Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Friedrich Kopp"'
Autor:
Jacob Schmidt, Abdulbaki Yakac, Robert Peters, Frank Friedersdorff, Karoline Kernig, Anna Kienel, Franziska I. Winterhagen, Friedrich Köpp, Susan Foller, Francesca DiQuilio, Karl Weigand, Luka Flegar, Philipp Reimold, Michael Stöckle, Juliane Putz, Philip Zeuschner
Publikováno v:
European Urology Open Science, Vol 67, Iss , Pp 45-53 (2024)
Background and objective: Kidney transplant recipients (KTRs) have an increased risk of developing genitourinary cancers, including prostate cancer (PCa), which is expected to become more prevalent due to an aging KTR population. Thus, knowledge of s
Externí odkaz:
https://doaj.org/article/fcf52f44162f41f6a212a845b0bdb811
Publikováno v:
Journal of Molecular Biology. 313:465-471
The activity of the proteasome, the major non-lysosomal proteinase in eukaryotes, is stimulated by two activator complexes, PA700 and PA28. PA700–20 S-PA700 proteasome complexes, generally designated as 26 S proteasomes, degrade proteins, whereas c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d66a34c6b184d4da381a47a2609f5a06
https://doi.org/10.1006/jmbi.2001.5063
https://doi.org/10.1006/jmbi.2001.5063
Autor:
Wolfgang Uerkvitz, Klavs B. Hendil, Axel Sobek, Burkhardt Dahlmann, Friedrich Kopp, Poul Kristensen
Publikováno v:
Proceedings of the National Academy of Sciences. 94:2939-2944
In human 20S proteasomes two copies of each of seven different α-type and seven different β-type subunits are assembled to form a stack of four seven-membered rings, giving the general structure α1–7, β1–7, β1–7, α1–7. By means of immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d9930714dae9bc198ae69fd143ef3b5
https://doi.org/10.1073/pnas.94.7.2939
https://doi.org/10.1073/pnas.94.7.2939
Autor:
Burkhardt Dahlmann, Klavs B. Hendil, Friedrich Kopp, Axel Sobek, Anders H. Johnsen, Poul Kristensen
Publikováno v:
Journal of Molecular Biology. 248:264-272
Subunit HsN3 of the human proteasome is a β-type subunit homologous toPRE4 from yeast, X1β from Xenopus and RN3 from the rat. Using electron microscopy, the binding sites of a monoclonal antibody with specificity for subunit HsN3 have been located
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d149cb5e764da0460890089911e72d2
https://doi.org/10.1016/s0022-2836(95)80049-2
https://doi.org/10.1016/s0022-2836(95)80049-2
Autor:
Burkhardt Dahlmann, Axel Sobek, Barbara Becher, Friedrich Kopp, Lothar Kuehn, Christian Ehlers
Publikováno v:
Enzyme and Protein. 47:274-284
The effect of chemical compounds like sodium dodecyl sulfate (SDS), fatty acid esters of glycerol, carnitine and coenzyme A, phospholipids, histones, polylysines as well as homobifunctional chemical cross-linkers on the various proteolytic activities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3247745cc4db3dfbd9b69bb4811bf166
https://doi.org/10.1159/000468685
https://doi.org/10.1159/000468685
Publikováno v:
FEBS Letters. 290:186-190
The subunit topography of the Thermoplasma acidophilum proteasome was determined by immunoelectron microscopy using monospecific antibodies directed against the two constituent subunits (alpha,beta). Anti-alpha-subunit IgG was found to bind to the ou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::445b350b469fc2aeb756c1bb69b7d33b
https://doi.org/10.1016/0014-5793(91)81256-8
https://doi.org/10.1016/0014-5793(91)81256-8
Autor:
Wolfgang Baumeister, Günter Pfeifer, Friedrich Kopp, Friedrich Lottspeich, Peter Zwickl, Burkhardt Dahlmann
Publikováno v:
Journal of Structural Biology. 103:197-203
In an attempt to settle the question of whether the multicatalytic proteinase or proteasome exist in all three kingdoms of life—eukaryotes, archaebacteria, and eubacteria—we have undertaken a search for them in the eubacterium Comamonas acidovora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80c67210e17f6fd83c8ea39f5e8e41fe
https://doi.org/10.1016/1047-8477(90)90037-d
https://doi.org/10.1016/1047-8477(90)90037-d
Autor:
Friedrich Kopp, Lothar Kuehn
Publikováno v:
Journal of molecular biology. 329(1)
Specific labelling with monoclonal antibodies reveals that in regulator-proteasome complexes the asymmetric 19S regulator (PA700) binds to one or both terminal alpha-disks of the cylinder-shaped 20S core proteasome in such a way that its reclining fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83745fce861dcad132da722272015ded
https://pubmed.ncbi.nlm.nih.gov/12742014
https://pubmed.ncbi.nlm.nih.gov/12742014
Publikováno v:
Journal of hepatology. 31(6)
Background: Acute liver failure may be the first manifestation of Wilson disease. If copper elimination fails, liver transplantation is the only remaining therapeutic option. Albumin dialysis, a new method for the removal of protein-bound toxins, was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13650d47a6e30a27d8759ea46ac5e14d
https://pubmed.ncbi.nlm.nih.gov/10604583
https://pubmed.ncbi.nlm.nih.gov/10604583
Publikováno v:
Archives of biochemistry and biophysics. 363(2)
The arrangement of subunits in human 20S proteasomes was recently determined by us by immunoelectron microscopy and chemical cross-linking. The positions of 4 of the 14 subunits differed from those found in the yeast proteasome by X-ray crystallograp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::898a1e74965b9c510314af951f801144
https://pubmed.ncbi.nlm.nih.gov/10068451
https://pubmed.ncbi.nlm.nih.gov/10068451