Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Frits Meijlink"'
Autor:
Carolien Wansleeben, Léon van Gurp, Harma Feitsma, Carla Kroon, Ester Rieter, Marlies Verberne, Victor Guryev, Edwin Cuppen, Frits Meijlink
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19357 (2011)
BACKGROUND: Mutagenesis screens in the mouse have been proven useful for the identification of novel gene functions and generation of interesting mutant alleles. Here we describe a phenotype-based screen for recessive mutations affecting embryonic de
Externí odkaz:
https://doaj.org/article/5139dec19ac9416e8d5e82a3792a9c57
Autor:
Daisuke Matsumaru, Ryuma Haraguchi, Shinichi Miyagawa, Jun Motoyama, Naomi Nakagata, Frits Meijlink, Gen Yamada
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16260 (2011)
An omphalocele is one of the major ventral body wall malformations and is characterized by abnormally herniated viscera from the body trunk. It has been frequently found to be associated with other structural malformations, such as genitourinary malf
Externí odkaz:
https://doaj.org/article/ba1541f9af4542b29a51dbbcc0ce5aad
Autor:
Sophie I Candille, Catherine D Van Raamsdonk, Changyou Chen, Sanne Kuijper, Yanru Chen-Tsai, Andreas Russ, Frits Meijlink, Gregory S Barsh
Publikováno v:
PLoS Biology, Vol 2, Iss 1, p E3 (2004)
Many members of the animal kingdom display coat or skin color differences along their dorsoventral axis. To determine the mechanisms that control regional differences in pigmentation, we have studied how a classical mouse mutation, droopy ear (de(H))
Externí odkaz:
https://doaj.org/article/59e25caeb7fc4226814679ffee5cbd9e
Autor:
Mireille Montcouquiol, Frits Meijlink, Edwin Cuppen, Carla Kroon, Harma Feitsma, Carolien Wansleeben
Publikováno v:
Development, 137(7), 1067-1073. Company of Biologists Ltd
Among the cellular properties that are essential for the organization of tissues during animal development, the importance of cell polarity in the plane of epithelial sheets has become increasingly clear in the past decades. Planar cell polarity (PCP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ead677a54a20175de6f8b102fc7419f8
https://hdl.handle.net/20.500.11755/b44c5799-3550-46ec-ac13-c6e9563dbb4f
https://hdl.handle.net/20.500.11755/b44c5799-3550-46ec-ac13-c6e9563dbb4f
Autor:
Rüdiger J. Blaschke, Lambertus J. Wisse, Wolfgang Rottbauer, Stefan E. Hardt, Sanne Kuijper, Frits Meijlink, Hans R. Schöler, Adriana C. Gittenberger-de Groot, Kirsten Deissler, Martin Blum, Gudrun A. Rappold, Steffen Just, Jessica Spitzer, Nathan D. Hahurij, Tina Maxelon, Konstantinos Anastassiadis, Harma Feitsma
Publikováno v:
Circulation. 115:1830-1838
Background— Identifying molecular pathways regulating the development of pacemaking and coordinated heartbeat is crucial for a comprehensive mechanistic understanding of arrhythmia-related diseases. Elucidation of these pathways has been complicate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e26fc877179b5f385f3f3b4c3a6a9f7a
https://doi.org/10.1161/circulationaha.106.637819
https://doi.org/10.1161/circulationaha.106.637819
Publikováno v:
Developmental Biology. 285:533-544
The role of the aristaless-related homeobox gene Alx4 in antero-posterior (AP-) patterning of the developing vertebrate limb has remained somewhat elusive. Polydactyly of Alx4 mutant mice is known to be accompanied by ectopic anterior expression of g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ad08c486b9f002255be70f52683388
https://doi.org/10.1016/j.ydbio.2005.06.017
https://doi.org/10.1016/j.ydbio.2005.06.017
Publikováno v:
Gene Expression Patterns. 4:243-247
The precise anterior boundaries of Hox expression domains are critical for correct antero-posterior (A-P) patterning of the vertebrate longitudinal axis. Retinoic acid (RA) signalling has been shown to play an important role in the specification of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc4bc81cdee6865c2243df2ad857c386
https://doi.org/10.1016/j.modgep.2003.11.007
https://doi.org/10.1016/j.modgep.2003.11.007
Publikováno v:
Journal of Biological Chemistry. 278:24103-24107
During embryogenesis, target genes of retinoid signaling are able to respond differently to identical concentrations of retinoids. Small differences in the retinoic acid response elements (RARE) may be essential for these distinct responses. Recently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fd007be8f5d922a6dfd6e7b0f02b818
https://doi.org/10.1074/jbc.m300774200
https://doi.org/10.1074/jbc.m300774200
Publikováno v:
Mechanisms of Development. 120(2):241-252
Aristaless-related genes encode a structurally defined group of homeoproteins that share a C-terminal stretch of amino acids known as the OAR- or aristaless domain. Many aristaless-related genes have been linked to major developmental functions, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18440a514342b8e3ec7686b2ab8e1ed8
Autor:
Frits Meijlink, Jacqueline Deschamps, Pierre Chambon, Karen Niederreither, Tony Oosterveen, Pascal Dollé
Publikováno v:
The EMBO Journal. 22:262-269
We describe the regulatory interactions that cause anterior extension of the mouse 5′ Hoxb expression domains from spinal cord levels to their definitive boundaries in the posterior hindbrain between embryonic day E10 and E11.5. This anterior expan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72bf4c916329216e1c196a8d6248fc04
https://doi.org/10.1093/emboj/cdg029
https://doi.org/10.1093/emboj/cdg029