teodora Kolarova, Christine zu Eulenburg, Maike Ihnen
PDF file - 66K, Cell lines and culture media.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10249e54d733f8ff8e4066b47d2df516
https://doi.org/10.1158/1535-7163.22500249.v1
https://doi.org/10.1158/1535-7163.22500249.v1
Autor:
Michael Gnant, Mathias Gehrmann, Ralf Kronenwett, Guido Hennig, Inke S. Feder, Karsten E. Weber, Peter Fritz, Matthias Schwab, Hiltrud Brauch, Werner Schroth, Manfred Kaufmann, Achim Rody, Heinz Kölbl, Marcus Schmidt, Fritz Jänicke, Volkmar Müller, Christa Freibauer, Paul Sevelda, Andrea Jelen, Richard Greil, Otto Dietze, Christian F. Singer, Florian Fitzal, Peter Dubsky, Raimund Jakesz, Margaretha Rudas, Martin Filipits
PDF file - 299K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a16d9f1e992a0a0b58b9afe181fc3478
https://doi.org/10.1158/1078-0432.22442498
https://doi.org/10.1158/1078-0432.22442498
Autor:
Michael Gnant, Mathias Gehrmann, Ralf Kronenwett, Guido Hennig, Inke S. Feder, Karsten E. Weber, Peter Fritz, Matthias Schwab, Hiltrud Brauch, Werner Schroth, Manfred Kaufmann, Achim Rody, Heinz Kölbl, Marcus Schmidt, Fritz Jänicke, Volkmar Müller, Christa Freibauer, Paul Sevelda, Andrea Jelen, Richard Greil, Otto Dietze, Christian F. Singer, Florian Fitzal, Peter Dubsky, Raimund Jakesz, Margaretha Rudas, Martin Filipits
Purpose: According to current guidelines, molecular tests predicting the outcome of breast cancer patients can be used to assist in making treatment decisions after consideration of conventional markers. We developed and validated a gene expression s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20b7874bf5e6167082f9f95131857003
https://doi.org/10.1158/1078-0432.c.6519212.v1
https://doi.org/10.1158/1078-0432.c.6519212.v1
Autor:
Peter Paluchowski, Guido Sauter, Andreas Marx, Luigi Terracciano, Eike Burandt, Ronald Simon, Alexander Quaas, Fritz Jänicke, Patrick Lebok, Volkmar Müller, Uwe Heilenkötter, Annette Lebeau, Christian Wilke, Julia Huber, Stefan Geist
Publikováno v:
Molecular Medicine Reports
Angiogenesis is a key process in tumor growth and progression, which is controlled by vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs). In order to better understand the prevalence and prognostic value of VEGFR1 expression in
Autor:
Sven Mahner, Katharina Möller, Stefan Geist, Cansu Özden, Patrick Lebok, Guido Sauter, Uwe Heilenkötter, A von der Assen, Rainer Krech, M. Kluth, Volkmar Müller, Annette Lebeau, Khakan Hussein, Christian Wilke, Fritz Jänicke, A Hartmann, Ronald Simon, A. Mittenzwei, Linn Wölber, Peter Paluchowski, Luigi Terracciano, E Burandt, Billurvan Taskin, Isabell Witzel
Publikováno v:
Cancer Biology & Therapy. 16:1080-1087
Deletions of chromosome 8p occur frequently in breast cancers, but analyses of its clinical relevance have been limited to small patient cohorts and provided controversial results. A tissue microarray with 2,197 breast cancers was thus analyzed by fl
Autor:
Fritz Jänicke, Hans Kreipe, Walther Kuhn, Doris Augustin, Ronald E. Kates, Jens Huober, Arndt Hartmann, Volker Möbus, Nils Brünner, Annette Bartels, Ulrike Nitz, Svjetlana Mohrmann, Oleg Gluz, E Pelz, Nadia Harbeck, Christoph Thomssen, Ramona Erber, Zehra Moustafa, Marion Kiechle, Cornelia Liedtke
Publikováno v:
Breast Cancer Research and Treatment. 150:279-288
Taxane–anthracycline-based adjuvant chemotherapy is standard of care in patients with node-positive breast cancer (BC) but is also associated with severe side effects and significant costs. It is yet unclear, which biomarkers would predict benefit
Autor:
Cordula Petersen, Donata Grimm, Lisa Wagner, Sven Mahner, Fritz Jänicke, Fabian Trillsch, Linn Wölber
Publikováno v:
Frauenheilkunde up2date. 8:239-250