Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Friedrich Grummt"'
Autor:
Ivaylo Gentschev, Meike Müller, Marion Adelfinger, Stephanie Weibel, Friedrich Grummt, Martina Zimmermann, Michael Bitzer, Martin Heisig, Qian Zhang, Yong A Yu, Nanhai G Chen, Jochen Stritzker, Ulrich M Lauer, Aladar A Szalay
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22069 (2011)
Virotherapy using oncolytic vaccinia virus strains is one of the most promising new strategies for cancer therapy. In this study, we analyzed for the first time the therapeutic efficacy of the oncolytic vaccinia virus GLV-1h68 in two human hepatocell
Externí odkaz:
https://doaj.org/article/bbf34c15ed384023ab8a0fd2bc86e33e
Interactions and subcellular distribution of DNA replication initiation proteins in eukaryotic cells
Publikováno v:
Molecular Genetics and Genomics. 278:623-632
For initiation of eukaryotic DNA replication the origin recognition complex (ORC) associates with chromatin sites and constitutes a landing pad allowing Cdc6, Cdt1 and MCM proteins to accomplish the pre-replication complex (pre-RC). In S phase, the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd81229bc0ee921dd3a7cec2ac4b5d4a
https://doi.org/10.1007/s00438-007-0278-1
https://doi.org/10.1007/s00438-007-0278-1
Autor:
Friedrich Grummt, Vera Pütter
Publikováno v:
EMBO reports. 3:147-152
In mammals, sequence-specific termination of DNA replication within the ribosomal RNA genes is catalyzed by a defined DNA-protein complex that includes transcription termination factor I (TTF-I). Here we show that TTF-I acts as a polar contrahelicase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d18dd3119f16561ed445fcb2bef8c929
https://doi.org/10.1093/embo-reports/kvf027
https://doi.org/10.1093/embo-reports/kvf027
Publikováno v:
Chromosoma. 108:243-249
Two new members of the mouse origin recognition complex (ORC) have been cloned that are closely related to Saccharomyces cerevisiae ORC4 and ORC5 as well as to their human homolog. Both MmORC4p and MmORC5p have a putative nucleotide triphosphate bind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e71b056c5818cea3bc740e732f55eaed
https://doi.org/10.1007/s004120050374
https://doi.org/10.1007/s004120050374
Publikováno v:
Cytogenetic and Genome Research. 87:245-251
A new member of the murine origin recognition complex (ORC) related to Saccharomyces cerevisiae ORC3 has been cloned. Transcription of ORC3 is not suppressed in mouse NIH3T3 fibroblasts made quiescent by serum starvation. The transcription level of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9248931c286a07b6d96ca0f39ea6bb42
https://doi.org/10.1159/000015435
https://doi.org/10.1159/000015435
Publikováno v:
Molecular and General Genetics MGG. 260:295-299
ORC1 encodes a subunit of the eukaryotic origin recognition complex in yeast, which has been shown to play a crucial role in chromosomal DNA replication and transcriptional silencing. We have identified a mouse protein closely related to Saccharomyce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0384ecc9193a79dcccf69b3c066e97f2
https://doi.org/10.1007/s004380050898
https://doi.org/10.1007/s004380050898
Autor:
Friedrich Grummt, Caroline Staib
Publikováno v:
Methods. 13:293-300
The mapping of replication origins by nascent DNA strand length determination is a very sensitive generally applicable method that identifies even single-copy origins in mammalian chromosomes. A major advantage of this procedure is that there is no n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c543b01bcfb53af711ab7bfa5e84cb97
https://doi.org/10.1006/meth.1997.0528
https://doi.org/10.1006/meth.1997.0528
Publikováno v:
Journal of Interferon & Cytokine Research. 16:595-600
Interleukin 2 (IL-2) and interleukin 4 (IL-4) secreted by activated but not by resting mature T cells are pleiotropic cytokines affecting growth and differentiation of diverse cell types, such as T cells, B cells, and mast cells. There is little info
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a61ca1391a4a5ac0d88090e9718c9f9
https://doi.org/10.1089/jir.1996.16.595
https://doi.org/10.1089/jir.1996.16.595
Publikováno v:
Chromosoma. 103:209-214
MuNTS2, a 423 bp sequence isolated from the non-transcribed spacer of murine rDNA stimulates the amplification of cis-linked plasmid DNA in mouse cells under selective conditions. Here we demonstrate that a 180 bp subdomain of muNTS2 is highly homolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1a40f7d3a406939ce8ef63a88817641
https://doi.org/10.1007/bf00368014
https://doi.org/10.1007/bf00368014
Publikováno v:
Virology. 197:537-548
The requirements for the DNA replication of the human papovavirus JC were analyzed using JC T-antigen as well as the T-antigens of the related viruses SV40 and BK. With all three T-antigens, the boundary of the core origin mapped on the early side to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a776d8784c3bc9858ed98651b8c38dc0
https://doi.org/10.1006/viro.1993.1627
https://doi.org/10.1006/viro.1993.1627