Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Friedrich Wartlick"'
Autor:
Friedrich Wartlick, Christian Henninger, Bernd Kaina, C. Hinterleitner, Johannes Huelsenbeck, Anne Schorr, Gerhard Fritz
Publikováno v:
Apoptosis. 18:963-979
We investigated the relevance of signaling mechanisms regulated by the Ras-homologous GTPase Rac1 for survival of acute myeloid leukemia (AML) cells harbouring the MLL-AF9 oncogene due to t(9;11)(p21;q23) translocation. Monocytic MLL-AF9 expressing c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d802719205645a3c1f75d99c7fc9bb6c
https://doi.org/10.1007/s10495-013-0842-6
https://doi.org/10.1007/s10495-013-0842-6
Autor:
Bernd Kaina, Michael Schwarz, Gerhard Fritz, Friedrich Wartlick, Christian Henninger, Anita Bopp
Publikováno v:
Carcinogenesis. 36(3)
To elucidate the function of the Ras-homologous GTPase Rac1 in hepatocarcinogenesis induced by diethylnitrosamine (DEN), mice lacking hepatic Rac1 expression were treated with DEN and compared to the wild-type (WT). Rac1 knock-out (KO) mice were foun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63e7f0d7a3a3909a97929fb143960f0c
https://pubmed.ncbi.nlm.nih.gov/25556150
https://pubmed.ncbi.nlm.nih.gov/25556150
Publikováno v:
Cell Death & Disease
To investigate the importance of the Ras-homologous GTPase Rac1 for the hepatic response to genotoxic insults and liver aging, rac1 was deleted in liver of mice by Mx1-Cre-based recombination. Knockout of rac1 caused complex changes in basal as well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::880bd0b162e2aa7b7d5169aea37e629f
http://europepmc.org/articles/PMC3613835
http://europepmc.org/articles/PMC3613835
Publikováno v:
European Journal of Cancer. 48:S165
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91e416195603892a20b24445e51f1aa8
https://doi.org/10.1016/s0959-8049(12)71340-0
https://doi.org/10.1016/s0959-8049(12)71340-0
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. (12):3093-3103
Here, we investigated the influence of Rac family small GTPases on mechanisms of the DNA damage response (DDR) stimulated by topoisomerase II poisons. To this end, we examined the influence of the Rac-specific small molecule inhibitor EHT1864 on Ser1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f352af35e3fd6359a1a3ab8a032ca40c