Metabolic support by macrophages sustains colonic epithelial homeostasis.

Autor: Fritsch SD; Center for Pathobiochemsitry & Genetics, Medical University of Vienna, Vienna, Austria., Sukhbaatar N; Center for Pathobiochemsitry & Genetics, Medical University of Vienna, Vienna, Austria., Gonzales K; Center for Pathobiochemsitry & Genetics, Medical University of Vienna, Vienna, Austria., Sahu A; Center for Pathobiochemsitry & Genetics, Medical University of Vienna, Vienna, Austria., Tran L; Department of Pathology, Medical University of Vienna, Vienna, Austria; Ludwig Boltzmann Institute Applied Diagnostics (LBI AD), Vienna, Austria., Vogel A; Institute for Vascular Biology, Center for Physiology and Pharmacology, Medical University Vienna, Vienna, Austria; Christian Doppler Laboratory Arginine Metabolism in Rheumatoid Arthritis and Multiple Sclerosis, Vienna, Austria., Mazic M; Center for Pathobiochemsitry & Genetics, Medical University of Vienna, Vienna, Austria., Wilson JL; Center for Pathobiochemsitry & Genetics, Medical University of Vienna, Vienna, Austria., Forisch S; Center for Pathobiochemsitry & Genetics, Medical University of Vienna, Vienna, Austria., Mayr H; Center for Pathobiochemsitry & Genetics, Medical University of Vienna, Vienna, Austria., Oberle R; Center for Pathobiochemsitry & Genetics, Medical University of Vienna, Vienna, Austria., Weiszmann J; Department of Ecogenomics and Systems Biology, University of Vienna, Vienna, Austria; Vienna Metabolomics Center (VIME), University of Vienna, Vienna, Austria., Brenner M; Department of Ecogenomics and Systems Biology, University of Vienna, Vienna, Austria; Department of Pharmaceutical Sciences/ Pharmacognosy, Faculty of Life Sciences, University of Vienna, Vienna, Austria; Vienna Metabolomics Center (VIME), University of Vienna, Vienna, Austria., Vanhoutte R; Laboratory of Chemical Biology, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium., Hofmann M; Institute for Vascular Biology, Center for Physiology and Pharmacology, Medical University Vienna, Vienna, Austria; Christian Doppler Laboratory Arginine Metabolism in Rheumatoid Arthritis and Multiple Sclerosis, Vienna, Austria., Pirnes-Karhu S; Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Magnes C; HEALTH-Institute for Biomedicine and Health Sciences, Joanneum Research Forschungsgesellschaft mbH, Graz, Austria., Kühnast T; Diagnostic and Research Department of Microbiology, Hygiene and Environmental Medicine, Medical University of Graz, Graz, Austria., Weckwerth W; Department of Ecogenomics and Systems Biology, University of Vienna, Vienna, Austria; Vienna Metabolomics Center (VIME), University of Vienna, Vienna, Austria., Bock C; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria; Institute of Artificial Intelligence, Center for Medical Statistics, Informatics, and Intelligent Systems, Medical University of Vienna, Vienna, Austria., Klavins K; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Hengstschläger M; Center for Pathobiochemsitry & Genetics, Medical University of Vienna, Vienna, Austria., Moissl-Eichinger C; Diagnostic and Research Department of Microbiology, Hygiene and Environmental Medicine, Medical University of Graz, Graz, Austria., Schabbauer G; Institute for Vascular Biology, Center for Physiology and Pharmacology, Medical University Vienna, Vienna, Austria; Christian Doppler Laboratory Arginine Metabolism in Rheumatoid Arthritis and Multiple Sclerosis, Vienna, Austria., Egger G; Department of Pathology, Medical University of Vienna, Vienna, Austria; Ludwig Boltzmann Institute Applied Diagnostics (LBI AD), Vienna, Austria., Pirinen E; Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Research Unit of Biomedicine and Internal Medicine, Faculty of Medicine, University of Oulu, Oulu, Finland; Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland., Verhelst SHL; Laboratory of Chemical Biology, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium., Weichhart T; Center for Pathobiochemsitry & Genetics, Medical University of Vienna, Vienna, Austria. Electronic address: thomas.weichhart@meduniwien.ac.at.

Publikováno v: Cell metabolism [Cell Metab] 2023 Nov 07; Vol. 35 (11), pp. 1931-1943.e8. Date of Electronic Publication: 2023 Oct 06.

Metabolic and immunologic control of intestinal cell function by mTOR.

Autor: Fritsch SD; Center of Pathobiochemistry and Genetics, Institute of Medical Genetics, Medical University of Vienna, Währinger Straße, Vienna, Austria., Weichhart T; Center of Pathobiochemistry and Genetics, Institute of Medical Genetics, Medical University of Vienna, Währinger Straße, Vienna, Austria.

Publikováno v: International immunology [Int Immunol] 2020 Jun 26; Vol. 32 (7), pp. 455-465.

Inactivation of mTORC2 in macrophages is a signature of colorectal cancer that promotes tumorigenesis.

Autor: Katholnig K; Center of Pathobiochemistry and Genetics, Institute of Medical Genetics., Schütz B; Center of Pathobiochemistry and Genetics, Institute of Medical Genetics., Fritsch SD; Center of Pathobiochemistry and Genetics, Institute of Medical Genetics., Schörghofer D; Center of Pathobiochemistry and Genetics, Institute of Medical Genetics., Linke M; Center of Pathobiochemistry and Genetics, Institute of Medical Genetics., Sukhbaatar N; Center of Pathobiochemistry and Genetics, Institute of Medical Genetics., Matschinger JM; Center of Pathobiochemistry and Genetics, Institute of Medical Genetics., Unterleuthner D; Center of Pathobiochemistry and Genetics, Institute of Medical Genetics., Hirtl M; Center of Pathobiochemistry and Genetics, Institute of Medical Genetics., Lang M; Department of Internal Medicine III, Division of Gastroenterology and Hepatology., Herac M; Clinical Institute of Pathology, and., Spittler A; Core Facility Flow Cytometry & Surgical Research Laboratories, Medical University of Vienna, Vienna, Austria., Bergthaler A; CeMM Research Center for Molecular Medicine, Austrian Academy of Sciences, Vienna, Austria., Schabbauer G; Institute for Physiology, Center for Physiology and Pharmacology, and., Bergmann M; Division of General Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria., Dolznig H; Center of Pathobiochemistry and Genetics, Institute of Medical Genetics., Hengstschläger M; Center of Pathobiochemistry and Genetics, Institute of Medical Genetics., Magnuson MA; Department of Molecular Physiology and Biophysics and Center for Stem Cell Biology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Mikula M; Center of Pathobiochemistry and Genetics, Institute of Medical Genetics., Weichhart T; Center of Pathobiochemistry and Genetics, Institute of Medical Genetics.

Publikováno v: JCI insight [JCI Insight] 2019 Oct 17; Vol. 4 (20). Date of Electronic Publication: 2019 Oct 17.

Effects of Interferons and Viruses on Metabolism.

Autor: Fritsch SD; Institute of Medical Genetics, Medical University of Vienna , Vienna , Austria., Weichhart T; Institute of Medical Genetics, Medical University of Vienna , Vienna , Austria.

Publikováno v: Frontiers in immunology [Front Immunol] 2016 Dec 21; Vol. 7, pp. 630. Date of Electronic Publication: 2016 Dec 21 (Print Publication: 2016).