A characterization of cis- and trans-heritability of RNA-Seq-based gene expression

Autor: Ouwens, K.G., Jansen, R., Nivard, M.G., Dongen, J. van, Frieser, M.J., Hottenga, J.J., Arindrarto, W., Claringbould, A., Iterson, M. van, Mei, H.L., Franke, L., Heijmans, B.T., Hoen, P.A.C. 't, Meurs, J. van, Brooks, A.I., Penninx, B.W.J.H., Boomsma, D.I., Isaacs, A., Pool, R., Greevenbroek, M.M.J. van, Stehouwer, C.D.A., Kallen, C.J.H. van der, Schalkwijk, C.G., Wijmenga, C., Zhernakova, S., Tigchelaar, E.F., Slagboom, P.E., Beekman, M., Deelen, J., Heemst, D. van, Veldink, J.H., Berg, L.H. van den, Duijn, C.M. van, Hofman, B.A., Uitterlinden, A.G., Jhamai, P.M., Verbiest, M., Suchiman, H.E.D., Verkerk, M., Breggen, R. van der, Rooij, J. van, Lakenberg, N., Galen, M. van, Bot, J., Zhernakova, D.V., van't Hof, P., Deelen, P., Nooren, I., Moed, M., Vermaat, M., Luijk, R., Bonder, M.J., Dijk, F. van, Kielbasa, S.M., Swertz, M.A., Zwet, E.W. van, Hoen, P.B. 't, BIOS Consortium

Publikováno v: Ouwens, K G, Jansen, R, Nivard, M G, van Dongen, J, Frieser, M J, Hottenga, J-J, Arindrarto, W, Claringbould, A, van Iterson, M, Mei, H, Franke, L, Heijmans, B T, A. C. ’t Hoen, P, van Meurs, J, Brooks, A I, Boomsma, D I, Penninx, B W J H & BIOS Consortium 2020, ' A characterization of cis-and trans-heritability of RNA-Seq-based gene expression ', European Journal of Human Genetics, vol. 28, no. 2, pp. 253-263 . https://doi.org/10.1038/s41431-019-0511-5
European Journal of Human Genetics, 28(2), 253-263. Nature Publishing Group
Ouwens, K G, Jansen, R, Nivard, M G, van Dongen, J, Hottenga, J-J, Penninx, B W J H, Boomsma, D I & BIOS Consortium 2020, ' A characterization of cis-and trans-heritability of RNA-Seq-based gene expression ', European Journal of Human Genetics, vol. 28, no. 2, pp. 253-263 . https://doi.org/10.1038/s41431-019-0511-5
European Journal of Human Genetics, 28, 253-263
Eur J Hum Genet
European Journal of Human Genetics, 28, 2, pp. 253-263
European Journal of Human Genetics, 28(2), 253-263. NATURE PUBLISHING GROUP

Insights into individual differences in gene expression and its heritability (h2) can help in understanding pathways from DNA to phenotype. We estimated the heritability of gene expression of 52,844 genes measured in whole blood in the largest twin R

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https://research.vumc.nl/en/publications/029df33c-d648-47cb-b258-60c60eed93d1

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