Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Friedrich von der Haar"'
Autor:
Jean Gangloff, Friedrich von der Haar, Ricardo Ehrlich, Pierre Remy, Hassen Bacha, Jean-François Lefèvre, Michel Renaud
Publikováno v:
European Journal of Biochemistry. 117:439-447
The fluorescence properties of yeast tRNAPheCCF (tRNAPhe in which the 3′-terminal adenosine has been replaced by formycin) and tRNAPheCCFoxi-redafter periodate oxidation followed by borohydride reduction) were studied in the complex with the cognat
Autor:
Friedrich von der Haar
Publikováno v:
Biomedizinische Technik/Biomedical Engineering. 36:11-14
Publikováno v:
European Journal of Biochemistry. 64:389-393
Eighteen analogs of ATP have been tested in the aminoacylation reaction of phenylalanyl-tRNA and seryl-tRNA synthetases from baker's yeast. Four compounds. are substrates for phenylalanylLRNA syntiteiase, live for seryl-tRNA synthetase, one compound
Publikováno v:
Nucleic Acids Research. 14:7529-7538
Three analogues each of leucine and isoleucine carrying hydroxy groups in gamma- or delta- or gamma- and delta-position have been synthesized, and tested in the aminoacylation by leucyl-tRNA synthetases from E. coli and yeast. Hydrolytic proofreading
Publikováno v:
Nucleic Acids Research. 3:2233-2242
The kinetics of U-U-C-A binding to the dodecanucleotide (A-Cm-U-Gm-A-A-Y-A-psi-m5C-U-Gp) isolated from the anticodon region of yeast tRNA-Phe are similar to the kinetics of binding of U-U-C-A to intact tRNA-Phe. A large enhancement in binding constan
Publikováno v:
Angewandte Chemie. 93:250-256
Das „masgeschneiderte” Arzneimittel ist ein alter Traum seit Paracelsus′: „Dosis sola facit venenum”. Ein ideales Pharmakon sollte den pathologischen Vorgang oder den parasitaren Organismus maximal inhibieren und dabei den menschlichen Korp
Publikováno v:
European Journal of Biochemistry. 76:263-267
Because of its chiralic alpha-phosphorus atom adenosine 5'-O-(1-thiotriphosphate) (ATPalphaS) exists in two diastereomeric forms, arbitrarily named (A) and (B). For phenylalanyl-tRNA synthetase ATPalphaS (A) is a substrate whereas ATPalphaS (B) is ne
Publikováno v:
Angewandte Chemie International Edition in English. 20:217-223
The “tailor-made” pharmaceutical has been an old dream ever since Paracelsus' days. His saying “Dosis sola facit venenum” is still valid. The ideal pharmacon should inhibit the pathological process or the parasitical organism to a maximum whi
Publikováno v:
Biochemical and Biophysical Research Communications. 59:22-29
Summary The proton resonances of 13 methyl groups and 4 methylene groups belonging to 12 modified bases in tRNAyeastPhe were investigated by 220 MHz NMR spectrometry. The chemical shifts and the linewidths at half height of these assigned resonances
Autor:
Friedrich von der Haar
Publikováno v:
Biochemical and Biophysical Research Communications. 70:1009-1013
Proteins can be precipitated onto the surface of unsubstituted agarose at an ammonium sulfate concentration about 10% lower than needed for precipitation out of solution. The protein is fractionally redissolved by developing agarose columns with a li