Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Friedrich Grässer"'
Autor:
Adam W. Whisnant, Christopher S. Jürges, Thomas Hennig, Emanuel Wyler, Bhupesh Prusty, Andrzej J. Rutkowski, Anne L’hernault, Lara Djakovic, Margarete Göbel, Kristina Döring, Jennifer Menegatti, Robin Antrobus, Nicholas J. Matheson, Florian W. H. Künzig, Guido Mastrobuoni, Chris Bielow, Stefan Kempa, Chunguang Liang, Thomas Dandekar, Ralf Zimmer, Markus Landthaler, Friedrich Grässer, Paul J. Lehner, Caroline C. Friedel, Florian Erhard, Lars Dölken
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Here, using computational integration of multi-omics data, the authors provide a detailed transcriptome and translatome of herpes simplex virus 1 (HSV-1), including previously unidentified ORFs and N-terminal extensions. The study also provides a HSV
Externí odkaz:
https://doaj.org/article/2bc69e036d254f1f89647997e0dbd0b2
Autor:
Emanuel Wyler, Vedran Franke, Jennifer Menegatti, Christine Kocks, Anastasiya Boltengagen, Samantha Praktiknjo, Barbara Walch-Rückheim, Jens Bosse, Nikolaus Rajewsky, Friedrich Grässer, Altuna Akalin, Markus Landthaler
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Herpes simplex virus 1 (HSV-1) induces major reprogramming of the host cell environment. Here, the authors profile the transcriptomes of individual HSV-1-infected human fibroblasts and provide evidence of an antiviral program mediated by the activati
Externí odkaz:
https://doaj.org/article/9b9106fe09bb41628a077aaba85373ab
Autor:
Sven Wach, Madeleine Brandl, Hannes Borchardt, Katrin Weigelt, Sabine Lukat, Elke Nolte, Omar Al-Janabi, Martin Hart, Friedrich Grässer, Johannes Giedl, Rudolf Jung, Robert Stöhr, Arndt Hartmann, Verena Lieb, Sabrina Höbel, Anna Peters, Claudia Stäubert, Bernd Wullich, Helge Taubert, Achim Aigner
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 16, Iss , Pp 272-283 (2019)
MIR143 is pathologically downregulated and may function as a tumor suppressor in prostate cancer. Likewise, the urokinase plasminogen activator receptor (UPAR) is overexpressed in prostate carcinoma, representing a negative prognostic marker and puta
Externí odkaz:
https://doaj.org/article/d8d765c582e04b049197e5a16a0b421e
Autor:
Emanuel Wyler, Jennifer Menegatti, Vedran Franke, Christine Kocks, Anastasiya Boltengagen, Thomas Hennig, Kathrin Theil, Andrzej Rutkowski, Carmelo Ferrai, Laura Baer, Lisa Kermas, Caroline Friedel, Nikolaus Rajewsky, Altuna Akalin, Lars Dölken, Friedrich Grässer, Markus Landthaler
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-19 (2017)
Abstract Background Herpesviruses can infect a wide range of animal species. Herpes simplex virus 1 (HSV-1) is one of the eight herpesviruses that can infect humans and is prevalent worldwide. Herpesviruses have evolved multiple ways to adapt the inf
Externí odkaz:
https://doaj.org/article/24f82393e5a34eb78b2da72c1ef5b9d1
Autor:
Jessica Hoppstädter, Britta Diesel, Rebecca Linnenberger, Nina Hachenthal, Sara Flamini, Marie Minet, Petra Leidinger, Christina Backes, Friedrich Grässer, Eckart Meese, Stefano Bruscoli, Carlo Riccardi, Hanno Huwer, Alexandra K. Kiemer
Publikováno v:
Frontiers in Immunology, Vol 9 (2019)
Activation of toll-like receptors (TLRs) plays a pivotal role in the host defense against bacteria and results in the activation of NF-κB-mediated transcription of proinflammatory mediators. Glucocorticoid-induced leucine zipper (GILZ) is an anti-in
Externí odkaz:
https://doaj.org/article/bbcc7e762c4148f0883a19e1d67903c3
Autor:
Lena Krammes, Martin Hart, Stefanie Rheinheimer, Caroline Diener, Jennifer Menegatti, Friedrich Grässer, Andreas Keller, Eckart Meese
Publikováno v:
Cells, Vol 9, Iss 6, p 1442 (2020)
Neurodegenerative disorders such as Alzheimer’s disease (AD) and Parkinson’s disease (PD) are characterized by the accumulation of misfolded proteins in the endoplasmic reticulum (ER) and the unfolded protein response (UPR). Modulating the UPR is
Externí odkaz:
https://doaj.org/article/04dd30ac92614560959c06b54d8d20bd
Autor:
Anna M Marthaler, Marta Podgorska, Pascal Feld, Alina Fingerle, Katrin Knerr-Rupp, Friedrich Grässer, Hans Smola, Klaus Roemer, Elke Ebert, Yoo-Jin Kim, Rainer M Bohle, Cornelia S L Müller, Jörg Reichrath, Thomas Vogt, Magdalena Malejczyk, Sławomir Majewski, Sigrun Smola
Publikováno v:
PLoS Pathogens, Vol 13, Iss 6, p e1006406 (2017)
Patients suffering from Epidermodysplasia verruciformis (EV), a rare inherited skin disease, display a particular susceptibility to persistent infection with cutaneous genus beta-human papillomavirus (beta-HPV), such as HPV type 8. They have a high r
Externí odkaz:
https://doaj.org/article/3f8f4aae35a8424c91ee2b36e349ab53
Autor:
Friedrich Grässer, Bernd Wullich, Arndt Hartmann, Robert Stöhr, Wolf Wieland, Rainer Grobholz, Stephanie Barth, Gerhard Unteregger, Volker Jung, Sven Wach, Elke Löprich, Jaroslaw Szczyrba
Supplementary Data from The MicroRNA Profile of Prostate Carcinoma Obtained by Deep Sequencing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3fcefa1bbdd8c6c2b8376efa382f673
https://doi.org/10.1158/1541-7786.22519029
https://doi.org/10.1158/1541-7786.22519029
Autor:
Friedrich Grässer, Bernd Wullich, Arndt Hartmann, Robert Stöhr, Wolf Wieland, Rainer Grobholz, Stephanie Barth, Gerhard Unteregger, Volker Jung, Sven Wach, Elke Löprich, Jaroslaw Szczyrba
Prostate cancer is a leading cause of tumor mortality. To characterize the underlying molecular mechanisms, we have compared the microRNA (miRNA) profile of primary prostate cancers and noncancer prostate tissues using deep sequencing. MiRNAs are sma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f97d62ffd56197852f0bdaeeb3f56ba
https://doi.org/10.1158/1541-7786.c.6542247
https://doi.org/10.1158/1541-7786.c.6542247
Autor:
Adam W. Whisnant, Christopher S. Jürges, Thomas Hennig, Emanuel Wyler, Bhupesh Prusty, Andrzej J. Rutkowski, Anne L’hernault, Lara Djakovic, Margarete Göbel, Kristina Döring, Jennifer Menegatti, Robin Antrobus, Nicholas J. Matheson, Florian W. H. Künzig, Guido Mastrobuoni, Chris Bielow, Stefan Kempa, Chunguang Liang, Thomas Dandekar, Ralf Zimmer, Markus Landthaler, Friedrich Grässer, Paul J. Lehner, Caroline C. Friedel, Florian Erhard, Lars Dölken
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The predicted 80 open reading frames (ORFs) of herpes simplex virus 1 (HSV-1) have been intensively studied for decades. Here, we unravel the complete viral transcriptome and translatome during lytic infection with base-pair resolution by computation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::85d64d82cd9ae22c2d804e9169868e9f