Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Frithjof Wickrath"'
Autor:
Hans-Wilhelm Müller, Joseph P. Huston, Susanne Nikolaus, Hans-Jörg Wittsack, Frithjof Wickrath, Markus Beu, Eduards Mamlins, Maria A. de Souza Silva, Christina Antke, Anja Müller-Lutz, Hubertus Hautzel, Gerald Antoch
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
D-cycloserine (DCS) and amantadine (AMA) act as partial NMDA receptor (R) agonist and antagonist, respectively. In the present study, we compared the effects of DCS and AMA on dopamine D2/3R binding in the brain of adult rats in relation to motor beh
Autor:
Joseph P. Huston, Maria A. de Souza Silva, Christina Antke, Anja Müller-Lutz, Markus Beu, Hans-Jörg Wittsack, Hans-Wilhelm Müller, Hubertus Hautzel, Susanne Nikolaus, Frithjof Wickrath, Gerald Antoch
Publikováno v:
Pharmacology Biochemistry and Behavior. 179:156-170
Purpose The present study assessed the influence of the NMDA receptor (R) antagonist amantadine (AMA) on cerebral dopamine D2/3R binding in relation to motor and exploratory activity in the rat. Methods D2/3R binding was determined in anaesthetized a
Autor:
Christian Herder, Frithjof Wickrath, Michael Roden, Jong-Hee Hwang, John G. Jones, Pavel Bobrov, Daniel F. Markgraf, Sabine Kahl, Cristina Barosa, Oana-Patricia Zaharia, Julia Szendroedi, Theresia Sarabhai
Publikováno v:
JCI Insight
BACKGROUND: While saturated fat intake leads to insulin resistance and nonalcoholic fatty liver, Mediterranean-like diets enriched in monounsaturated fatty acids (MUFA) may have beneficial effects. This study examined effects of MUFA on tissue-specif
Autor:
Susanne, Nikolaus, Hans-Jörg, Wittsack, Frithjof, Wickrath, Anja, Müller-Lutz, Hubertus, Hautzel, Markus, Beu, Christina, Antke, Eduards, Mamlins, Maria Angelica, De Souza Silva, Joseph P, Huston, Gerald, Antoch, Hans-Wilhelm, Müller
Publikováno v:
Scientific Reports
D-cycloserine (DCS) and amantadine (AMA) act as partial NMDA receptor (R) agonist and antagonist, respectively. In the present study, we compared the effects of DCS and AMA on dopamine D2/3R binding in the brain of adult rats in relation to motor beh
Autor:
Alfons Schnitzler, Georg Oeltzschner, Helge J. Zöllner, Hans Jörg Wittsack, Frithjof Wickrath
Publikováno v:
Magnetic Resonance Imaging. 34:1057-1063
To compare two different methods of obtaining the water reference for determination of quantitative water-scaled in vivo concentration estimates of γ-aminobutyric acid (GABA).Water-scaled GABA estimates from localized J-difference edited MR spectros
Autor:
Hans-Jörg Wittsack, Johannes Boos, Tom Cronenberg, Anja Müller-Lutz, Frithjof Wickrath, Christoph Schleich, Moritz Zaiss
Publikováno v:
Magnetic Resonance in Medicine. 78:280-284
Purpose To investigate, if a train of spin-lock pulses (chemical exchange saturation transfer with spin-lock pulses = CESL) improves biochemical glycosaminoglycan imaging compared with conventional chemical exchange saturation transfer with Gaussian-
Autor:
Benjamin Schmitt, Hans-Jörg Wittsack, Johannes Boos, Anja Müller-Lutz, Felix Matuschke, Christoph Schleich, Frithjof Wickrath
Publikováno v:
Magnetic Resonance Imaging. 34:771-778
Purpose To optimize B 0 -field inhomogeneity correction for chemical exchange saturation transfer (CEST) imaging by investigating different water saturation shift referencing (WASSR) Z-spectrum shapes and different frequency correction techniques. Me
Autor:
Jürgen Bunke, Jong-Hee Hwang, Guido Giani, Frithjof Wickrath, Alessandra Laufs, Roshan S Livingstone, Bettina Nowotny, Michael Roden, Peter Nowotny
Publikováno v:
Magnetic Resonance in Medicine. 71:1670-1675
Purpose The aims of this study were (i) to establish a robust and fast method to quantify hepatocellular phosphorus compounds in molar concentration on a 3T clinical scanner, (ii) to evaluate its reproducibility, and (iii) to test its feasibility for
Autor:
Anja, Müller-Lutz, Tom, Cronenberg, Christoph, Schleich, Frithjof, Wickrath, Moritz, Zaiss, Johannes, Boos, Hans-Jörg, Wittsack
Publikováno v:
Magnetic resonance in medicine. 78(1)
To investigate, if a train of spin-lock pulses (chemical exchange saturation transfer with spin-lock pulses = CESL) improves biochemical glycosaminoglycan imaging compared with conventional chemical exchange saturation transfer with Gaussian-shaped p
Covert hepatic encephalopathy: elevated total glutathione and absence of brain water content changes
Publikováno v:
Metabolic brain disease. 31(3)
Recent pathophysiological models suggest that oxidative stress and hyperammonemia lead to a mild brain oedema in hepatic encephalopathy (HE). Glutathione (GSx) is a major cellular antioxidant and known to be involved in the interception of both. The